IBBvsWDNAETF Comparison
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iShares Biotechnology ETF (IBB) belongs to the US Health Care segment. WisdomTree BioRevolution Fund (WDNA) is part of the BioTech & Genomics segment. IBB's top 3 sector exposures are Healthcare, Non-Corporate and Non-Energy Materials. In contrast, WDNA's top sector exposures are Healthcare, Non-Energy Materials and Consumer Non-Cyclicals. IBB is less expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.45% for WDNA. IBB is up 20.29% year-to-date (YTD) with +$363M in YTD flows. WDNA performs better with 31.07% YTD performance, and +$326K in YTD flows. Run a side-by-side ETF comparison of IBB and WDNA below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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IBB vs WDNA performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/11/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBB WDNA | +1.54%+4.43% | +19.02%+23.49% | +20.29%+31.07% | +41.46%+55.75% | +60.28%+44.20% | +20.74%-11.83% |
| Flows | IBB WDNA | +$288M+$683K | +$782M+$683K | +$363M+$326K | +$1.85B+$326K | -$558M+$159K | -$1.34B+$2M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBB WDNA | +24.01%+34.24% | +21.76%+28.01% | +21.05%+26.29% | +22.47%+25.74% |
| Max drawdown | IBB WDNA | -6.57%-9.35% | -9.61%-11.90% | -24.82%-36.45% | -38.96%-57.38% |
| Max drawdown duration | IBB WDNA | 23d42d | 151d147d | 377d595d | 1523d1814d |
Trading data
IBB | WDNA | |
Last sale 9/11/2026 at 1:30 PM | $202.93 | $22.14 |
| Previous close 09/10/2026 | $202.64 | $22.11 |
| Consolidated volume 09/10/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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IBB | WDNA | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/11/2026 at 1:30 PM
Live
Closed
IBB | WDNA | |
|---|---|---|
| Last price | $202.93 | $22.14 |
| 1D performance | +0.14% | +0.13% |
| AuM | $10.34 B | $3.55 M |
| E/R | 0.44% | 0.45% |
Characteristics
IBB | WDNA | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | iShares | WisdomTree |
| Benchmark | ICE Biotechnology Index | WisdomTree BioRevolution Index |
| N° of holdings | 240 | 79 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | February 5, 2001 | June 3, 2021 |
| ESG | No | No |
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Exposure
Countries
IBB
USA
86.04%
Other
13.96%
WDNA
USA
83.75%
Other
16.25%
Sectors
IBB
Healthcare
99.83%
Other
0.17%
WDNA
Healthcare
88.38%
Non-Energy Materi.
7.38%
Other
4.25%
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Diversification
IBB
Total weight of top 15 holdings out of 15
54.48%
WDNA
Total weight of top 15 holdings out of 15
40.46%
Top 15 holdings
Data as of July 31, 2026
IBB
Amgen, Inc.
8.42%
Vertex Pharmaceuticals, Inc.
7.87%
Gilead Sciences, Inc.
7.14%
Regeneron Pharmaceuticals, Inc.
5.84%
argenx SE
3.55%
Natera, Inc.
2.88%
Revolution Medicines, Inc.
2.87%
Illumina, Inc.
2.42%
Biogen, Inc.
2.38%
Alnylam Pharmaceuticals, Inc.
2.14%
BeOne Medicines Ltd.
2.01%
Incyte Corp.
1.91%
Insmed, Inc.
1.71%
United Therapeutics Corp.
1.69%
Moderna, Inc.
1.65%
WDNA
Twist Bioscience Corp.
5.53%
Eli Lilly & Co.
4.11%
Moderna, Inc.
3.59%
Johnson & Johnson
3.13%
Immunome, Inc.
2.57%
United Therapeutics Corp.
2.50%
10X Genomics, Inc.
2.44%
Natera, Inc.
2.42%
Darling Ingredients, Inc.
2.26%
Corteva, Inc.
2.19%
Structure Therapeutics, Inc.
2.04%
Stoke Therapeutics, Inc.
2.02%
Krystal Biotech, Inc.
2.01%
Thermo Fisher Scientific, Inc.
1.83%
Tempus AI, Inc.
1.82%
Frequently asked questions about IBB and WDNA
How have the IBB and WDNA ETFs performed in 2026?
As of September 11, 2026, IBB is up 20.29% year-to-date (YTD), while WDNA has returned 31.07%. That puts WDNA better performer ahead so far this year.
Which ETF is attracting more investor money: IBB or WDNA?
Year-to-date, the IBB ETF saw +$363M in flows, compared to +$326K for WDNA.
Which ETF is more volatile: IBB or WDNA?
Over the past year, IBB had a volatility of 21.76%, while WDNA experienced 28.01%.
Which ETF is bigger: IBB or WDNA?
As of September 11, 2026, IBB holds $10.34 B in assets under management (AUM), while WDNA manages $3.55 M.
What sectors do the IBB and WDNA ETFs invest in?
IBB leans toward sectors like Healthcare. Meanwhile, WDNA focuses on Healthcare and Non-Energy Materials.
What are the top holdings of the IBB ETF and WDNA ETF?
IBB top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc.. WDNA holds in its top three: Twist Bioscience Corp., Eli Lilly & Co. and Moderna, Inc..
Which ETF is more diversified: IBB or WDNA?
IBB holds 241 securities with 54.48% of its assets in the top 15. WDNA has 79 securities and a top 15 weight of 40.46%.
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