XPHvsVHTETF Comparison
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State Street SPDR S&P Pharmaceuticals ETF (XPH) and Vanguard Health Care ETF (VHT) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. XPH is more expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.09% for VHT. XPH is up 7.68% year-to-date (YTD) with +$110M in YTD flows. VHT performs worse with -0.09% YTD performance, and -$247M in YTD flows. Run a side-by-side ETF comparison of XPH and VHT below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XPH vs VHT performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XPH VHT | +3.73%+5.01% | +12.67%+3.70% | +7.68%-0.09% | +44.62%+15.85% | +53.31%+23.91% | +21.61%+26.17% |
| Flows | XPH VHT | -$8M+$38M | +$23M-$96M | +$110M-$247M | +$133M-$686M | +$51M-$2.57B | +$63M-$408M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XPH VHT | +25.05%+16.17% | +21.48%+14.77% | +19.89%+14.00% | +20.72%+15.20% |
| Max drawdown | XPH VHT | -8.13%-4.53% | -11.78%-10.39% | -23.45%-16.88% | -31.59%-17.77% |
| Max drawdown duration | XPH VHT | 37d22d | 50d156d | 322d435d | 1566d767d |
Trading data
XPH | VHT | |
Last sale 6/12/2026 at 1:30 PM | $60.27 | $286.46 |
| Previous close 06/11/2026 | $59.77 | $286.80 |
| Consolidated volume 06/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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XPH | VHT | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/12/2026 at 1:30 PM
Live
Closed
XPH | VHT | |
|---|---|---|
| Last price | $60.27 | $286.46 |
| 1D performance | +0.84% | -0.12% |
| AuM | $364.98 M | $17.00 B |
| E/R | 0.35% | 0.09% |
Characteristics
XPH | VHT | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | State Street Investment Management | Vanguard |
| Benchmark | S&P Pharmaceuticals Select Industry Index | MSCI US IMI Health Care 25/50 Index |
| N° of holdings | 48 | 343 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 19, 2006 | January 26, 2004 |
| ESG | No | No |
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Exposure
Countries
XPH
USA
89.49%
Other
10.51%
VHT
USA
96.73%
Other
3.27%
Sectors
XPH
Health Care
82.05%
Other
17.95%
VHT
Health Care
96.88%
Other
3.12%
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Diversification
XPH
Total weight of top 15 holdings out of 15
33.31%
VHT
Total weight of top 15 holdings out of 15
60.28%
Top 15 holdings
Data as of April 30, 2026
XPH
ORGANON & CO
3.72%
CORCEPT THERAPEUTICS
2.48%
US29337E1029
2.41%
AXSOME THERA CMN STK
2.34%
OMEROS
2.20%
PERRIGO CO PLC
2.17%
US6402683063
2.08%
TREVI THERAPEUTICS
2.07%
TERNS PHARMACEUTICALS
2.03%
US45579U1097
2.01%
PACIRA BIOSCIENCES INC
2.00%
HARROW HEALTH
1.97%
JAZZ PHARMACEUTICALS
1.97%
HARMONY BIOSCIENCES HLDG
1.95%
ROYALTY PHARMA
1.93%
VHT
LILLY
12.13%
JOHNSON&JOHNSON
8.82%
ABBVIE
6.03%
UNITEDHEALTH GRP
5.42%
MERCK & CO INC
4.38%
AMGEN-T
3.01%
THERMO FISHER SCIENTIFIC
2.91%
GILEAD SCIENCES
2.62%
INTUITIVE SURGICAL
2.62%
ABBOTT LABS
2.55%
PFIZER
2.45%
BRISTOL-MYERS SQUIBB
1.99%
DANAHER
1.84%
STRYKER
1.75%
VERTEX PHARMACEUTICALS
1.75%
Frequently asked questions about XPH and VHT
How have the XPH and VHT ETFs performed in 2026?
As of June 12, 2026, XPH is up 7.68% year-to-date (YTD), while VHT has lost -0.09%. That puts XPH better performer ahead so far this year.
Which ETF is attracting more investor money: XPH or VHT?
Year-to-date, the XPH ETF saw +$110M in flows, compared to -$247M for VHT.
Which ETF is more volatile: XPH or VHT?
Over the past year, XPH had a volatility of 21.48%, while VHT experienced 14.77%.
Which ETF is bigger: XPH or VHT?
As of June 12, 2026, XPH holds $364.98 M in assets under management (AUM), while VHT manages $17.00 B.
What sectors do the XPH and VHT ETFs invest in?
XPH leans toward sectors like Health Care. Meanwhile, VHT focuses on Health Care.
What are the top holdings of the XPH ETF and VHT ETF?
XPH top holdings include ORGANON & CO, CORCEPT THERAPEUTICS and US29337E1029. VHT holds in its top three: LILLY, JOHNSON&JOHNSON and ABBVIE.
Which ETF is more diversified: XPH or VHT?
XPH holds 58 securities with 33.31% of its assets in the top 15. VHT has 401 securities and a top 15 weight of 60.28%.
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Latest news about XPH & VHT
My Contrarian Equity ETF Picks For 2026
November 13, 2025
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Donald Trump’s Executive Orders: ETF Bulls and Bears
January 24, 2025
XPH
Healthcare Stocks Drop on Medicare Payment Rate Surprise
April 8, 2024
VHT
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Health Care Sector Down After a Cyberattack on UnitedHealth
March 4, 2024
VHT
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