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XBIvsPSCHETF Comparison
SPDR S&P Biotech ETF (XBI) and Invesco S&P SmallCap Health Care ETF (PSCH) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. XBI is more expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.29% for PSCH. XBI is up 3.65% year-to-date (YTD) with -$59M in YTD flows. PSCH performs worse with -6.58% YTD performance, and -$14M in YTD flows. Run a side-by-side ETF comparison of XBI and PSCH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
XBI vs PSCH performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XBI PSCH | +1.38%-4.72% | +3.11%-11.03% | +3.65%-6.58% | +47.21%-2.86% | +63.16%-2.42% | -13.71%-34.70% |
| Flows | XBI PSCH | -$4M-$12M | -$179M-$15M | -$59M-$14M | +$90M-$33M | -$1.64B-$168M | +$1.20B-$230M |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XBI PSCH | +25.68%+18.03% | +28.04%+23.00% | +27.26%+21.45% | +32.91%+22.75% |
| Max drawdown | XBI PSCH | -8.19%-11.08% | -21.44%-13.37% | -32.94%-23.50% | -57.63%-47.23% |
| Max drawdown duration | XBI PSCH | 48d79d | 141d242d | 331d449d | 1822d1718d |
XBI | PSCH | |
Last sale 3/11/2026 at 1:30 PM | $126.38 | $41.15 |
| Previous close 03/11/2026 | $127.43 | $41.39 |
| Consolidated volume 03/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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XBI | PSCH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
XBI | PSCH | |
|---|---|---|
| Last price | $126.38 | $41.15 |
| 1D performance | -0.82% | -0.58% |
| AuM | $8.10 B | $124.38 M |
| E/R | 0.35% | 0.29% |
Countries
Sectors
Diversification
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
Top 15 holdings
How have the XBI and PSCH ETFs performed in 2026?
As of March 11, 2026, XBI is up 3.65% year-to-date (YTD), while PSCH has lost -6.58%. That puts XBI better performer ahead so far this year.
Which ETF is attracting more investor money: XBI or PSCH?
Year-to-date, the XBI ETF saw -$59M in flows, compared to -$14M for PSCH.
Which ETF is more volatile: XBI or PSCH?
Over the past year, XBI had a volatility of 28.04%, while PSCH experienced 23%.
Which ETF is bigger: XBI or PSCH?
As of March 11, 2026, XBI holds $8.10 B in assets under management (AUM), while PSCH manages $124.38 M.
What sectors do the XBI and PSCH ETFs invest in?
XBI leans toward sectors like Health Care. Meanwhile, PSCH focuses on Health Care.
What are the top holdings of the XBI ETF and PSCH ETF?
XBI top holdings include MODERNA INC, MIRUM PHARMACEUTICALS INC and REVOLUTION MEDICINES INC. PSCH holds in its top three: ARROWHEAD PHARMACEUTICALS INC, KRYSTAL BIOTECH INC and GLAUKOS.
Which ETF is more diversified: XBI or PSCH?
XBI holds 149 securities with 21.6% of its assets in the top 15. PSCH has 75 securities and a top 15 weight of 43.5%.
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