MDEVvsIBBETF Comparison
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First Trust Indxx Medical Devices ETF (MDEV) belongs to the Healthcare Technology segment. iShares Biotechnology ETF (IBB) is part of the US Health Care segment. MDEV's top 1 sector exposures are Healthcare. In contrast, IBB's top sector exposures are Healthcare, Non-Corporate and Non-Energy Materials. MDEV is more expensive with a Total Expense Ratio (TER) of 0.7%, versus 0.44% for IBB. MDEV is down -1.75% year-to-date (YTD) with +$994K in YTD flows. IBB performs better with 22.86% YTD performance, and +$423M in YTD flows. Run a side-by-side ETF comparison of MDEV and IBB below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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MDEV vs IBB performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/16/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | MDEV IBB | -2.73%+2.65% | +9.99%+19.42% | -1.75%+22.86% | +1.51%+47.21% | +10.26%+66.86% | -25.10%+20.98% |
| Flows | MDEV IBB | -+$249M | +$994K+$748M | +$994K+$423M | +$994K+$1.82B | +$767K-$523M | -$24M-$1.15B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | MDEV IBB | +17.31%+24.44% | +16.32%+21.82% | +16.40%+21.11% | +19.25%+22.49% |
| Max drawdown | MDEV IBB | -6.88%-6.84% | -18.07%-9.61% | -20.26%-24.82% | -41.66%-38.96% |
| Max drawdown duration | MDEV IBB | 24d29d | 253d151d | 594d377d | 1819d1523d |
Trading data
MDEV | IBB | |
Last sale 9/17/2026 at 1:30 PM | $20.47 | $207.07 |
| Previous close 09/17/2026 | $20.44 | $202.40 |
| Consolidated volume 09/17/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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MDEV | IBB | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/17/2026 at 1:30 PM
Live
Closed
MDEV | IBB | |
|---|---|---|
| Last price | $20.47 | $207.07 |
| 1D performance | +0.16% | +2.31% |
| AuM | $3.10 M | $10.62 B |
| E/R | 0.7% | 0.44% |
Characteristics
MDEV | IBB | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | iShares |
| Benchmark | Indxx Global Medical Equipment Index | ICE Biotechnology Index |
| N° of holdings | 47 | 240 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 23, 2021 | February 5, 2001 |
| ESG | No | No |
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Exposure
Countries
MDEV
USA
55.07%
Japan
8.74%
Other
36.19%
IBB
USA
86.04%
Other
13.96%
Sectors
MDEV
Healthcare
95.98%
Other
4.02%
IBB
Healthcare
99.83%
Other
0.17%
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Diversification
MDEV
Total weight of top 15 holdings out of 15
37.67%
IBB
Total weight of top 15 holdings out of 15
54.48%
Top 15 holdings
Data as of July 31, 2026
MDEV
WuXi AppTec Co., Ltd.
2.91%
Baxter International, Inc.
2.82%
Demant A/S
2.62%
DexCom, Inc.
2.57%
Olympus Corp.
2.55%
Sysmex Corp.
2.54%
Revvity, Inc.
2.53%
West Pharmaceutical Services, Inc.
2.51%
Agilent Technologies, Inc.
2.48%
Bio-Rad Laboratories, Inc.
2.46%
Merit Medical Systems, Inc.
2.42%
Sonova Holding AG
2.38%
Waters Corp.
2.31%
Thermo Fisher Scientific, Inc.
2.29%
LivaNova Plc
2.28%
IBB
Amgen, Inc.
8.42%
Vertex Pharmaceuticals, Inc.
7.87%
Gilead Sciences, Inc.
7.14%
Regeneron Pharmaceuticals, Inc.
5.84%
argenx SE
3.55%
Natera, Inc.
2.88%
Revolution Medicines, Inc.
2.87%
Illumina, Inc.
2.42%
Biogen, Inc.
2.38%
Alnylam Pharmaceuticals, Inc.
2.14%
BeOne Medicines Ltd.
2.01%
Incyte Corp.
1.91%
Insmed, Inc.
1.71%
United Therapeutics Corp.
1.69%
Moderna, Inc.
1.65%
Frequently asked questions about MDEV and IBB
How have the MDEV and IBB ETFs performed in 2026?
As of September 16, 2026, MDEV is down -1.75% year-to-date (YTD), while IBB has returned 22.86%. That puts IBB better performer ahead so far this year.
Which ETF is attracting more investor money: MDEV or IBB?
Year-to-date, the MDEV ETF saw +$994K in flows, compared to +$423M for IBB.
Which ETF is more volatile: MDEV or IBB?
Over the past year, MDEV had a volatility of 16.32%, while IBB experienced 21.82%.
Which ETF is bigger: MDEV or IBB?
As of September 16, 2026, MDEV holds $3.10 M in assets under management (AUM), while IBB manages $10.62 B.
What sectors do the MDEV and IBB ETFs invest in?
MDEV leans toward sectors like Healthcare. Meanwhile, IBB focuses on Healthcare.
What are the top holdings of the MDEV ETF and IBB ETF?
MDEV top holdings include WuXi AppTec Co., Ltd., Baxter International, Inc. and Demant A/S. IBB holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..
Which ETF is more diversified: MDEV or IBB?
MDEV holds 47 securities with 37.67% of its assets in the top 15. IBB has 241 securities and a top 15 weight of 54.48%.
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