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XBI
Passive ETF
NYSE

SPDR S&P Biotech ETF

This ETF provides exposure to Equally Weighted US Biotechnology Equities Read more

Passive ETF
Last update 3/11/2026 at 1:30 PM
Live
Closed
This fund is part of
US Health Care
-0.51%
Last Price
$126.38
% Change
-0.82%
1W flows
-$40M
1m flows
-$21M
AuM
$8.06B
E/R
0.35%
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Trading data

Last sale
3/11/2026 at 1:30 PM
$126.38
Previous close
$127.43
Consolidated volume
03/10/2026
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Average volume
30 days
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Average discount or premium
30 days
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Average Bid/Ask spread
30 days
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XBI performance and flow charts

Performance

-2.0-1.00.01.02.03.0%Feb 10Feb 18Feb 25Mar 4

Flows

-200 M0 M200 M400 M600 M800 M

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows

Data as of March 10, 2026
1M3MYTD1Y3Y5Y
Perf.+1.75%+4.75%+4.50%+48.40%+69.29%-9.32%
Flows-$21M-$262M-$163M-$25M-$1.83B+$1.19B
Data as of March 10, 2026

Volatility and drawdown

3M1Y3Y5Y
Volatility+25.66%+28.03%+27.31%+32.96%
Max drawdown
-8.19%-21.44%-32.94%-57.63%
Max drawdown duration
47d141d331d1821d
Time to recover
N/A127d183dN/A

Replication quality

Data as of February 27, 2026
1-year trailing difference

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Tracking error
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Tracking difference
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1 year cumulative return difference
Best
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Worst
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daily return difference
Average
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Worst
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Exposure

Data as of January 31, 2026

Countries

USA
94.51%
Other
5.49%

Sectors

Health Care
88.03%
Other
11.97%

Diversification

Total weight of top 15 holdings out of 149

21.6%

Top 15 Holdings

MODERNA INC
1.85%
MIRUM PHARMACEUTICALS INC
1.58%
REVOLUTION MEDICINES INC
1.52%
VAXCYTE
1.5%
AMICUS THERAPEUTICS
1.48%
US74006W2070
1.46%
ALKERMES
1.44%
GILEAD SCIENCES
1.43%
KRYSTAL BIOTECH INC
1.42%
HALOZYME THERAPEUTICS
1.4%
AMGEN-T
1.32%
CELCUITY INC
1.31%
ROIVANT SCIENCES LTD
1.3%
BRIDGEBIO PHARMA
1.3%
VERTEX PHARMACEUTICALS
1.29%

Characteristics

The SPDR S&P Biotech ETF is built to track the S&P Biotechnology Select Industry Total Return Index - USD. This ETF provides physical exposure - by owning its shares you earn the return of the securities composing the index (as the ETF holds them directly).

This share class generates a stream of income by distributing dividends.

Management strategyPassive
ProviderSPDR
N° of holdings149
Replication methodDirect (Physical)
Asset classEquities
Dividend policyDistributing
Trailing 12m distribution yield
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Inception dateJanuary 31, 2006
ESGNo

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Frequently asked questions about XBI

What type of ETF is XBI?

XBI is a Passive ETF that provides exposure to Equity assets. It is managed by SPDR.

What index does XBI track?

XBI tracks the S&P Biotechnology Select Industry Total Return Index - USD, aiming to replicate its performance through full replication.

What does XBI invest in?

This ETF provides exposure to Equally Weighted US Biotechnology Equities. It is part of the segment: US Health Care.

What is the expense ratio of XBI?

The total expense ratio (TER) of XBI is 0.35%, representing the annual fee charged by the fund manager.

When was XBI launched?

XBI was launched on January 31, 2006, marking its entry into the ETF market.

Who is the issuer of XBI?

XBI is issued by SPDR.

What is the AUM of XBI?

As of March 10, 2026, XBI manages $8.06 B, reflecting the total assets held in the fund.

How has XBI performed recently?

As of March 10, 2026, XBI delivered a return of 1.75% over the past month (1M performance), 4.75% over the past three months (3M), and 4.5% year-to-date (YTD).

What are the recent fund flows for XBI?

As of March 10, 2026, XBI has seen net flows of -$21M in the past month (1M flow) and -$163M year-to-date (YTD).

Does XBI pay dividends?

As of March 10, 2026, XBI has a trailing 12-month distribution yield of 0.35%.

How many holdings are in XBI

As of January 31, 2026, XBI holds 149 securities in its portfolio. This level of diversification can influence the fund’s risk profile and exposure to individual assets.

How diversified is XBI?

As of January 31, 2026, XBI holds 149 securities, with 21.6% of its assets concentrated in its top 15 holdings.

What are the top holdings of XBI?

As of January 31, 2026, XBI holds a portfolio of 149 underlyings, with its largest positions including MODERNA INC, MIRUM PHARMACEUTICALS INC and REVOLUTION MEDICINES INC. These top holdings play a significant role in shaping the fund’s performance and exposure.

What countries or regions does XBI invest in?

As of January 31, 2026, XBI has its largest geographic exposures in USA.

What sectors or themes does XBI focus on?

As of January 31, 2026, XBI is primarily exposed to Health Care.

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