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GNOMvsXBIETF Comparison
Global X Genomics & Biotechnology ETF - USD (GNOM) belongs to the BioTech & Genomics segment. SPDR S&P Biotech ETF (XBI) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. GNOM is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.35% for XBI. GNOM is down -4.2% year-to-date (YTD) with -$2M in YTD flows. XBI performs better with 0.54% YTD performance, and -$130M in YTD flows. Run a side-by-side ETF comparison of GNOM and XBI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
GNOM vs XBI performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | GNOM XBI | -4.14%-0.44% | -5.72%-0.07% | -4.20%+0.54% | +23.30%+41.14% | -9.06%+58.27% | -52.80%-15.85% |
| Flows | GNOM XBI | --$508M | -$4M-$176M | -$2M-$130M | -$19M-$91M | -$115M-$1.72B | +$11M+$1.46B |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | GNOM XBI | +24.30%+26.44% | +30.21%+28.20% | +28.57%+27.30% | +33.50%+32.93% |
| Max drawdown | GNOM XBI | -13.77%-8.19% | -22.14%-21.44% | -46.50%-32.94% | -72.17%-57.63% |
| Max drawdown duration | GNOM XBI | 49d49d | 113d141d | 1032d331d | 1715d1823d |
GNOM | XBI | |
Last sale 3/12/2026 at 1:30 PM | $43.61 | $122.62 |
| Previous close 03/12/2026 | $45.00 | $126.38 |
| Consolidated volume 03/12/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Create an account to view replication metrics
GNOM | XBI | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
GNOM | XBI | |
|---|---|---|
| Last price | $43.61 | $122.62 |
| 1D performance | -3.09% | -2.98% |
| AuM | $47.76 M | $7.79 B |
| E/R | 0.5% | 0.35% |
Countries
Sectors
Diversification
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
Top 15 holdings
How have the GNOM and XBI ETFs performed in 2026?
As of March 12, 2026, GNOM is down -4.2% year-to-date (YTD), while XBI has returned 0.54%. That puts XBI better performer ahead so far this year.
Which ETF is attracting more investor money: GNOM or XBI?
Year-to-date, the GNOM ETF saw -$2M in flows, compared to -$130M for XBI.
Which ETF is more volatile: GNOM or XBI?
Over the past year, GNOM had a volatility of 30.21%, while XBI experienced 28.2%.
Which ETF is bigger: GNOM or XBI?
As of March 12, 2026, GNOM holds $47.76 M in assets under management (AUM), while XBI manages $7.79 B.
What sectors do the GNOM and XBI ETFs invest in?
GNOM leans toward sectors like Health Care. Meanwhile, XBI focuses on Health Care.
What are the top holdings of the GNOM ETF and XBI ETF?
GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. XBI holds in its top three: MODERNA INC, MIRUM PHARMACEUTICALS INC and REVOLUTION MEDICINES INC.
Which ETF is more diversified: GNOM or XBI?
GNOM holds 48 securities with 63.95% of its assets in the top 15. XBI has 149 securities and a top 15 weight of 21.6%.
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