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XHEvsXBIETF Comparison
SPDR S&P Health Care Equipment ETF (XHE) and SPDR S&P Biotech ETF (XBI) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. Both XHE and XBI have the same Total Expense Ratio (TER) of 0.35%. XHE is down -7.18% year-to-date (YTD) with -$4M in YTD flows. XBI performs better with 4.5% YTD performance, and -$163M in YTD flows. Run a side-by-side ETF comparison of XHE and XBI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
XHE vs XBI performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XHE XBI | -5.57%+1.75% | -8.58%+4.75% | -7.18%+4.50% | -2.13%+48.40% | -6.66%+69.29% | -30.59%-9.32% |
| Flows | XHE XBI | --$21M | -$4M-$262M | -$4M-$163M | -$44M-$25M | -$295M-$1.83B | -$430M+$1.19B |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XHE XBI | +18.92%+25.66% | +23.53%+28.03% | +21.08%+27.31% | +24.18%+32.96% |
| Max drawdown | XHE XBI | -12.38%-8.19% | -14.34%-21.44% | -32.63%-32.94% | -49.90%-57.63% |
| Max drawdown duration | XHE XBI | 61d47d | 241d141d | 1052d331d | 1650d1821d |
XHE | XBI | |
Last sale 3/11/2026 at 1:30 PM | $82.04 | $126.38 |
| Previous close 03/10/2026 | $81.73 | $127.43 |
| Consolidated volume 03/10/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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XHE | XBI | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
XHE | XBI | |
|---|---|---|
| Last price | $82.04 | $126.38 |
| 1D performance | +0.38% | -0.82% |
| AuM | $139.06 M | $8.06 B |
| E/R | 0.35% | 0.35% |
XHE | XBI | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | SPDR | SPDR |
| Benchmark | S&P Health Care Equipment Select Industry Index | S&P Biotechnology Select Industry Index |
| N° of holdings | 61 | 123 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 26, 2011 | January 31, 2006 |
| ESG | No | No |
Countries
Sectors
Diversification
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
Top 15 holdings
How have the XHE and XBI ETFs performed in 2026?
As of March 10, 2026, XHE is down -7.18% year-to-date (YTD), while XBI has returned 4.5%. That puts XBI better performer ahead so far this year.
Which ETF is attracting more investor money: XHE or XBI?
Year-to-date, the XHE ETF saw -$4M in flows, compared to -$163M for XBI.
Which ETF is more volatile: XHE or XBI?
Over the past year, XHE had a volatility of 23.53%, while XBI experienced 28.03%.
Which ETF is bigger: XHE or XBI?
As of March 10, 2026, XHE holds $139.06 M in assets under management (AUM), while XBI manages $8.06 B.
What sectors do the XHE and XBI ETFs invest in?
XHE leans toward sectors like Health Care. Meanwhile, XBI focuses on Health Care.
What are the top holdings of the XHE ETF and XBI ETF?
XHE top holdings include NEOGEN, INTEGER HOLDINGS and PENUMBRA. XBI holds in its top three: MODERNA INC, MIRUM PHARMACEUTICALS INC and REVOLUTION MEDICINES INC.
Which ETF is more diversified: XHE or XBI?
XHE holds 64 securities with 30.47% of its assets in the top 15. XBI has 149 securities and a top 15 weight of 21.6%.
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