TMEDvsIBBETF Comparison
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T. Rowe Price Health Care ETF (TMED) and iShares Biotechnology ETF (IBB) belong to the same industry segment: US Health Care. TMED's top 3 sector exposures are Healthcare, Consumer Non-Cyclicals and Non-Corporate. In contrast, IBB's top sector exposures are Healthcare, Non-Corporate and Non-Energy Materials. Both TMED and IBB have the same Total Expense Ratio (TER) of 0.44%. TMED is up 16.23% year-to-date (YTD) with +$15M in YTD flows. IBB performs better with 23.18% YTD performance, and +$518M in YTD flows. Run a side-by-side ETF comparison of TMED and IBB below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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TMED vs IBB performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/22/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | TMED IBB | -0.47%+0.43% | +2.02%+9.91% | +16.23%+23.18% | +21.78%+34.66% | n/a+80.34% | n/a+31.28% |
| Flows | TMED IBB | +$2M+$199M | +$10M+$401M | +$15M+$518M | +$16M+$1.79B | --$103M | --$1.01B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | TMED IBB | +19.33%+25.99% | +18.68%+22.63% | n/a+21.42% | n/a+22.58% |
| Max drawdown | TMED IBB | -10.10%-7.78% | -11.09%-9.61% | n/a-24.82% | n/a-35.62% |
| Max drawdown duration | TMED IBB | 64d65d | 125d151d | n/a377d | n/a1468d |
Trading data
TMED | IBB | |
Last sale 10/23/2026 at 1:30 PM | $34.08 | $207.74 |
| Previous close 10/22/2026 | $34.49 | $209.54 |
| Consolidated volume 10/22/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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TMED
is actively managed and doesn’t replicate an indexTMED | IBB | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 10/23/2026 at 1:30 PM
Live
Closed
TMED | IBB | |
|---|---|---|
| Last price | $34.08 | $207.74 |
| 1D performance | -1.20% | -0.86% |
| AuM | $34.50 M | $10.73 B |
| E/R | 0.44% | 0.44% |
Characteristics
TMED | IBB | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | T. Rowe Price | iShares |
| Benchmark | - | NYSE Biotechnology Index |
| N° of holdings | 106 | 241 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 11, 2025 | February 5, 2001 |
| ESG | No | No |
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Exposure
Countries
TMED
USA
92.86%
Other
7.14%
IBB
USA
86.02%
Other
13.98%
Sectors
TMED
Healthcare
98.26%
Other
1.74%
IBB
Healthcare
99.9%
Other
0.1%
Diversification
TMED
Total weight of top 15 holdings out of 15
56.93%
IBB
Total weight of top 15 holdings out of 15
56.64%
Top 15 holdings
Data as of August 31, 2026
TMED
Eli Lilly & Co.
13.87%
UnitedHealth Group, Inc.
5.32%
Alnylam Pharmaceuticals, Inc.
5.20%
Thermo Fisher Scientific, Inc.
3.74%
Cencora, Inc.
3.65%
Insulet Corp.
3.23%
Gilead Sciences, Inc.
2.99%
Agilent Technologies, Inc.
2.85%
Elanco Animal Health, Inc.
2.63%
Dyne Therapeutics, Inc.
2.47%
Boston Scientific Corp.
2.25%
Stryker Corp.
2.21%
Danaher Corp.
2.20%
Waters Corp.
2.17%
West Pharmaceutical Services, Inc.
2.16%
IBB
Amgen, Inc.
8.45%
Vertex Pharmaceuticals, Inc.
8.05%
Gilead Sciences, Inc.
7.21%
Regeneron Pharmaceuticals, Inc.
5.72%
argenx SE
3.80%
Moderna, Inc.
3.62%
Natera, Inc.
3.12%
Revolution Medicines, Inc.
2.78%
Illumina, Inc.
2.29%
Alnylam Pharmaceuticals, Inc.
2.27%
Biogen, Inc.
2.25%
BeOne Medicines Ltd.
2.03%
Insmed, Inc.
1.85%
Incyte Corp.
1.73%
United Therapeutics Corp.
1.49%
Frequently asked questions about TMED and IBB
How have the TMED and IBB ETFs performed in 2026?
As of October 22, 2026, TMED is up 16.23% year-to-date (YTD), while IBB has returned 23.18%. That puts IBB better performer ahead so far this year.
Which ETF is attracting more investor money: TMED or IBB?
Year-to-date, the TMED ETF saw +$15M in flows, compared to +$518M for IBB.
Which ETF is more volatile: TMED or IBB?
Over the past year, TMED had a volatility of 18.68%, while IBB experienced 22.63%.
Which ETF is bigger: TMED or IBB?
As of October 22, 2026, TMED holds $34.50 M in assets under management (AUM), while IBB manages $10.73 B.
What sectors do the TMED and IBB ETFs invest in?
TMED leans toward sectors like Healthcare. Meanwhile, IBB focuses on Healthcare.
What are the top holdings of the TMED ETF and IBB ETF?
TMED top holdings include Eli Lilly & Co., UnitedHealth Group, Inc. and Alnylam Pharmaceuticals, Inc.. IBB holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..
Which ETF is more diversified: TMED or IBB?
TMED holds 106 securities with 56.93% of its assets in the top 15. IBB has 241 securities and a top 15 weight of 56.64%.
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