IBBQvsIBBETF Comparison
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Invesco Nasdaq Biotechnology ETF (IBBQ) and iShares Biotechnology ETF (IBB) belong to the same industry segment: US Health Care. IBBQ's top 3 sector exposures are Health Care and Consumer Staples. In contrast, IBB's top sector exposures are Health Care IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.44% for IBB. IBBQ is up 3.49% year-to-date (YTD) with +$290K in YTD flows. IBB performs worse with 0.69% YTD performance, and -$200M in YTD flows. Run a side-by-side ETF comparison of IBBQ and IBB below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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IBBQ vs IBB performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBBQ IBB | +5.67%+5.04% | -0.91%-3.38% | +3.49%+0.69% | +41.67%+37.00% | +41.72%+28.67% | n/a+8.66% |
| Flows | IBBQ IBB | -$8M+$241M | -$9M-$196M | +$290K-$200M | +$14M+$775M | +$34M-$1.51B | --$1.91B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBBQ IBB | +22.23%+22.36% | +21.05%+21.19% | +19.62%+19.80% | n/a+22.08% |
| Max drawdown | IBBQ IBB | -8.38%-9.27% | -8.39%-9.61% | -23.78%-24.82% | n/a-39.75% |
| Max drawdown duration | IBBQ IBB | 48d87d | 33d92d | 375d377d | n/a1611d |
Trading data
IBBQ | IBB | |
Last sale 4/27/2026 at 1:30 PM | $29.33 | $169.02 |
| Previous close 04/24/2026 | $29.34 | $169.78 |
| Consolidated volume 04/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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IBBQ | IBB | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/27/2026 at 1:30 PM
Live
Closed
IBBQ | IBB | |
|---|---|---|
| Last price | $29.33 | $169.02 |
| 1D performance | -0.02% | -0.45% |
| AuM | $66.29 M | $8.19 B |
| E/R | 0.19% | 0.44% |
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Exposure
Countries
IBBQ
USA
92.77%
Other
7.23%
IBB
USA
95.97%
Other
4.03%
Sectors
IBBQ
Health Care
85.9%
Other
14.1%
IBB
Health Care
85.68%
Other
14.32%
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Diversification
IBBQ
Total weight of top 15 holdings out of 15
51.37%
IBB
Total weight of top 15 holdings out of 15
55.88%
Top 15 holdings
Data as of March 31, 2026
IBBQ
GILEAD SCIENCES
7.85%
AMGEN-T
7.82%
VERTEX PHARMACEUTICALS
7.59%
REGENERON PHARMACEUTICALS
6.48%
ALNYLAM PHARMACEUTICALS
3.56%
INSMED
2.65%
BIOGEN INC
2.28%
UTD THERAPEUT
1.94%
ROYALTY PHARMA
1.68%
US04016X1019
1.66%
MODERNA INC
1.66%
ROIVANT SCIENCES LTD
1.61%
REVOLUTION MEDICINES INC
1.55%
ILLUMINA
1.52%
INCYTE
1.52%
IBB
GILEAD SCIENCES
7.75%
AMGEN-T
7.51%
VERTEX PHARMACEUTICALS
7.44%
REGENERON PHARMACEUTICALS
7.21%
ALNYLAM PHARMACEUTICALS
3.99%
INSMED
3.20%
US04016X1019
3.07%
BIOGEN INC
2.46%
NATERA
2.41%
UTD THERAPEUT
2.30%
US07725L1026
1.93%
INCYTE
1.70%
MODERNA INC
1.68%
ILLUMINA
1.68%
REVOLUTION MEDICINES INC
1.54%
Frequently asked questions about IBBQ and IBB
How have the IBBQ and IBB ETFs performed in 2026?
As of April 24, 2026, IBBQ is up 3.49% year-to-date (YTD), while IBB has returned 0.69%. That puts IBBQ better performer ahead so far this year.
Which ETF is attracting more investor money: IBBQ or IBB?
Year-to-date, the IBBQ ETF saw +$290K in flows, compared to -$200M for IBB.
Which ETF is more volatile: IBBQ or IBB?
Over the past year, IBBQ had a volatility of 21.05%, while IBB experienced 21.19%.
Which ETF is bigger: IBBQ or IBB?
As of April 24, 2026, IBBQ holds $66.29 M in assets under management (AUM), while IBB manages $8.19 B.
What sectors do the IBBQ and IBB ETFs invest in?
IBBQ leans toward sectors like Health Care. Meanwhile, IBB focuses on Health Care.
What are the top holdings of the IBBQ ETF and IBB ETF?
IBBQ top holdings include GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS. IBB holds in its top three: GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS.
Which ETF is more diversified: IBBQ or IBB?
IBBQ holds 256 securities with 51.37% of its assets in the top 15. IBB has 249 securities and a top 15 weight of 55.88%.
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