IBBQvsIBBETF Comparison
VS
Invesco Nasdaq Biotechnology ETF (IBBQ) and iShares Biotechnology ETF (IBB) belong to the same industry segment: US Health Care. IBBQ's top 2 sector exposures are Healthcare and Non-Energy Materials. In contrast, IBB's top sector exposures are Healthcare, Non-Corporate and Non-Energy Materials. IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.44% for IBB. IBBQ is up 25.64% year-to-date (YTD) with +$38M in YTD flows. IBB performs better with 25.74% YTD performance, and +$593M in YTD flows. Run a side-by-side ETF comparison of IBBQ and IBB below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
Find out how industry players manage ETF portfolios. Discover our library of Model portfolios
IBBQ vs IBB performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBBQ IBB | +0.32%+0.63% | +9.87%+12.60% | +25.64%+25.74% | +36.17%+35.21% | +100.45%+90.01% | +50.62%+36.37% |
| Flows | IBBQ IBB | +$14M+$274M | +$35M+$504M | +$38M+$593M | +$55M+$1.82B | +$74M-$29M | +$52M-$961M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBBQ IBB | +25.72%+26.12% | +22.50%+22.65% | +21.20%+21.38% | +22.22%+22.58% |
| Max drawdown | IBBQ IBB | -8.58%-7.78% | -8.58%-9.61% | -23.78%-24.82% | -34.86%-35.62% |
| Max drawdown duration | IBBQ IBB | 69d69d | 69d151d | 375d377d | 1429d1468d |
Trading data
IBBQ | IBB | |
Last sale 10/28/2026 at 1:30 PM | $35.83 | $216.35 |
| Previous close 10/27/2026 | $35.38 | $212.20 |
| Consolidated volume 10/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
Create an account to view replication metrics
Join for free
IBBQ | IBB | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
Advertisement
Main metrics
Last update 10/28/2026 at 1:30 PM
Live
Closed
IBBQ | IBB | |
|---|---|---|
| Last price | $35.83 | $216.35 |
| 1D performance | +1.27% | +1.96% |
| AuM | $117.67 M | $11.03 B |
| E/R | 0.19% | 0.44% |
Advertisement
Exposure
Countries
IBBQ
USA
88.22%
Other
11.78%
IBB
USA
86.02%
Other
13.98%
Sectors
IBBQ
Healthcare
99.99%
Other
0.01%
IBB
Healthcare
99.9%
Other
0.1%
Advertisement
Diversification
IBBQ
Total weight of top 15 holdings out of 15
52.06%
IBB
Total weight of top 15 holdings out of 15
56.64%
Top 15 holdings
Data as of August 31, 2026
IBBQ
Amgen, Inc.
8.60%
Vertex Pharmaceuticals, Inc.
8.10%
Gilead Sciences, Inc.
7.34%
Regeneron Pharmaceuticals, Inc.
5.26%
Moderna, Inc.
3.58%
Revolution Medicines, Inc.
2.97%
Illumina, Inc.
2.18%
Biogen, Inc.
2.07%
Alnylam Pharmaceuticals, Inc.
2.00%
argenx SE
1.84%
Royalty Pharma Plc
1.73%
Roivant Sciences Ltd.
1.71%
Insmed, Inc.
1.66%
Incyte Corp.
1.61%
United Therapeutics Corp.
1.42%
IBB
Amgen, Inc.
8.45%
Vertex Pharmaceuticals, Inc.
8.05%
Gilead Sciences, Inc.
7.21%
Regeneron Pharmaceuticals, Inc.
5.72%
argenx SE
3.80%
Moderna, Inc.
3.62%
Natera, Inc.
3.12%
Revolution Medicines, Inc.
2.78%
Illumina, Inc.
2.29%
Alnylam Pharmaceuticals, Inc.
2.27%
Biogen, Inc.
2.25%
BeOne Medicines Ltd.
2.03%
Insmed, Inc.
1.85%
Incyte Corp.
1.73%
United Therapeutics Corp.
1.49%
Frequently asked questions about IBBQ and IBB
How have the IBBQ and IBB ETFs performed in 2026?
As of October 27, 2026, IBBQ is up 25.64% year-to-date (YTD), while IBB has returned 25.74%. That puts IBB better performer ahead so far this year.
Which ETF is attracting more investor money: IBBQ or IBB?
Year-to-date, the IBBQ ETF saw +$38M in flows, compared to +$593M for IBB.
Which ETF is more volatile: IBBQ or IBB?
Over the past year, IBBQ had a volatility of 22.5%, while IBB experienced 22.65%.
Which ETF is bigger: IBBQ or IBB?
As of October 27, 2026, IBBQ holds $117.67 M in assets under management (AUM), while IBB manages $11.03 B.
What sectors do the IBBQ and IBB ETFs invest in?
IBBQ leans toward sectors like Healthcare. Meanwhile, IBB focuses on Healthcare.
What are the top holdings of the IBBQ ETF and IBB ETF?
IBBQ top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc.. IBB holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..
Which ETF is more diversified: IBBQ or IBB?
IBBQ holds 249 securities with 52.06% of its assets in the top 15. IBB has 241 securities and a top 15 weight of 56.64%.
Advertisement
Latest news about IBBQ & IBB
Small-Cap Biotech ETFs: High-Risk, High-Reward Opportunities
September 18, 2025
IBB
Are Biotechnology ETFs In the Midst of a Comeback?
August 20, 2025
IBB
Investing in the Aging Population: A Look at Bonds and Pharma ETFs
March 27, 2023
IBB
Health is Wealth: A look at the Healthcare Sector
January 24, 2023
IBB
Advertisement
Biotech ETFs – Investing in Health Innovation
July 21, 2022
IBB
Biotech ETFs – Investing in Health Innovation
July 21, 2022
IBB
Advertisement
