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ALPS Medical Breakthroughs ETF
SBIO performance and flow charts
Performance
Flows
Historic performance and flows
Data as of September 10, 2026| 1M | 3M | YTD | 1Y | 3Y | 5Y | |
|---|---|---|---|---|---|---|
| Perf. | -4.73% | +26.53% | +24.90% | +75.78% | +121.32% | +43.40% |
| Flows | +$31M | +$51M | +$75M | +$84M | +$56M | +$17M |
Characteristics
The ALPS Medical Breakthroughs ETF is built to track the S-Network Medical Breakthroughs Index NTR - USD. This ETF provides physical exposure - by owning its shares you earn the return of the securities composing the index (as the ETF holds them directly). This share class generates a stream of income by distributing dividends.
| Management strategy | Passive |
| Strategy | Long Only |
| Provider | ALPS |
| N° of holdings | 104 |
| Replication method | Direct (Physical) |
| Asset class | Equity |
| Dividend policy | Distributing |
Trailing 12m distribution yield | Join for free |
| Inception date | December 30, 2014 |
| ESG | No |
More data and info about SBIO on Trackinsight
Exposure
Data as of July 31, 2026Diversification
Total weight of top 15 holdings out of 104
Top 15 Holdings
Sectors
Countries
Similar ETFs
Trading data
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | |
|---|---|---|---|---|
| Volatility | +32.19% | +30.94% | +31.10% | +33.90% |
Max drawdown | -9.65% | -12.63% | -42.12% | -52.50% |
Max drawdown duration | 22d | 60d | 331d | 1479d |
Time to recover | N/A | 11d | 184d | 757d |
Replication quality
Data as of August 31, 2026Create an account to view replication metrics
1 year cumulative return difference | |
|---|---|
| Best | Join for free |
| Worst | Join for free |
| daily return difference | |
|---|---|
| Average | Join for free |
| Worst | Join for free |
What type of ETF is SBIO?
SBIO is a Passive ETF that provides exposure to Equity assets. It is managed by ALPS.
What index does SBIO track?
SBIO tracks the S-Network Medical Breakthroughs Index NTR - USD, aiming to replicate its performance through full replication.
What does SBIO invest in?
This ETF provides exposure to Mid and Small-Cap US Equities. It is part of the segment: Tomorrow's Treatments.
What is the expense ratio of SBIO?
The total expense ratio (TER) of SBIO is 0.5%, representing the annual fee charged by the fund manager.
When was SBIO launched?
SBIO was launched on December 30, 2014, marking its entry into the ETF market.
Who is the issuer of SBIO?
SBIO is issued by ALPS.
What is the AUM of SBIO?
As of September 10, 2026, SBIO manages $234.69 M, reflecting the total assets held in the fund.
How has SBIO performed recently?
As of September 10, 2026, SBIO delivered a return of -4.73% over the past month (1M performance), 26.53% over the past three months (3M), and 24.9% year-to-date (YTD).
What are the recent fund flows for SBIO?
As of September 10, 2026, SBIO has seen net flows of +$31M in the past month (1M flow) and +$75M year-to-date (YTD).
How many holdings are in SBIO
As of July 31, 2026, SBIO holds 104 securities in its portfolio. This level of diversification can influence the fund’s risk profile and exposure to individual assets.
How diversified is SBIO?
As of July 31, 2026, SBIO holds 104 securities, with 42.78% of its assets concentrated in its top 15 holdings.
What are the top holdings of SBIO?
As of July 31, 2026, SBIO holds a portfolio of 104 underlyings, with its largest positions including Crinetics Pharmaceuticals, Inc., Apogee Therapeutics, Inc. and CG Oncology, Inc.. These top holdings play a significant role in shaping the fund’s performance and exposure.
What countries or regions does SBIO invest in?
As of July 31, 2026, SBIO has its largest geographic exposures in USA.
What sectors or themes does SBIO focus on?
As of July 31, 2026, SBIO is primarily exposed to Healthcare.
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