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PSCHvsXBIETF Comparison

ETF 1
PSCH

Invesco S&P SmallCap Health Care ETF

This fund is part of
US Health Care
-0.31%
Full PSCH fund page
VS
ETF 2
XBI

SPDR S&P Biotech ETF

This fund is part of
US Health Care
-0.31%
Full XBI fund page

Invesco S&P SmallCap Health Care ETF (PSCH) and SPDR S&P Biotech ETF (XBI) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. PSCH is less expensive with a Total Expense Ratio (TER) of 0.29%, versus 0.35% for XBI. PSCH is down -6.58% year-to-date (YTD) with -$14M in YTD flows. XBI performs better with 3.65% YTD performance, and -$59M in YTD flows. Run a side-by-side ETF comparison of PSCH and XBI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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PSCH vs XBI performance and flow charts

Performance

-4.0-2.00.02.04.0%Feb 11Feb 19Feb 26Mar 5

Cumulative Flows

-400 M-200 M0 M200 M400 M600 M800 MFeb 11Feb 19Feb 26Mar 5

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/11/2026
1M3MYTD1Y3Y5Y
Perf.
PSCH
XBI
-4.72%+1.38%
-11.03%+3.11%
-6.58%+3.65%
-2.86%+47.21%
-2.42%+63.16%
-34.70%-13.71%
Flows
PSCH
XBI
-$12M-$4M
-$15M-$179M
-$14M-$59M
-$33M+$90M
-$168M-$1.64B
-$230M+$1.20B
Volatility and drawdown
3M1Y3Y5Y
Volatility
PSCH
XBI
+18.03%+25.68%
+23.00%+28.04%
+21.45%+27.26%
+22.75%+32.91%
Max drawdown
PSCH
XBI
-11.08%-8.19%
-13.37%-21.44%
-23.50%-32.94%
-47.23%-57.63%
Max drawdown duration
PSCH
XBI
79d48d
242d141d
449d331d
1718d1822d
Trading data

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PSCH
XBI
Last sale
3/12/2026 at 1:30 PM
$39.81
$122.62
Previous close
03/11/2026
$41.15
$126.38
Consolidated volume
03/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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PSCH
XBI
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/12/2026 at 1:30 PM
Live
Closed
PSCH
XBI
Last price
$39.81
$122.62
1D performance
-3.26%
-2.98%
AuM$124.38 M$8.10 B
E/R0.29%0.35%
Characteristics
PSCH
XBI
Management strategyPassivePassive
ProviderInvescoSPDR
BenchmarkS&P SmallCap 600 Capped Health Care IndexS&P Biotechnology Select Industry Index
N° of holdings71123
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateApril 7, 2010January 31, 2006
ESGNoNo
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Exposure

Countries

PSCH
USA
95.98%
Other
4.02%
XBI
USA
94.51%
Other
5.49%

Sectors

PSCH
Health Care
91.17%
Other
8.83%
XBI
Health Care
88.03%
Other
11.97%
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Diversification

PSCH

Total weight of top 15 holdings out of 15

43.5%
XBI

Total weight of top 15 holdings out of 15

21.6%

Top 15 holdings

Data as of January 31, 2026
PSCH
ARROWHEAD PHARMACEUTICALS INC
4.98%
KRYSTAL BIOTECH INC
3.88%
GLAUKOS
3.85%
PTC THERAPEUTI/D
3.30%
ALKERMES
2.95%
RADNET
2.78%
MERIT MEDICAL SYSTEMS
2.64%
PROTAGONIST THERAPEUTICS INC
2.61%
TRANSMEDICS GROUP
2.57%
TELEFLEX
2.48%
US10950A1060
2.46%
CORCEPT THERAPEUTICS
2.31%
US45579U1097
2.26%
TG THERAPEUTICS
2.25%
ADMA BIOLOGICS INC
2.18%
XBI
MODERNA INC
1.85%
MIRUM PHARMACEUTICALS INC
1.58%
REVOLUTION MEDICINES INC
1.52%
VAXCYTE
1.50%
AMICUS THERAPEUTICS
1.48%
US74006W2070
1.46%
ALKERMES
1.44%
GILEAD SCIENCES
1.43%
KRYSTAL BIOTECH INC
1.42%
HALOZYME THERAPEUTICS
1.40%
AMGEN-T
1.32%
CELCUITY INC
1.31%
ROIVANT SCIENCES LTD
1.30%
BRIDGEBIO PHARMA
1.30%
VERTEX PHARMACEUTICALS
1.29%
Frequently asked questions about PSCH and XBI

How have the PSCH and XBI ETFs performed in 2026?

As of March 11, 2026, PSCH is down -6.58% year-to-date (YTD), while XBI has returned 3.65%. That puts XBI better performer ahead so far this year.

Which ETF is attracting more investor money: PSCH or XBI?

Year-to-date, the PSCH ETF saw -$14M in flows, compared to -$59M for XBI.

Which ETF is more volatile: PSCH or XBI?

Over the past year, PSCH had a volatility of 23%, while XBI experienced 28.04%.

Which ETF is bigger: PSCH or XBI?

As of March 11, 2026, PSCH holds $124.38 M in assets under management (AUM), while XBI manages $8.10 B.

What sectors do the PSCH and XBI ETFs invest in?

PSCH leans toward sectors like Health Care. Meanwhile, XBI focuses on Health Care.

What are the top holdings of the PSCH ETF and XBI ETF?

PSCH top holdings include ARROWHEAD PHARMACEUTICALS INC, KRYSTAL BIOTECH INC and GLAUKOS. XBI holds in its top three: MODERNA INC, MIRUM PHARMACEUTICALS INC and REVOLUTION MEDICINES INC.

Which ETF is more diversified: PSCH or XBI?

PSCH holds 75 securities with 43.5% of its assets in the top 15. XBI has 149 securities and a top 15 weight of 21.6%.

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