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BBPvsXBIETF Comparison
Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. SPDR S&P Biotech ETF (XBI) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. BBP is more expensive with a Total Expense Ratio (TER) of 0.79%, versus 0.35% for XBI. BBP is up 5.62% year-to-date (YTD) with +$4M in YTD flows. XBI performs worse with 0.54% YTD performance, and -$130M in YTD flows. Run a side-by-side ETF comparison of BBP and XBI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
BBP vs XBI performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP XBI | +2.73%-0.44% | +7.35%-0.07% | +5.62%+0.54% | +41.19%+41.14% | +72.79%+58.27% | +54.18%-15.85% |
| Flows | BBP XBI | +$4M-$508M | +$16M-$176M | +$4M-$130M | +$19M-$91M | +$19M-$1.72B | +$9M+$1.46B |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP XBI | +24.64%+26.44% | +25.49%+28.20% | +23.37%+27.30% | +26.10%+32.93% |
| Max drawdown | BBP XBI | -7.42%-8.19% | -17.97%-21.44% | -25.54%-32.94% | -38.24%-57.63% |
| Max drawdown duration | BBP XBI | 32d49d | 106d141d | 292d331d | 915d1823d |
BBP | XBI | |
Last sale 3/13/2026 at 1:30 PM | $81.25 | $121.84 |
| Previous close 03/12/2026 | $81.68 | $122.62 |
| Consolidated volume 03/12/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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BBP | XBI | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
BBP | XBI | |
|---|---|---|
| Last price | $81.25 | $121.84 |
| 1D performance | -0.53% | -0.64% |
| AuM | $50.55 M | $7.79 B |
| E/R | 0.79% | 0.35% |
BBP | XBI | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | VIRTUS Investment Partners | SPDR |
| Benchmark | LifeSci Biotechnology Products Index | S&P Biotechnology Select Industry Index |
| N° of holdings | 58 | 123 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | January 31, 2006 |
| ESG | No | No |
Countries
Sectors
Diversification
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
Top 15 holdings
How have the BBP and XBI ETFs performed in 2026?
As of March 11, 2026, BBP is up 5.62% year-to-date (YTD), while XBI has returned 0.54%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or XBI?
Year-to-date, the BBP ETF saw +$4M in flows, compared to -$130M for XBI.
Which ETF is more volatile: BBP or XBI?
Over the past year, BBP had a volatility of 25.49%, while XBI experienced 28.2%.
Which ETF is bigger: BBP or XBI?
As of March 11, 2026, BBP holds $50.55 M in assets under management (AUM), while XBI manages $7.79 B.
What sectors do the BBP and XBI ETFs invest in?
BBP leans toward sectors like Health Care. Meanwhile, XBI focuses on Health Care.
What are the top holdings of the BBP ETF and XBI ETF?
BBP top holdings include DAY ONE BIOPHARMACEUTICALS, DYNAVAX TECHNOLOGIES and AMICUS THERAPEUTICS. XBI holds in its top three: MODERNA INC, MIRUM PHARMACEUTICALS INC and REVOLUTION MEDICINES INC.
Which ETF is more diversified: BBP or XBI?
BBP holds 63 securities with 30.11% of its assets in the top 15. XBI has 149 securities and a top 15 weight of 21.6%.
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