XBIvsETF 2ETF Comparison
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Choose a second ETF to run a side-by-side ETF comparison with XBI, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XBI performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/22/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XBI ETF 2 | +4.20%– | +10.82%– | +24.76%– | +76.10%– | +83.33%– | +19.73%– |
| Flows | XBI ETF 2 | +$459M– | +$279M– | +$510M– | +$1.45B– | -$425M– | +$1.59B– |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XBI ETF 2 | +30.98%– | +26.78%– | +27.91%– | +32.90%– |
| Max drawdown | XBI ETF 2 | -8.13%– | -9.66%– | -32.94%– | -54.07%– |
| Max drawdown duration | XBI ETF 2 | 13d– | 76d– | 331d– | 1685d– |
Trading data
XBI | ETF 2 | |
Last sale 7/23/2026 at 1:30 PM | $152.23 | – |
| Previous close 07/22/2026 | $152.11 | – |
| Consolidated volume 07/22/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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XBI | ETF 2 | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
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Main metrics
Last update 7/23/2026 at 1:30 PM
Live
Closed
XBI | ETF 2 | |
|---|---|---|
| Last price | $152.23 | – |
| 1D performance | +0.08% | – |
| AuM | $10.24 B | – |
| E/R | 0.35% | – |
Characteristics
XBI | ETF 2 | |
|---|---|---|
| Management strategy | Passive | – |
| Provider | State Street Investment Management | – |
| Benchmark | S&P Biotechnology Select Industry Index | – |
| N° of holdings | 150 | – |
| Asset class | Equities | – |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 31, 2006 | – |
| ESG | No | – |
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Exposure
Countries
XBI
USA
95.06%
Other
4.94%
ETF 2
Sectors
XBI
Healthcare
99.03%
Other
0.97%
ETF 2
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Diversification
XBI
Total weight of top 15 holdings out of 15
19.19%
ETF 2
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Top 15 holdings
Data as of June 30, 2026
XBI
Apogee Therapeutics, Inc.
1.48%
Moderna, Inc.
1.41%
Twist Bioscience Corp.
1.40%
Oruka Therapeutics, Inc.
1.37%
Kymera Therapeutics, Inc.
1.35%
Viking Therapeutics, Inc.
1.30%
Praxis Precision Medicines, Inc.
1.29%
Erasca, Inc.
1.27%
Revolution Medicines, Inc.
1.20%
Rhythm Pharmaceuticals, Inc.
1.20%
CG Oncology, Inc.
1.20%
SELLAS Life Sciences Group, Inc.
1.19%
Vaxcyte, Inc.
1.18%
Dianthus Therapeutics, Inc.
1.18%
Cytokinetics, Inc.
1.17%
ETF 2
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Latest news about XBI
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