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XLVvsXBIETF Comparison

ETF 1

XLV

State Street Health Care Select Sector SPDR ETF

This fund is part of

US Health Care

+1.78%

Full XLV fund page

VS

ETF 2

XBI

State Street SPDR S&P Biotech ETF

This fund is part of

US Health Care

+1.78%

Full XBI fund page

State Street Health Care Select Sector SPDR ETF (XLV) and State Street SPDR S&P Biotech ETF (XBI) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. XLV is less expensive with a Total Expense Ratio (TER) of 0.08%, versus 0.35% for XBI. XLV is down -2.94% year-to-date (YTD) with +$877M in YTD flows. XBI performs better with 7.05% YTD performance, and -$40M in YTD flows. Run a side-by-side ETF comparison of XLV and XBI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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XLV vs XBI performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 04/08/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	XLV XBI	-2.64%+2.75%	-5.03%+5.58%	-2.94%+7.05%	+14.42%+87.74%	+17.81%+72.37%	+39.01%-1.10%
Flows	XLV XBI	-$299M-$32M	+$36M-$399M	+$877M-$40M	+$442M+$323M	-$4.43B-$1.37B	+$7.10B+$1.35B

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	XLV XBI	+14.94%+30.48%	+16.81%+27.49%	+13.67%+27.63%	+14.56%+32.76%
Max drawdown	XLV XBI	-10.19%-9.66%	-10.19%-9.66%	-17.05%-32.94%	-17.05%-55.10%
Max drawdown duration	XLV XBI	38d76d	38d76d	444d331d	444d1806d

Trading data

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	XLV	XBI
Last sale 4/9/2026 at 1:30 PM	$149.31	$131.82
Previous close 04/08/2026	$149.67	$130.65
Consolidated volume 04/08/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of March 31, 2026

1-year trailing difference

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	XLV	XBI
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 4/9/2026 at 1:30 PM

Live

Closed

	XLV	XBI
Last price	$149.31	$131.82
1D performance	-0.24%	+0.90%
AuM	$39.19 B	$8.32 B
E/R	0.08%	0.35%

Characteristics

	XLV	XBI
Management strategy	Passive	Passive
Provider	SPDR	SPDR
Benchmark	S&P Health Care Select Sector Index	S&P Biotechnology Select Industry Index
N° of holdings	57	121
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	December 16, 1998	January 31, 2006
ESG	No	No

More XLV data on Trackinsight

More XBI data on Trackinsight

Exposure

Countries

XLV

USA

97.21%

Other

2.79%

XBI

USA

93.09%

Other

6.91%

Sectors

XLV

Health Care

98.24%

Other

1.76%

XBI

Health Care

87.1%

Other

12.9%

Diversification

XLV

Total weight of top 15 holdings out of 15

70.09%

XBI

Total weight of top 15 holdings out of 15

22.98%

Top 15 holdings

Data as of February 28, 2026

XLV

LILLY

14.41%

JOHNSON&JOHNSON

10.32%

ABBVIE

7.07%

MERCK & CO INC

5.30%

UNITEDHEALTH GRP

4.58%

AMGEN-T

3.61%

ABBOTT LABS

3.49%

THERMO FISHER SCIENTIFIC

3.38%

GILEAD SCIENCES

3.19%

INTUITIVE SURGICAL

3.08%

PFIZER

2.71%

STRYKER

2.30%

DANAHER

2.28%

BRISTOL-MYERS SQUIBB

2.19%

VERTEX PHARMACEUTICALS

2.17%

XBI

MODERNA INC

2.22%

ROIVANT SCIENCES LTD

1.72%

VAXCYTE

1.71%

ARCELLX

1.64%

REVOLUTION MEDICINES INC

1.58%

US74006W2070

1.55%

AMGEN-T

1.48%

GILEAD SCIENCES

1.48%

AMICUS THERAPEUTICS

1.46%

MIRUM PHARMACEUTICALS INC

1.39%

KRYSTAL BIOTECH INC

1.38%

BIOMARIN PHARMACEUTICAL

1.38%

VERTEX PHARMACEUTICALS

1.34%

HALOZYME THERAPEUTICS

1.33%

CELCUITY INC

1.32%

Frequently asked questions about XLV and XBI

XLVvsXBIETF Comparison

State Street Health Care Select Sector SPDR ETF

State Street SPDR S&P Biotech ETF

XLV vs XBI performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the XLV and XBI ETFs performed in 2026?

As of April 8, 2026, XLV is down -2.94% year-to-date (YTD), while XBI has returned 7.05%. That puts XBI better performer ahead so far this year.

Which ETF is attracting more investor money: XLV or XBI?

Year-to-date, the XLV ETF saw +$877M in flows, compared to -$40M for XBI.

Which ETF is more volatile: XLV or XBI?

Over the past year, XLV had a volatility of 16.81%, while XBI experienced 27.49%.

Which ETF is bigger: XLV or XBI?

As of April 8, 2026, XLV holds $39.19 B in assets under management (AUM), while XBI manages $8.32 B.

What sectors do the XLV and XBI ETFs invest in?

XLV leans toward sectors like Health Care. Meanwhile, XBI focuses on Health Care.

What are the top holdings of the XLV ETF and XBI ETF?

XLV top holdings include LILLY, JOHNSON&JOHNSON and ABBVIE. XBI holds in its top three: MODERNA INC, ROIVANT SCIENCES LTD and VAXCYTE.

Which ETF is more diversified: XLV or XBI?

XLV holds 60 securities with 70.09% of its assets in the top 15. XBI has 147 securities and a top 15 weight of 22.98%.

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