XBIvsETF 2ETF Comparison
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Choose a second ETF to run a side-by-side ETF comparison with XBI, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XBI performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XBI ETF 2 | +11.52%– | +4.22%– | +9.28%– | +65.29%– | +64.93%– | -3.74%– |
| Flows | XBI ETF 2 | +$314M– | -$560M– | -$19M– | +$404M– | -$1.15B– | +$839M– |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XBI ETF 2 | +30.22%– | +25.87%– | +27.40%– | +32.69%– |
| Max drawdown | XBI ETF 2 | -7.98%– | -9.66%– | -32.94%– | -55.10%– |
| Max drawdown duration | XBI ETF 2 | 42d– | 76d– | 331d– | 1822d– |
Trading data
XBI | ETF 2 | |
Last sale 4/24/2026 at 1:30 PM | $133.28 | – |
| Previous close 04/23/2026 | $134.49 | – |
| Consolidated volume 04/23/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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XBI | ETF 2 | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
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| Average | ||
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Main metrics
Last update 4/24/2026 at 1:30 PM
Live
Closed
XBI | ETF 2 | |
|---|---|---|
| Last price | $133.28 | – |
| 1D performance | -0.90% | – |
| AuM | $8.52 B | – |
| E/R | 0.35% | – |
Characteristics
XBI | ETF 2 | |
|---|---|---|
| Management strategy | Passive | – |
| Provider | State Street Investment Management | – |
| Benchmark | S&P Biotechnology Select Industry Index | – |
| N° of holdings | 122 | – |
| Asset class | Equities | – |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 31, 2006 | – |
| ESG | No | – |
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Exposure
Countries
XBI
USA
95.16%
Other
4.84%
ETF 2
Sectors
XBI
Health Care
86.79%
Other
13.21%
ETF 2
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Diversification
XBI
Total weight of top 15 holdings out of 15
19.71%
ETF 2
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Top 15 holdings
Data as of March 31, 2026
XBI
APELLIS PHARMACEUTICALS
1.83%
ALKERMES
1.45%
MADRIGAL PHARMACEUTICALS INC
1.38%
TG THERAPEUTICS
1.35%
INSMED
1.34%
SCHOLAR ROCK HOLDING CORP
1.30%
US03770N1019
1.28%
PROTAGONIST THERAPEUTICS INC
1.25%
US86627T1088
1.24%
UTD THERAPEUT
1.24%
US74006W2070
1.24%
ARROWHEAD PHARMACEUTICALS INC
1.23%
COGENT BIOSCIENCES
1.22%
BRIDGEBIO PHARMA
1.19%
PTC THERAPEUTI/D
1.18%
ETF 2
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