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SPDR S&P Biotech ETF (XBI) and Invesco DWA Healthcare Momentum ETF (PTH) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. XBI is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.72% for PTH. XBI is up 3.65% year-to-date (YTD) with -$59M in YTD flows. PTH performs worse with -1.66% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of XBI and PTH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XBI PTH | +1.38%-0.00% | +3.11%-3.57% | +3.65%-1.66% | +47.21%+29.38% | +63.16%+33.57% | -13.71%-9.43% |
| Flows | XBI PTH | -$4M- | -$179M-$2M | -$59M-$2M | +$90M-$12M | -$1.64B-$92M | +$1.20B-$490M |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XBI PTH | +25.68%+21.18% | +28.04%+24.52% | +27.26%+24.28% | +32.91%+25.52% |
| Max drawdown | XBI PTH | -8.19%-7.58% | -21.44%-16.12% | -32.94%-29.24% | -57.63%-50.10% |
| Max drawdown duration | XBI PTH | 48d87d | 141d183d | 331d271d | 1822d1651d |
XBI | PTH | |
Last sale 3/12/2026 at 2:09 PM | $124.15 | $48.80 |
| Previous close 03/11/2026 | $126.38 | $49.20 |
| Consolidated volume 03/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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XBI | PTH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
XBI | PTH | |
|---|---|---|
| Last price | $124.15 | $48.80 |
| 1D performance | -1.76% | -0.81% |
| AuM | $8.10 B | $121.25 M |
| E/R | 0.35% | 0.72% |
XBI | PTH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | SPDR | Invesco |
| Benchmark | S&P Biotechnology Select Industry Index | Dorsey Wright Healthcare Technical Leaders Index |
| N° of holdings | 123 | 46 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 31, 2006 | October 12, 2006 |
| ESG | No | No |
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
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