WDNAvsIBBETF Comparison
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WisdomTree BioRevolution Fund (WDNA) belongs to the BioTech & Genomics segment. iShares Biotechnology ETF (IBB) is part of the US Health Care segment. WDNA's top 3 sector exposures are Healthcare, Non-Energy Materials and Consumer Non-Cyclicals. In contrast, IBB's top sector exposures are Healthcare, Non-Corporate and Non-Energy Materials. WDNA is more expensive with a Total Expense Ratio (TER) of 0.45%, versus 0.44% for IBB. WDNA is up 37.08% year-to-date (YTD) with +$1M in YTD flows. IBB performs worse with 22.86% YTD performance, and +$423M in YTD flows. Run a side-by-side ETF comparison of WDNA and IBB below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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WDNA vs IBB performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/17/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | WDNA IBB | +8.32%+2.65% | +23.93%+19.42% | +37.08%+22.86% | +65.32%+47.21% | +56.19%+66.86% | -8.47%+20.98% |
| Flows | WDNA IBB | +$2M+$249M | +$2M+$748M | +$1M+$423M | +$1M+$1.82B | +$1M-$523M | +$3M-$1.15B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | WDNA IBB | +34.69%+24.44% | +28.13%+21.82% | +26.37%+21.11% | +25.79%+22.49% |
| Max drawdown | WDNA IBB | -9.35%-6.84% | -11.90%-9.61% | -36.45%-24.82% | -57.38%-38.96% |
| Max drawdown duration | WDNA IBB | 42d29d | 147d151d | 595d377d | 1820d1523d |
Trading data
WDNA | IBB | |
Last sale 9/17/2026 at 7:55 PM | $23.29 | $205.09 |
| Previous close 09/17/2026 | $22.27 | $207.07 |
| Consolidated volume 09/17/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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WDNA | IBB | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/17/2026 at 7:55 PM
Live
Closed
WDNA | IBB | |
|---|---|---|
| Last price | $23.29 | $205.09 |
| 1D performance | +4.59% | -0.96% |
| AuM | $4.64 M | $10.62 B |
| E/R | 0.45% | 0.44% |
Characteristics
WDNA | IBB | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | WisdomTree | iShares |
| Benchmark | WisdomTree BioRevolution Index | ICE Biotechnology Index |
| N° of holdings | 79 | 240 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 3, 2021 | February 5, 2001 |
| ESG | No | No |
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Exposure
Countries
WDNA
USA
83.75%
Other
16.25%
IBB
USA
86.04%
Other
13.96%
Sectors
WDNA
Healthcare
88.38%
Non-Energy Materi.
7.38%
Other
4.25%
IBB
Healthcare
99.83%
Other
0.17%
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Diversification
WDNA
Total weight of top 15 holdings out of 15
40.46%
IBB
Total weight of top 15 holdings out of 15
54.48%
Top 15 holdings
Data as of July 31, 2026
WDNA
Twist Bioscience Corp.
5.53%
Eli Lilly & Co.
4.11%
Moderna, Inc.
3.59%
Johnson & Johnson
3.13%
Immunome, Inc.
2.57%
United Therapeutics Corp.
2.50%
10X Genomics, Inc.
2.44%
Natera, Inc.
2.42%
Darling Ingredients, Inc.
2.26%
Corteva, Inc.
2.19%
Structure Therapeutics, Inc.
2.04%
Stoke Therapeutics, Inc.
2.02%
Krystal Biotech, Inc.
2.01%
Thermo Fisher Scientific, Inc.
1.83%
Tempus AI, Inc.
1.82%
IBB
Amgen, Inc.
8.42%
Vertex Pharmaceuticals, Inc.
7.87%
Gilead Sciences, Inc.
7.14%
Regeneron Pharmaceuticals, Inc.
5.84%
argenx SE
3.55%
Natera, Inc.
2.88%
Revolution Medicines, Inc.
2.87%
Illumina, Inc.
2.42%
Biogen, Inc.
2.38%
Alnylam Pharmaceuticals, Inc.
2.14%
BeOne Medicines Ltd.
2.01%
Incyte Corp.
1.91%
Insmed, Inc.
1.71%
United Therapeutics Corp.
1.69%
Moderna, Inc.
1.65%
Frequently asked questions about WDNA and IBB
How have the WDNA and IBB ETFs performed in 2026?
As of September 17, 2026, WDNA is up 37.08% year-to-date (YTD), while IBB has returned 22.86%. That puts WDNA better performer ahead so far this year.
Which ETF is attracting more investor money: WDNA or IBB?
Year-to-date, the WDNA ETF saw +$1M in flows, compared to +$423M for IBB.
Which ETF is more volatile: WDNA or IBB?
Over the past year, WDNA had a volatility of 28.13%, while IBB experienced 21.82%.
Which ETF is bigger: WDNA or IBB?
As of September 17, 2026, WDNA holds $4.64 M in assets under management (AUM), while IBB manages $10.62 B.
What sectors do the WDNA and IBB ETFs invest in?
WDNA leans toward sectors like Healthcare and Non-Energy Materials. Meanwhile, IBB focuses on Healthcare.
What are the top holdings of the WDNA ETF and IBB ETF?
WDNA top holdings include Twist Bioscience Corp., Eli Lilly & Co. and Moderna, Inc.. IBB holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..
Which ETF is more diversified: WDNA or IBB?
WDNA holds 79 securities with 40.46% of its assets in the top 15. IBB has 241 securities and a top 15 weight of 54.48%.
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