ARKGvsXBIETF Comparison
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ARK Genomic Revolution ETF (ARKG) belongs to the BioTech & Genomics segment. State Street SPDR S&P Biotech ETF (XBI) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Healthcare. ARKG is more expensive with a Total Expense Ratio (TER) of 0.75%, versus 0.35% for XBI. ARKG is up 29.47% year-to-date (YTD) with +$39M in YTD flows. XBI performs worse with 23.56% YTD performance, and +$394M in YTD flows. Run a side-by-side ETF comparison of ARKG and XBI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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ARKG vs XBI performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | ARKG XBI | -1.87%+0.59% | +27.92%+13.07% | +29.47%+23.56% | +45.31%+72.81% | +4.16%+81.55% | -54.66%+21.91% |
| Flows | ARKG XBI | +$81M-$259M | +$62M+$434M | +$39M+$394M | -$3M+$1.35B | -$550M-$541M | -$2.57B+$1.29B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | ARKG XBI | +44.86%+30.66% | +42.64%+26.75% | +43.40%+27.88% | +45.98%+32.89% |
| Max drawdown | ARKG XBI | -13.14%-8.33% | -27.52%-9.66% | -51.67%-32.94% | -79.29%-54.07% |
| Max drawdown duration | ARKG XBI | 18d15d | 126d76d | 1058d331d | 1814d1685d |
Trading data
ARKG | XBI | |
Last sale 7/27/2026 at 1:30 PM | $37.75 | $150.62 |
| Previous close 07/24/2026 | $37.81 | $150.48 |
| Consolidated volume 07/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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ARKG
is actively managed and doesn’t replicate an indexARKG | XBI | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
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Main metrics
Last update 7/27/2026 at 1:30 PM
Live
Closed
ARKG | XBI | |
|---|---|---|
| Last price | $37.75 | $150.62 |
| 1D performance | -0.16% | +0.09% |
| AuM | $1.53 B | $10.02 B |
| E/R | 0.75% | 0.35% |
Characteristics
ARKG | XBI | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Ark Investment | State Street Investment Management |
| Benchmark | - | S&P Biotechnology Select Industry Index |
| N° of holdings | 31 | 150 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | April 2, 2019 | January 31, 2006 |
| ESG | No | No |
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Exposure
Countries
ARKG
USA
86.99%
Other
13.01%
XBI
USA
95.06%
Other
4.94%
Sectors
ARKG
Healthcare
96.93%
Other
3.07%
XBI
Healthcare
99.03%
Other
0.97%
Diversification
ARKG
Total weight of top 15 holdings out of 15
74.95%
XBI
Total weight of top 15 holdings out of 15
19.19%
Top 15 holdings
Data as of June 30, 2026
ARKG
Twist Bioscience Corp.
9.15%
Tempus AI, Inc.
7.64%
Absci Corp.
7.01%
10X Genomics, Inc.
7.00%
CRISPR Therapeutics AG
6.56%
Personalis, Inc.
6.19%
Beam Therapeutics, Inc.
4.34%
Guardant Health, Inc.
4.28%
Natera, Inc.
4.11%
Illumina, Inc.
3.98%
Veracyte, Inc.
3.24%
CareDx, Inc.
3.08%
Recursion Pharmaceuticals, Inc.
2.85%
Eli Lilly & Co.
2.81%
Compass Pathways Plc
2.70%
XBI
Apogee Therapeutics, Inc.
1.48%
Moderna, Inc.
1.41%
Twist Bioscience Corp.
1.40%
Oruka Therapeutics, Inc.
1.37%
Kymera Therapeutics, Inc.
1.35%
Viking Therapeutics, Inc.
1.30%
Praxis Precision Medicines, Inc.
1.29%
Erasca, Inc.
1.27%
Revolution Medicines, Inc.
1.20%
Rhythm Pharmaceuticals, Inc.
1.20%
CG Oncology, Inc.
1.20%
SELLAS Life Sciences Group, Inc.
1.19%
Vaxcyte, Inc.
1.18%
Dianthus Therapeutics, Inc.
1.18%
Cytokinetics, Inc.
1.17%
Frequently asked questions about ARKG and XBI
How have the ARKG and XBI ETFs performed in 2026?
As of July 24, 2026, ARKG is up 29.47% year-to-date (YTD), while XBI has returned 23.56%. That puts ARKG better performer ahead so far this year.
Which ETF is attracting more investor money: ARKG or XBI?
Year-to-date, the ARKG ETF saw +$39M in flows, compared to +$394M for XBI.
Which ETF is more volatile: ARKG or XBI?
Over the past year, ARKG had a volatility of 42.64%, while XBI experienced 26.75%.
Which ETF is bigger: ARKG or XBI?
As of July 24, 2026, ARKG holds $1.53 B in assets under management (AUM), while XBI manages $10.02 B.
What sectors do the ARKG and XBI ETFs invest in?
ARKG leans toward sectors like Healthcare. Meanwhile, XBI focuses on Healthcare.
What are the top holdings of the ARKG ETF and XBI ETF?
ARKG top holdings include Twist Bioscience Corp., Tempus AI, Inc. and Absci Corp.. XBI holds in its top three: Apogee Therapeutics, Inc., Moderna, Inc. and Twist Bioscience Corp..
Which ETF is more diversified: ARKG or XBI?
ARKG holds 31 securities with 74.95% of its assets in the top 15. XBI has 153 securities and a top 15 weight of 19.19%.
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ARKG
XBI
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