PSCHvsXBIETF Comparison
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Invesco S&P SmallCap Health Care ETF (PSCH) and State Street SPDR S&P Biotech ETF (XBI) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. PSCH is less expensive with a Total Expense Ratio (TER) of 0.29%, versus 0.35% for XBI. PSCH is up 1.03% year-to-date (YTD) with -$19M in YTD flows. XBI performs better with 9.28% YTD performance, and -$19M in YTD flows. Run a side-by-side ETF comparison of PSCH and XBI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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PSCH vs XBI performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | PSCH XBI | +11.60%+11.52% | -1.82%+4.22% | +1.03%+9.28% | +9.11%+65.29% | -1.19%+64.93% | -29.66%-3.74% |
| Flows | PSCH XBI | -$4M+$314M | -$18M-$560M | -$19M-$19M | -$33M+$404M | -$156M-$1.15B | -$237M+$839M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | PSCH XBI | +23.52%+30.22% | +20.90%+25.87% | +21.73%+27.40% | +22.88%+32.69% |
| Max drawdown | PSCH XBI | -13.58%-7.98% | -15.36%-9.66% | -22.97%-32.94% | -47.23%-55.10% |
| Max drawdown duration | PSCH XBI | 88d42d | 123d76d | 448d331d | 1762d1822d |
Trading data
PSCH | XBI | |
Last sale 4/24/2026 at 1:30 PM | $44.54 | $133.28 |
| Previous close 04/24/2026 | $44.07 | $134.49 |
| Consolidated volume 04/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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PSCH | XBI | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/24/2026 at 1:30 PM
Live
Closed
PSCH | XBI | |
|---|---|---|
| Last price | $44.54 | $133.28 |
| 1D performance | +1.07% | -0.90% |
| AuM | $128.72 M | $8.52 B |
| E/R | 0.29% | 0.35% |
Characteristics
PSCH | XBI | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | Invesco | State Street Investment Management |
| Benchmark | S&P SmallCap 600 Capped Health Care Index | S&P Biotechnology Select Industry Index |
| N° of holdings | 71 | 122 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | April 7, 2010 | January 31, 2006 |
| ESG | No | No |
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Exposure
Countries
PSCH
USA
96.2%
Other
3.8%
XBI
USA
95.16%
Other
4.84%
Sectors
PSCH
Health Care
90.59%
Other
9.41%
XBI
Health Care
86.79%
Other
13.21%
Diversification
PSCH
Total weight of top 15 holdings out of 15
44.68%
XBI
Total weight of top 15 holdings out of 15
19.71%
Top 15 holdings
Data as of March 31, 2026
PSCH
MOLINA HLTHCRE
4.25%
KRYSTAL BIOTECH INC
3.90%
GLAUKOS
3.65%
PROTAGONIST THERAPEUTICS INC
3.58%
US10950A1060
3.45%
PTC THERAPEUTI/D
3.27%
TELEFLEX
3.16%
ALKERMES
2.99%
TG THERAPEUTICS
2.66%
MERIT MEDICAL SYSTEMS
2.51%
RADNET
2.41%
LIGAND PHARMACEUTICALS
2.37%
US45579U1097
2.23%
CORCEPT THERAPEUTICS
2.17%
TRANSMEDICS GROUP
2.08%
XBI
APELLIS PHARMACEUTICALS
1.83%
ALKERMES
1.45%
MADRIGAL PHARMACEUTICALS INC
1.38%
TG THERAPEUTICS
1.35%
INSMED
1.34%
SCHOLAR ROCK HOLDING CORP
1.30%
US03770N1019
1.28%
PROTAGONIST THERAPEUTICS INC
1.25%
US86627T1088
1.24%
UTD THERAPEUT
1.24%
US74006W2070
1.24%
ARROWHEAD PHARMACEUTICALS INC
1.23%
COGENT BIOSCIENCES
1.22%
BRIDGEBIO PHARMA
1.19%
PTC THERAPEUTI/D
1.18%
Frequently asked questions about PSCH and XBI
How have the PSCH and XBI ETFs performed in 2026?
As of April 24, 2026, PSCH is up 1.03% year-to-date (YTD), while XBI has returned 9.28%. That puts XBI better performer ahead so far this year.
Which ETF is attracting more investor money: PSCH or XBI?
Year-to-date, the PSCH ETF saw -$19M in flows, compared to -$19M for XBI.
Which ETF is more volatile: PSCH or XBI?
Over the past year, PSCH had a volatility of 20.9%, while XBI experienced 25.87%.
Which ETF is bigger: PSCH or XBI?
As of April 24, 2026, PSCH holds $128.72 M in assets under management (AUM), while XBI manages $8.52 B.
What sectors do the PSCH and XBI ETFs invest in?
PSCH leans toward sectors like Health Care. Meanwhile, XBI focuses on Health Care.
What are the top holdings of the PSCH ETF and XBI ETF?
PSCH top holdings include MOLINA HLTHCRE, KRYSTAL BIOTECH INC and GLAUKOS. XBI holds in its top three: APELLIS PHARMACEUTICALS, ALKERMES and MADRIGAL PHARMACEUTICALS INC.
Which ETF is more diversified: PSCH or XBI?
PSCH holds 75 securities with 44.68% of its assets in the top 15. XBI has 151 securities and a top 15 weight of 19.71%.
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