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SPDR S&P Biotech ETF (XBI) belongs to the US Health Care segment. ARK Genomic Revolution ETF (ARKG) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. XBI is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.75% for ARKG. XBI is up 3.65% year-to-date (YTD) with -$59M in YTD flows. ARKG performs worse with -4.22% YTD performance, and -$14M in YTD flows. Run a side-by-side ETF comparison of XBI and ARKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XBI ARKG | +1.38%-3.97% | +3.11%-10.24% | +3.65%-4.22% | +47.21%+27.40% | +63.16%+1.75% | -13.71%-68.08% |
| Flows | XBI ARKG | -$4M-$69M | -$179M-$81M | -$59M-$14M | +$90M-$206M | -$1.64B-$635M | +$1.20B-$2.75B |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XBI ARKG | +25.68%+39.15% | +28.04%+44.66% | +27.26%+42.31% | +32.91%+45.26% |
| Max drawdown | XBI ARKG | -8.19%-19.50% | -21.44%-23.94% | -32.94%-51.98% | -57.63%-80.33% |
| Max drawdown duration | XBI ARKG | 48d47d | 141d77d | 331d965d | 1822d1821d |
XBI | ARKG | |
Last sale 3/12/2026 at 1:30 PM | $122.64 | $26.17 |
| Previous close 03/11/2026 | $126.38 | $27.67 |
| Consolidated volume 03/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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XBI | ARKG | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
XBI | ARKG | |
|---|---|---|
| Last price | $122.64 | $26.17 |
| 1D performance | -2.96% | -5.42% |
| AuM | $8.10 B | $1.11 B |
| E/R | 0.35% | 0.75% |
XBI | ARKG | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | SPDR | Ark Investment |
| Benchmark | S&P Biotechnology Select Industry Index | - |
| N° of holdings | 123 | 30 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 31, 2006 | April 2, 2019 |
| ESG | No | No |
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
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