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IDNAvsIBBETF Comparison

ETF 1

IDNA

iShares Genomics Immunology and Healthcare ETF

This fund is part of

BioTech & Genomics

-2.11%

Full IDNA fund page

VS

ETF 2

IBB

iShares Biotechnology ETF

This fund is part of

US Health Care

+0.32%

Full IBB fund page

iShares Genomics Immunology and Healthcare ETF (IDNA) belongs to the BioTech & Genomics segment. iShares Biotechnology ETF (IBB) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: Healthcare and Non-Corporate. IDNA is more expensive with a Total Expense Ratio (TER) of 0.47%, versus 0.44% for IBB. IDNA is up 22.74% year-to-date (YTD) with +$29M in YTD flows. IBB performs worse with 11.58% YTD performance, and +$89M in YTD flows. Run a side-by-side ETF comparison of IDNA and IBB below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IDNA vs IBB performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 07/24/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	IDNA IBB	+1.04%+3.70%	+7.23%+10.81%	+22.74%+11.58%	+45.35%+39.33%	+40.59%+46.64%	-31.37%+16.63%
Flows	IDNA IBB	+$13M+$526M	+$16M+$314M	+$29M+$89M	+$25M+$1.44B	+$4M-$939M	+$10M-$1.82B

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	IDNA IBB	+25.18%+22.62%	+23.90%+20.32%	+24.18%+20.40%	+28.01%+22.33%
Max drawdown	IDNA IBB	-8.02%-5.94%	-10.60%-9.61%	-29.33%-24.82%	-68.19%-39.75%
Max drawdown duration	IDNA IBB	19d17d	46d151d	347d377d	1769d1611d

Trading data

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	IDNA	IBB
Last sale 7/27/2026 at 1:30 PM	$32.24	$188.33
Previous close 07/24/2026	$32.03	$188.14
Consolidated volume 07/24/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of June 30, 2026

1-year trailing difference

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	IDNA	IBB
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 7/27/2026 at 1:30 PM

Live

Closed

	IDNA	IBB
Last price	$32.24	$188.33
1D performance	+0.66%	+0.10%
AuM	$188.81 M	$9.34 B
E/R	0.47%	0.44%

Characteristics

	IDNA	IBB
Management strategy	Passive	Passive
Provider	iShares	iShares
Benchmark	NYSE FactSet Global Genomics and Immuno Biopharma Index	ICE Biotechnology Index
N° of holdings	48	242
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 11, 2019	February 5, 2001
ESG	No	No

More IDNA data on Trackinsight

More IBB data on Trackinsight

Exposure

Countries

IDNA

USA

61.08%

Germany

8.29%

France

7.46%

Other

23.17%

IBB

USA

86.15%

Other

13.85%

Sectors

IDNA

Healthcare

99.73%

Other

0.27%

IBB

Healthcare

99.89%

Other

0.11%

Diversification

IDNA

Total weight of top 15 holdings out of 15

59.79%

IBB

Total weight of top 15 holdings out of 15

53.71%

Top 15 holdings

Data as of June 30, 2026

IDNA

Twist Bioscience Corp.

5.18%

Moderna, Inc.

5.14%

Bayer AG

4.61%

Revolution Medicines, Inc.

4.37%

Genmab A/S

3.88%

Vertex Pharmaceuticals, Inc.

3.87%

Incyte Corp.

3.86%

Merck & Co., Inc.

3.71%

Ipsen SA

3.69%

BioNTech SE

3.68%

ImmunityBio, Inc.

3.60%

Exelixis, Inc.

3.60%

Takeda Pharmaceutical Co., Ltd.

3.59%

GSK Plc

3.53%

Roche Holding AG

3.49%

IBB

Vertex Pharmaceuticals, Inc.

8.07%

Amgen, Inc.

7.82%

Gilead Sciences, Inc.

6.83%

Regeneron Pharmaceuticals, Inc.

4.90%

argenx SE

3.75%

Alnylam Pharmaceuticals, Inc.

3.12%

Natera, Inc.

2.89%

Revolution Medicines, Inc.

2.78%

Biogen, Inc.

2.46%

Illumina, Inc.

2.07%

Moderna, Inc.

1.98%

Insmed, Inc.

1.78%

BeOne Medicines Ltd.

1.77%

Incyte Corp.

1.75%

United Therapeutics Corp.

1.73%

Frequently asked questions about IDNA and IBB

How have the IDNA and IBB ETFs performed in 2026?

As of July 24, 2026, IDNA is up 22.74% year-to-date (YTD), while IBB has returned 11.58%. That puts IDNA better performer ahead so far this year.

Which ETF is attracting more investor money: IDNA or IBB?

Year-to-date, the IDNA ETF saw +$29M in flows, compared to +$89M for IBB.

Which ETF is more volatile: IDNA or IBB?

Over the past year, IDNA had a volatility of 23.9%, while IBB experienced 20.32%.

Which ETF is bigger: IDNA or IBB?

As of July 24, 2026, IDNA holds $188.81 M in assets under management (AUM), while IBB manages $9.34 B.

What sectors do the IDNA and IBB ETFs invest in?

IDNA leans toward sectors like Healthcare. Meanwhile, IBB focuses on Healthcare.

What are the top holdings of the IDNA ETF and IBB ETF?

IDNA top holdings include Twist Bioscience Corp., Moderna, Inc. and Bayer AG. IBB holds in its top three: Vertex Pharmaceuticals, Inc., Amgen, Inc. and Gilead Sciences, Inc..

IDNAvsIBBETF Comparison

iShares Genomics Immunology and Healthcare ETF

iShares Biotechnology ETF

IDNA vs IBB performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the IDNA and IBB ETFs performed in 2026?

As of July 24, 2026, IDNA is up 22.74% year-to-date (YTD), while IBB has returned 11.58%. That puts IDNA better performer ahead so far this year.

Which ETF is attracting more investor money: IDNA or IBB?

Year-to-date, the IDNA ETF saw +$29M in flows, compared to +$89M for IBB.

Which ETF is more volatile: IDNA or IBB?

Over the past year, IDNA had a volatility of 23.9%, while IBB experienced 20.32%.

Which ETF is bigger: IDNA or IBB?

As of July 24, 2026, IDNA holds $188.81 M in assets under management (AUM), while IBB manages $9.34 B.

What sectors do the IDNA and IBB ETFs invest in?

IDNA leans toward sectors like Healthcare. Meanwhile, IBB focuses on Healthcare.

What are the top holdings of the IDNA ETF and IBB ETF?

IDNA top holdings include Twist Bioscience Corp., Moderna, Inc. and Bayer AG. IBB holds in its top three: Vertex Pharmaceuticals, Inc., Amgen, Inc. and Gilead Sciences, Inc..

Which ETF is more diversified: IDNA or IBB?

IDNA holds 48 securities with 59.79% of its assets in the top 15. IBB has 242 securities and a top 15 weight of 53.71%.

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