XHSvsXBIETF Comparison
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State Street SPDR S&P Health Care Services ETF (XHS) and State Street SPDR S&P Biotech ETF (XBI) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. Both XHS and XBI have the same Total Expense Ratio (TER) of 0.35%. XHS is up 1.76% year-to-date (YTD) with +$9M in YTD flows. XBI performs better with 9.28% YTD performance, and -$19M in YTD flows. Run a side-by-side ETF comparison of XHS and XBI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XHS vs XBI performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XHS XBI | +7.11%+11.52% | -2.43%+4.22% | +1.76%+9.28% | +14.80%+65.29% | +21.34%+64.93% | -0.83%-3.74% |
| Flows | XHS XBI | +$1M+$314M | -$5M-$560M | +$9M-$19M | -$3M+$404M | -$30M-$1.15B | -$34M+$839M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XHS XBI | +18.84%+30.22% | +17.87%+25.87% | +18.09%+27.40% | +21.14%+32.69% |
| Max drawdown | XHS XBI | -11.77%-7.98% | -12.54%-9.66% | -17.78%-32.94% | -32.53%-55.10% |
| Max drawdown duration | XHS XBI | 88d42d | 128d76d | 362d331d | 1761d1822d |
Trading data
XHS | XBI | |
Last sale 4/24/2026 at 7:59 PM | $108.86 | $134.28 |
| Previous close 04/24/2026 | $107.79 | $133.28 |
| Consolidated volume 04/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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XHS | XBI | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/24/2026 at 7:59 PM
Live
Closed
XHS | XBI | |
|---|---|---|
| Last price | $108.86 | $134.28 |
| 1D performance | +0.99% | +0.75% |
| AuM | $93.51 M | $8.52 B |
| E/R | 0.35% | 0.35% |
Characteristics
XHS | XBI | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | State Street Investment Management | State Street Investment Management |
| Benchmark | S&P Health Care Services Select Industry Index | S&P Biotechnology Select Industry Index |
| N° of holdings | 51 | 122 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | September 28, 2011 | January 31, 2006 |
| ESG | No | No |
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Exposure
Countries
XHS
USA
99.89%
Other
0.11%
XBI
USA
95.16%
Other
4.84%
Sectors
XHS
Health Care
86.56%
Other
13.44%
XBI
Health Care
86.79%
Other
13.21%
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Diversification
XHS
Total weight of top 15 holdings out of 15
30.62%
XBI
Total weight of top 15 holdings out of 15
19.71%
Top 15 holdings
Data as of March 31, 2026
XHS
MEDNAX
2.18%
HEALTHEQUITY I/D
2.15%
GUARDANT HEALTH INC
2.12%
CORVEL
2.08%
US10950A1060
2.08%
CIGNA
2.06%
HUMANA
2.05%
ELEVANCE HEALTH INC
2.04%
DAVITA INC
2.00%
US5049221055
1.99%
ACADIA HEALTHCARE COMPANY
1.98%
CARDINAL HEALTH
1.98%
ALIGNMENT HEALTHCARE
1.98%
QUEST DIAGNOSTICS
1.97%
PROGYNY INC
1.96%
XBI
APELLIS PHARMACEUTICALS
1.83%
ALKERMES
1.45%
MADRIGAL PHARMACEUTICALS INC
1.38%
TG THERAPEUTICS
1.35%
INSMED
1.34%
SCHOLAR ROCK HOLDING CORP
1.30%
US03770N1019
1.28%
PROTAGONIST THERAPEUTICS INC
1.25%
US86627T1088
1.24%
UTD THERAPEUT
1.24%
US74006W2070
1.24%
ARROWHEAD PHARMACEUTICALS INC
1.23%
COGENT BIOSCIENCES
1.22%
BRIDGEBIO PHARMA
1.19%
PTC THERAPEUTI/D
1.18%
Frequently asked questions about XHS and XBI
How have the XHS and XBI ETFs performed in 2026?
As of April 24, 2026, XHS is up 1.76% year-to-date (YTD), while XBI has returned 9.28%. That puts XBI better performer ahead so far this year.
Which ETF is attracting more investor money: XHS or XBI?
Year-to-date, the XHS ETF saw +$9M in flows, compared to -$19M for XBI.
Which ETF is more volatile: XHS or XBI?
Over the past year, XHS had a volatility of 17.87%, while XBI experienced 25.87%.
Which ETF is bigger: XHS or XBI?
As of April 24, 2026, XHS holds $93.51 M in assets under management (AUM), while XBI manages $8.52 B.
What sectors do the XHS and XBI ETFs invest in?
XHS leans toward sectors like Health Care. Meanwhile, XBI focuses on Health Care.
What are the top holdings of the XHS ETF and XBI ETF?
XHS top holdings include MEDNAX, HEALTHEQUITY I/D and GUARDANT HEALTH INC. XBI holds in its top three: APELLIS PHARMACEUTICALS, ALKERMES and MADRIGAL PHARMACEUTICALS INC.
Which ETF is more diversified: XHS or XBI?
XHS holds 58 securities with 30.62% of its assets in the top 15. XBI has 151 securities and a top 15 weight of 19.71%.
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