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PTHvsXBIETF Comparison

ETF 1
PTH

Invesco DWA Healthcare Momentum ETF

This fund is part of
US Health Care
-0.51%
Full PTH fund page
VS
ETF 2
XBI

SPDR S&P Biotech ETF

This fund is part of
US Health Care
-0.51%
Full XBI fund page

Invesco DWA Healthcare Momentum ETF (PTH) and SPDR S&P Biotech ETF (XBI) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. PTH is more expensive with a Total Expense Ratio (TER) of 0.72%, versus 0.35% for XBI. PTH is down -0.94% year-to-date (YTD) with -$2M in YTD flows. XBI performs better with 4.5% YTD performance, and -$163M in YTD flows. Run a side-by-side ETF comparison of PTH and XBI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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PTH vs XBI performance and flow charts

Performance

-2.0-1.00.01.02.03.0%Feb 10Feb 18Feb 25Mar 4

Cumulative Flows

-200 M0 M200 M400 M600 M800 MFeb 10Feb 18Feb 25Mar 4

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/10/2026
1M3MYTD1Y3Y5Y
Perf.
PTH
XBI
+0.87%+1.75%
-2.99%+4.75%
-0.94%+4.50%
+31.67%+48.40%
+40.70%+69.29%
-4.17%-9.32%
Flows
PTH
XBI
--$21M
-$2M-$262M
-$2M-$163M
-$15M-$25M
-$92M-$1.83B
-$495M+$1.19B
Volatility and drawdown
3M1Y3Y5Y
Volatility
PTH
XBI
+21.14%+25.66%
+24.53%+28.03%
+24.42%+27.31%
+25.61%+32.96%
Max drawdown
PTH
XBI
-7.58%-8.19%
-16.12%-21.44%
-29.24%-32.94%
-50.10%-57.63%
Max drawdown duration
PTH
XBI
86d47d
183d141d
271d331d
1650d1821d
Trading data

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PTH
XBI
Last sale
3/11/2026 at 1:30 PM
$48.86
$126.38
Previous close
03/10/2026
$49.20
$127.43
Consolidated volume
03/10/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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PTH
XBI
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/11/2026 at 1:30 PM
Live
Closed
PTH
XBI
Last price
$48.86
$126.38
1D performance
-0.70%
-0.82%
AuM$122.13 M$8.06 B
E/R0.72%0.35%
Characteristics
PTH
XBI
Management strategyPassivePassive
ProviderInvescoSPDR
BenchmarkDorsey Wright Healthcare Technical Leaders IndexS&P Biotechnology Select Industry Index
N° of holdings46123
Asset classEquitiesEquities
Trailing 12m distribution yield
Join
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Inception dateOctober 12, 2006January 31, 2006
ESGNoNo
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Exposure

Countries

PTH
USA
95.61%
Other
4.39%
XBI
USA
94.51%
Other
5.49%

Sectors

PTH
Health Care
83.75%
Other
16.25%
XBI
Health Care
88.03%
Other
11.97%
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Diversification

PTH

Total weight of top 15 holdings out of 15

50.37%
XBI

Total weight of top 15 holdings out of 15

21.6%

Top 15 holdings

Data as of January 31, 2026
PTH
US74006W2070
4.89%
GUARDANT HEALTH INC
4.41%
ROIVANT SCIENCES LTD
4.39%
TERNS PHARMACEUTICALS
4.11%
ARROWHEAD PHARMACEUTICALS INC
3.97%
NATERA
3.65%
REVOLUTION MEDICINES INC
3.29%
TENET HEALTHCARE
2.93%
CELCUITY INC
2.90%
MEDPACE HOLDINGS INC
2.86%
AXSOME THERA CMN STK
2.86%
HCA HEALTHCARE
2.71%
UTD THERAPEUT
2.54%
BRIDGEBIO PHARMA
2.49%
COGENT BIOSCIENCES
2.36%
XBI
MODERNA INC
1.85%
MIRUM PHARMACEUTICALS INC
1.58%
REVOLUTION MEDICINES INC
1.52%
VAXCYTE
1.50%
AMICUS THERAPEUTICS
1.48%
US74006W2070
1.46%
ALKERMES
1.44%
GILEAD SCIENCES
1.43%
KRYSTAL BIOTECH INC
1.42%
HALOZYME THERAPEUTICS
1.40%
AMGEN-T
1.32%
CELCUITY INC
1.31%
ROIVANT SCIENCES LTD
1.30%
BRIDGEBIO PHARMA
1.30%
VERTEX PHARMACEUTICALS
1.29%
Frequently asked questions about PTH and XBI

How have the PTH and XBI ETFs performed in 2026?

As of March 10, 2026, PTH is down -0.94% year-to-date (YTD), while XBI has returned 4.5%. That puts XBI better performer ahead so far this year.

Which ETF is attracting more investor money: PTH or XBI?

Year-to-date, the PTH ETF saw -$2M in flows, compared to -$163M for XBI.

Which ETF is more volatile: PTH or XBI?

Over the past year, PTH had a volatility of 24.53%, while XBI experienced 28.03%.

Which ETF is bigger: PTH or XBI?

As of March 10, 2026, PTH holds $122.13 M in assets under management (AUM), while XBI manages $8.06 B.

What sectors do the PTH and XBI ETFs invest in?

PTH leans toward sectors like Health Care. Meanwhile, XBI focuses on Health Care.

What are the top holdings of the PTH ETF and XBI ETF?

PTH top holdings include US74006W2070, GUARDANT HEALTH INC and ROIVANT SCIENCES LTD. XBI holds in its top three: MODERNA INC, MIRUM PHARMACEUTICALS INC and REVOLUTION MEDICINES INC.

Which ETF is more diversified: PTH or XBI?

PTH holds 58 securities with 50.37% of its assets in the top 15. XBI has 149 securities and a top 15 weight of 21.6%.

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