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XBI
US Health Care
Passive
NYSE listed

State Street SPDR S&P Biotech ETF

This ETF provides exposure to Equally Weighted US Biotechnology Equities

XBI performance and flow charts

Last update 7/23/2026 at 1:30 PM
Live
Closed
Last price
$152.23
+$0.12 (+0.08%) Today

Performance

024681012%Jun 22Jun 29Jul 7Jul 14Jul 21

Flows

0 M200 M400 M600 M800 M
1 day price range
$149.33
$153.38
52 week price range
$85.20
$164.25
1W perf
-2.69%
YTD perf
+24.76%
YTD flows
+$510M
AuM
$10.24B
E/R
0.35%
TTM yield
0.38%
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Historic performance and flows

Data as of July 22, 2026
1M3MYTD1Y3Y5Y
Perf.+4.20%+10.82%+24.76%+76.10%+83.33%+19.73%
Flows+$459M+$279M+$510M+$1.45B-$425M+$1.59B
Data as of July 22, 2026
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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Characteristics

The State Street SPDR S&P Biotech ETF is built to track the S&P Biotechnology Select Industry Total Return Index - USD. This ETF provides physical exposure - by owning its shares you earn the return of the securities composing the index (as the ETF holds them directly). This share class generates a stream of income by distributing dividends.

Management strategyPassive
StrategyLong Only
ProviderState Street Investment Management
N° of holdings153
Replication methodDirect (Physical)
Asset classEquity
Dividend policyDistributing
Trailing 12m distribution yield
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Inception dateJanuary 31, 2006
ESGNo
TrackinsightTrackinsight

More data and info about XBI on Trackinsight

Exposure

Data as of June 30, 2026

Diversification

19.19%

Total weight of top 15 holdings out of 153

Top 15 Holdings

Apogee Therapeutics, Inc.
1.48%
Moderna, Inc.
1.41%
Twist Bioscience Corp.
1.4%
Oruka Therapeutics, Inc.
1.37%
Kymera Therapeutics, Inc.
1.35%
Viking Therapeutics, Inc.
1.3%
Praxis Precision Medicines, Inc.
1.29%
Erasca, Inc.
1.27%
Revolution Medicines, Inc.
1.2%
Rhythm Pharmaceuticals, Inc.
1.2%
CG Oncology, Inc.
1.2%
SELLAS Life Sciences Group, Inc.
1.19%
Vaxcyte, Inc.
1.18%
Dianthus Therapeutics, Inc.
1.18%
Cytokinetics, Inc.
1.17%

Sectors

Healthcare
99.03%
Other
0.97%

Countries

USA
95.06%
Other
4.94%
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Trading data

Last sale
7/23/2026 at 1:30 PM
$152.23
Previous close
$152.11
Consolidated volume
07/22/2026
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Average volume
30 days
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Average discount or premium
30 days
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Average Bid/Ask spread
30 days
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Volatility and drawdown

3M1Y3Y5Y
Volatility+30.98%+26.78%+27.91%+32.90%
Max drawdown
-8.13%-9.66%-32.94%-54.07%
Max drawdown duration
13d76d331d1685d
Time to recover
N/A10d183d1435d

Replication quality

Data as of June 30, 2026
1-year trailing difference

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Tracking error
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Tracking difference
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1 year cumulative return difference
Best
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Worst
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daily return difference
Average
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Worst
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Frequently asked questions about XBI

What type of ETF is XBI?

XBI is a Passive ETF that provides exposure to Equity assets. It is managed by State Street Investment Management.

What index does XBI track?

XBI tracks the S&P Biotechnology Select Industry Total Return Index - USD, aiming to replicate its performance through full replication.

What does XBI invest in?

This ETF provides exposure to Equally Weighted US Biotechnology Equities. It is part of the segment: US Health Care.

What is the expense ratio of XBI?

The total expense ratio (TER) of XBI is 0.35%, representing the annual fee charged by the fund manager.

When was XBI launched?

XBI was launched on January 31, 2006, marking its entry into the ETF market.

Who is the issuer of XBI?

XBI is issued by State Street Investment Management.

What is the AUM of XBI?

As of July 22, 2026, XBI manages $10.24 B, reflecting the total assets held in the fund.

How has XBI performed recently?

As of July 22, 2026, XBI delivered a return of 4.2% over the past month (1M performance), 10.82% over the past three months (3M), and 24.76% year-to-date (YTD).

What are the recent fund flows for XBI?

As of July 22, 2026, XBI has seen net flows of +$459M in the past month (1M flow) and +$510M year-to-date (YTD).

Does XBI pay dividends?

As of July 22, 2026, XBI has a trailing 12-month distribution yield of 0.38%.

How many holdings are in XBI

As of June 30, 2026, XBI holds 153 securities in its portfolio. This level of diversification can influence the fund’s risk profile and exposure to individual assets.

How diversified is XBI?

As of June 30, 2026, XBI holds 153 securities, with 19.19% of its assets concentrated in its top 15 holdings.

What are the top holdings of XBI?

As of June 30, 2026, XBI holds a portfolio of 153 underlyings, with its largest positions including Apogee Therapeutics, Inc., Moderna, Inc. and Twist Bioscience Corp.. These top holdings play a significant role in shaping the fund’s performance and exposure.

What countries or regions does XBI invest in?

As of June 30, 2026, XBI has its largest geographic exposures in USA.

What sectors or themes does XBI focus on?

As of June 30, 2026, XBI is primarily exposed to Healthcare.

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