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VHTvsXLVIETF Comparison

ETF 1
VHT

Vanguard Health Care ETF

This fund is part of
US Health Care
-0.42%
VS
ETF 2
XLVI

State Street Health Care Select Sector SPDR Premium Income Fund

This fund is part of
Options Strategies
-0.25%

Vanguard Health Care ETF (VHT) belongs to the US Health Care segment. State Street Health Care Select Sector SPDR Premium Income Fund (XLVI) is part of the Options Strategies segment. VHT's top 3 sector exposures are Healthcare, Consumer Non-Cyclicals and Business Services. In contrast, XLVI's top sector exposures are Healthcare and Consumer Non-Cyclicals. VHT is less expensive with a Total Expense Ratio (TER) of 0.09%, versus 0.35% for XLVI. VHT is up 9.64% year-to-date (YTD) with +$105M in YTD flows. XLVI performs worse with 6.27% YTD performance, and +$14M in YTD flows. Run a side-by-side ETF comparison of VHT and XLVI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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VHT vs XLVI performance and flow charts

Performance

-4.0-2.00.02.04.0%Aug 10Aug 17Aug 24Aug 31Sep 8

Cumulative Flows

0 M20 M40 M60 M80 MAug 10Aug 17Aug 24Aug 31Sep 8

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Historic performance and flows
Data as of 09/09/2026
1M3MYTD1Y3Y5Y
Perf.
VHT
XLVI
-1.13%-3.23%
+9.33%+4.05%
+9.64%+6.27%
+23.40%+16.84%
+34.65%n/a
+29.09%n/a
Flows
VHT
XLVI
+$89M+$4M
+$388M+$11M
+$105M+$14M
+$333M+$25M
-$2.16B-
-$956M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
VHT
XLVI
+18.32%+11.85%
+15.77%+11.08%
+14.66%n/a
+15.57%n/a
Max drawdown
VHT
XLVI
-4.91%-4.26%
-10.39%-8.21%
-16.88%n/a
-17.77%n/a
Max drawdown duration
VHT
XLVI
21d15d
169d115d
435dn/a
767dn/a
Trading data

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VHT
XLVI
Last sale
9/10/2026 at 5:15 PM
$311.82
$25.78
Previous close
09/09/2026
$313.30
$25.87
Consolidated volume
09/09/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of August 31, 2026
1-year trailing difference

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XLVI
is actively managed and doesn’t replicate an index

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VHT
XLVI
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 9/10/2026 at 5:15 PM
Live
Closed
VHT
XLVI
Last price
$311.82
$25.78
1D performance
-0.47%
-0.35%
AuM$18.95 B$25.61 M
E/R0.09%0.35%
Characteristics
VHT
XLVI
Management strategyPassiveActive
ProviderVanguardState Street Investment Management
BenchmarkMSCI US IMI Health Care 25/50 Index-
N° of holdings41359
Asset classEquities-
Trailing 12m distribution yield
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Inception dateJanuary 26, 2004July 30, 2025
ESGNoNo
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Exposure

Countries

VHT
USA
96.91%
Other
3.09%
XLVI
USA
97.34%
Other
2.66%

Sectors

VHT
Healthcare
97.52%
Other
2.48%
XLVI
Healthcare
97.32%
Other
2.68%
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Diversification

VHT

Total weight of top 15 holdings out of 15

61.16%
XLVI

Total weight of top 15 holdings out of 15

71.63%

Top 15 holdings

Data as of July 31, 2026
VHT
Eli Lilly & Co.
13.37%
Johnson & Johnson
8.83%
AbbVie, Inc.
6.43%
UnitedHealth Group, Inc.
5.45%
Merck & Co., Inc.
4.67%
Thermo Fisher Scientific, Inc.
3.09%
Amgen, Inc.
3.01%
Abbott Laboratories
2.67%
Gilead Sciences, Inc.
2.34%
Pfizer Inc.
2.06%
Bristol Myers Squibb Co.
1.93%
CVS Health Corp.
1.93%
Intuitive Surgical, Inc.
1.82%
Danaher Corp.
1.80%
Vertex Pharmaceuticals, Inc.
1.76%
XLVI
Eli Lilly & Co.
15.45%
Johnson & Johnson
10.49%
AbbVie, Inc.
7.54%
UnitedHealth Group, Inc.
6.40%
Merck & Co., Inc.
5.47%
Thermo Fisher Scientific, Inc.
3.63%
Amgen, Inc.
3.53%
Abbott Laboratories
3.13%
Gilead Sciences, Inc.
2.75%
Pfizer Inc.
2.42%
Bristol Myers Squibb Co.
2.27%
CVS Health Corp.
2.27%
Intuitive Surgical, Inc.
2.13%
Danaher Corp.
2.09%
Vertex Pharmaceuticals, Inc.
2.06%
Frequently asked questions about VHT and XLVI

How have the VHT and XLVI ETFs performed in 2026?

As of September 9, 2026, VHT is up 9.64% year-to-date (YTD), while XLVI has returned 6.27%. That puts VHT better performer ahead so far this year.

Which ETF is attracting more investor money: VHT or XLVI?

Year-to-date, the VHT ETF saw +$105M in flows, compared to +$14M for XLVI.

Which ETF is more volatile: VHT or XLVI?

Over the past year, VHT had a volatility of 15.77%, while XLVI experienced 11.08%.

Which ETF is bigger: VHT or XLVI?

As of September 9, 2026, VHT holds $18.95 B in assets under management (AUM), while XLVI manages $25.61 M.

What sectors do the VHT and XLVI ETFs invest in?

VHT leans toward sectors like Healthcare. Meanwhile, XLVI focuses on Healthcare.

What are the top holdings of the VHT ETF and XLVI ETF?

VHT top holdings include Eli Lilly & Co., Johnson & Johnson and AbbVie, Inc.. XLVI holds in its top three: Eli Lilly & Co., Johnson & Johnson and AbbVie, Inc..

Which ETF is more diversified: VHT or XLVI?

VHT holds 413 securities with 61.16% of its assets in the top 15. XLVI has 59 securities and a top 15 weight of 71.63%.

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