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XLVvsXLVIETF Comparison

ETF 1
XLV

State Street Health Care Select Sector SPDR ETF

This fund is part of
US Health Care
-0.51%
Full XLV fund page
VS
ETF 2
XLVI

The Health Care Select Sector SPDR Premium Income Fund

This fund is part of
Options Strategies
-0.11%
Full XLVI fund page

State Street Health Care Select Sector SPDR ETF (XLV) belongs to the US Health Care segment. The Health Care Select Sector SPDR Premium Income Fund (XLVI) is part of the Options Strategies segment. Both ETFs have the same top 3 sector exposures: and Health Care. XLV is less expensive with a Total Expense Ratio (TER) of 0.08%, versus 0.35% for XLVI. XLV is down -1.03% year-to-date (YTD) with +$1.01B in YTD flows. XLVI performs better with 0.43% YTD performance, and +$2M in YTD flows. Run a side-by-side ETF comparison of XLV and XLVI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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XLV vs XLVI performance and flow charts

Performance

-2.0-1.00.01.02.03.0%Feb 10Feb 18Feb 25Mar 4

Cumulative Flows

-800,000,000-600,000,000-400,000,000-200,000,0000200,000,000Feb 10Feb 18Feb 25Mar 4

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/10/2026
1M3MYTD1Y3Y5Y
Perf.
XLV
XLVI
-1.40%-0.34%
+1.13%+2.91%
-1.03%+0.43%
+5.51%n/a
+29.64%n/a
+45.96%n/a
Flows
XLV
XLVI
-$720M+$788K
+$376M+$3M
+$1.01B+$2M
+$304M-
-$4.79B-
+$7.07B-
Volatility and drawdown
3M1Y3Y5Y
Volatility
XLV
XLVI
+13.70%+10.28%
+17.44%n/a
+13.60%n/a
+14.47%n/a
Max drawdown
XLV
XLVI
-4.63%-3.26%
-12.44%n/a
-17.05%n/a
-17.05%n/a
Max drawdown duration
XLV
XLVI
9d9d
225dn/a
444dn/a
444dn/a
Trading data

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XLV
XLVI
Last sale
3/11/2026 at 1:30 PM
$152.85
$25.92
Previous close
03/10/2026
$153.15
$25.98
Consolidated volume
03/10/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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XLVI
is actively managed and doesn’t replicate an index

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XLV
XLVI
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/11/2026 at 1:30 PM
Live
Closed
XLV
XLVI
Last price
$152.85
$25.92
1D performance
-0.20%
-0.23%
AuM$40.26 B$13.26 M
E/R0.08%0.35%
Characteristics
XLV
XLVI
Management strategyPassiveActive
ProviderSPDRSPDR
BenchmarkS&P Health Care Select Sector Index-
N° of holdings5757
Asset classEquities-
Trailing 12m distribution yield
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Inception dateDecember 16, 1998July 30, 2025
ESGNoNo
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Exposure

Countries

XLV
USA
96.98%
Other
3.02%
XLVI
USA
96.37%
Other
3.63%

Sectors

XLV
Health Care
98.26%
Other
1.74%
XLVI
Health Care
97.65%
Other
2.35%
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Diversification

XLV

Total weight of top 15 holdings out of 15

70.12%
XLVI

Total weight of top 15 holdings out of 15

69.69%

Top 15 holdings

Data as of January 31, 2026
XLV
LILLY
14.69%
JOHNSON&JOHNSON
9.77%
ABBVIE
7.03%
MERCK & CO INC
4.88%
UNITEDHEALTH GRP
4.64%
THERMO FISHER SCIENTIFIC
3.88%
ABBOTT LABS
3.39%
AMGEN-T
3.28%
INTUITIVE SURGICAL
3.19%
GILEAD SCIENCES
3.14%
PFIZER
2.68%
BOSTON SCIENTIFIC
2.47%
DANAHER
2.45%
MEDTRONIC PLC
2.36%
STRYKER
2.27%
XLVI
LILLY
14.60%
JOHNSON&JOHNSON
9.71%
ABBVIE
6.99%
MERCK & CO INC
4.85%
UNITEDHEALTH GRP
4.61%
THERMO FISHER SCIENTIFIC
3.85%
ABBOTT LABS
3.37%
AMGEN-T
3.26%
INTUITIVE SURGICAL
3.17%
GILEAD SCIENCES
3.12%
PFIZER
2.66%
BOSTON SCIENTIFIC
2.46%
DANAHER
2.44%
MEDTRONIC PLC
2.34%
STRYKER
2.25%
Frequently asked questions about XLV and XLVI

How have the XLV and XLVI ETFs performed in 2026?

As of March 10, 2026, XLV is down -1.03% year-to-date (YTD), while XLVI has returned 0.43%. That puts XLVI better performer ahead so far this year.

Which ETF is attracting more investor money: XLV or XLVI?

Year-to-date, the XLV ETF saw +$1.01B in flows, compared to +$2M for XLVI.

Which ETF is bigger: XLV or XLVI?

As of March 10, 2026, XLV holds $40.26 B in assets under management (AUM), while XLVI manages $13.26 M.

What sectors do the XLV and XLVI ETFs invest in?

XLV leans toward sectors like Health Care. Meanwhile, XLVI focuses on Health Care.

What are the top holdings of the XLV ETF and XLVI ETF?

XLV top holdings include LILLY, JOHNSON&JOHNSON and ABBVIE. XLVI holds in its top three: LILLY, JOHNSON&JOHNSON and ABBVIE.

Which ETF is more diversified: XLV or XLVI?

XLV holds 60 securities with 70.12% of its assets in the top 15. XLVI has 60 securities and a top 15 weight of 69.69%.

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