MDEVvsIBBETF Comparison
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First Trust Indxx Medical Devices ETF (MDEV) belongs to the Healthcare Technology segment. iShares Biotechnology ETF (IBB) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Healthcare. MDEV is more expensive with a Total Expense Ratio (TER) of 0.7%, versus 0.44% for IBB. MDEV is down -3.05% year-to-date (YTD) with +$994K in YTD flows. IBB performs better with 12.65% YTD performance, and +$41M in YTD flows. Run a side-by-side ETF comparison of MDEV and IBB below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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MDEV vs IBB performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/30/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | MDEV IBB | +6.20%-0.07% | +9.77%+12.62% | -3.05%+12.65% | -0.45%+42.44% | -2.20%+48.25% | -23.17%+16.09% |
| Flows | MDEV IBB | +$994K+$314M | +$994K+$368M | +$994K+$41M | +$994K+$1.40B | +$767K-$923M | -$23M-$1.93B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | MDEV IBB | +17.24%+22.20% | +16.50%+20.34% | +16.33%+20.41% | +19.16%+22.30% |
| Max drawdown | MDEV IBB | -3.88%-5.94% | -18.07%-9.61% | -21.75%-24.82% | -42.16%-39.75% |
| Max drawdown duration | MDEV IBB | 11d23d | 205d151d | 205d377d | 1787d1611d |
Trading data
MDEV | IBB | |
Last sale 7/30/2026 at 1:30 PM | $20.16 | $189.96 |
| Previous close 07/30/2026 | $20.27 | $188.53 |
| Consolidated volume 07/30/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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MDEV | IBB | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/30/2026 at 1:30 PM
Live
Closed
MDEV | IBB | |
|---|---|---|
| Last price | $20.16 | $189.96 |
| 1D performance | -0.55% | +0.76% |
| AuM | $3.06 M | $9.39 B |
| E/R | 0.7% | 0.44% |
Characteristics
MDEV | IBB | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | iShares |
| Benchmark | Indxx Global Medical Equipment Index | ICE Biotechnology Index |
| N° of holdings | 47 | 242 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 23, 2021 | February 5, 2001 |
| ESG | No | No |
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Exposure
Countries
MDEV
USA
55.63%
Japan
7.86%
Other
36.51%
IBB
USA
86.15%
Other
13.85%
Sectors
MDEV
Healthcare
95.26%
Other
4.74%
IBB
Healthcare
99.89%
Other
0.11%
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Diversification
MDEV
Total weight of top 15 holdings out of 15
35.95%
IBB
Total weight of top 15 holdings out of 15
53.71%
Top 15 holdings
Data as of June 30, 2026
MDEV
West Pharmaceutical Services, Inc.
2.88%
Demant A/S
2.76%
LivaNova Plc
2.67%
Baxter International, Inc.
2.57%
Revvity, Inc.
2.55%
WuXi AppTec Co., Ltd.
2.41%
Waters Corp.
2.40%
Edwards Lifesciences Corp.
2.40%
Agilent Technologies, Inc.
2.36%
Teleflex, Inc.
2.23%
DexCom, Inc.
2.18%
Bio-Rad Laboratories, Inc.
2.16%
Sonova Holding AG
2.13%
Align Technology, Inc.
2.13%
Sysmex Corp.
2.12%
IBB
Vertex Pharmaceuticals, Inc.
8.07%
Amgen, Inc.
7.82%
Gilead Sciences, Inc.
6.83%
Regeneron Pharmaceuticals, Inc.
4.90%
argenx SE
3.75%
Alnylam Pharmaceuticals, Inc.
3.12%
Natera, Inc.
2.89%
Revolution Medicines, Inc.
2.78%
Biogen, Inc.
2.46%
Illumina, Inc.
2.07%
Moderna, Inc.
1.98%
Insmed, Inc.
1.78%
BeOne Medicines Ltd.
1.77%
Incyte Corp.
1.75%
United Therapeutics Corp.
1.73%
Frequently asked questions about MDEV and IBB
How have the MDEV and IBB ETFs performed in 2026?
As of July 30, 2026, MDEV is down -3.05% year-to-date (YTD), while IBB has returned 12.65%. That puts IBB better performer ahead so far this year.
Which ETF is attracting more investor money: MDEV or IBB?
Year-to-date, the MDEV ETF saw +$994K in flows, compared to +$41M for IBB.
Which ETF is more volatile: MDEV or IBB?
Over the past year, MDEV had a volatility of 16.5%, while IBB experienced 20.34%.
Which ETF is bigger: MDEV or IBB?
As of July 30, 2026, MDEV holds $3.06 M in assets under management (AUM), while IBB manages $9.39 B.
What sectors do the MDEV and IBB ETFs invest in?
MDEV leans toward sectors like Healthcare. Meanwhile, IBB focuses on Healthcare.
What are the top holdings of the MDEV ETF and IBB ETF?
MDEV top holdings include West Pharmaceutical Services, Inc., Demant A/S and LivaNova Plc. IBB holds in its top three: Vertex Pharmaceuticals, Inc., Amgen, Inc. and Gilead Sciences, Inc..
Which ETF is more diversified: MDEV or IBB?
MDEV holds 47 securities with 35.95% of its assets in the top 15. IBB has 242 securities and a top 15 weight of 53.71%.
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