BBPvsXBIETF Comparison
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Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. State Street SPDR S&P Biotech ETF (XBI) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. BBP is more expensive with a Total Expense Ratio (TER) of 0.79%, versus 0.35% for XBI. BBP is up 9.25% year-to-date (YTD) with +$30M in YTD flows. XBI performs better with 9.68% YTD performance, and -$269M in YTD flows. Run a side-by-side ETF comparison of BBP and XBI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBP vs XBI performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP XBI | -1.38%-0.89% | +7.00%+9.09% | +9.25%+9.68% | +43.65%+59.15% | +60.05%+51.71% | +58.90%-1.65% |
| Flows | BBP XBI | +$4M-$91M | +$26M-$210M | +$30M-$269M | +$42M+$444M | +$45M-$1.14B | +$38M+$810M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP XBI | +28.75%+32.47% | +24.06%+26.10% | +24.00%+27.60% | +26.36%+32.77% |
| Max drawdown | BBP XBI | -7.49%-8.56% | -9.59%-9.66% | -25.54%-32.94% | -37.87%-54.69% |
| Max drawdown duration | BBP XBI | 37d54d | 48d76d | 292d331d | 760d1754d |
Trading data
BBP | XBI | |
Last sale 6/12/2026 at 1:30 PM | $87.17 | $133.79 |
| Previous close 06/11/2026 | $86.80 | $132.74 |
| Consolidated volume 06/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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BBP | XBI | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/12/2026 at 1:30 PM
Live
Closed
BBP | XBI | |
|---|---|---|
| Last price | $87.17 | $133.79 |
| 1D performance | +0.42% | +0.79% |
| AuM | $78.43 M | $8.30 B |
| E/R | 0.79% | 0.35% |
Characteristics
BBP | XBI | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | VIRTUS Investment Partners | State Street Investment Management |
| Benchmark | LifeSci Biotechnology Products Index | S&P Biotechnology Select Industry Index |
| N° of holdings | 55 | 119 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | January 31, 2006 |
| ESG | No | No |
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Exposure
Countries
BBP
USA
84.13%
Other
15.87%
XBI
USA
94.81%
Other
5.19%
Sectors
BBP
Health Care
85.97%
Other
14.03%
XBI
Health Care
85.15%
Other
14.85%
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Diversification
BBP
Total weight of top 15 holdings out of 15
45.32%
XBI
Total weight of top 15 holdings out of 15
20.97%
Top 15 holdings
Data as of April 30, 2026
BBP
ARROWHEAD PHARMACEUTICALS INC
3.17%
GB00BRXB0C07
3.17%
BIOGEN INC
3.14%
HALOZYME THERAPEUTICS
3.13%
AURINIA PHARMACEUTICALS INC
3.12%
SYNDAX PHARMACEUTICALS INC
3.12%
BIOMARIN PHARMACEUTICAL
3.05%
INCYTE
3.03%
REGENERON PHARMACEUTICALS
3.03%
BRIDGEBIO PHARMA
3.00%
SAREPTA THERAPEUTICS INC DE
2.95%
ARDELYX
2.92%
VERTEX PHARMACEUTICALS
2.85%
US07725L1026
2.83%
THERAVANCE BIOPHARMA
2.80%
XBI
APELLIS PHARMACEUTICALS
1.87%
REVOLUTION MEDICINES INC
1.65%
TRAVERE THERAPEUTICS INC
1.62%
ARROWHEAD PHARMACEUTICALS INC
1.44%
TWIST BIOSCIENCE CORP
1.42%
US86627T1088
1.40%
ALKERMES
1.38%
TG THERAPEUTICS
1.37%
MADRIGAL PHARMACEUTICALS INC
1.36%
BEAM THERAPEUTICS
1.32%
US03770N1019
1.26%
SCHOLAR ROCK HOLDING CORP
1.23%
US74006W2070
1.22%
EXELIXIS
1.21%
MIRUM PHARMACEUTICALS INC
1.21%
Frequently asked questions about BBP and XBI
How have the BBP and XBI ETFs performed in 2026?
As of June 12, 2026, BBP is up 9.25% year-to-date (YTD), while XBI has returned 9.68%. That puts XBI better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or XBI?
Year-to-date, the BBP ETF saw +$30M in flows, compared to -$269M for XBI.
Which ETF is more volatile: BBP or XBI?
Over the past year, BBP had a volatility of 24.06%, while XBI experienced 26.1%.
Which ETF is bigger: BBP or XBI?
As of June 12, 2026, BBP holds $78.43 M in assets under management (AUM), while XBI manages $8.30 B.
What sectors do the BBP and XBI ETFs invest in?
BBP leans toward sectors like Health Care. Meanwhile, XBI focuses on Health Care.
What are the top holdings of the BBP ETF and XBI ETF?
BBP top holdings include ARROWHEAD PHARMACEUTICALS INC, GB00BRXB0C07 and BIOGEN INC. XBI holds in its top three: APELLIS PHARMACEUTICALS, REVOLUTION MEDICINES INC and TRAVERE THERAPEUTICS INC.
Which ETF is more diversified: BBP or XBI?
BBP holds 59 securities with 45.32% of its assets in the top 15. XBI has 148 securities and a top 15 weight of 20.97%.
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