IBBvsTMEDETF Comparison
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iShares Biotechnology ETF (IBB) and T. Rowe Price Health Care ETF (TMED) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. Both IBB and TMED have the same Total Expense Ratio (TER) of 0.44%. IBB is up 0.16% year-to-date (YTD) with -$327M in YTD flows. TMED performs worse with -0.2% YTD performance, and +$3M in YTD flows. Run a side-by-side ETF comparison of IBB and TMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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IBB vs TMED performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBB TMED | +5.31%+7.12% | -4.45%-1.63% | +0.16%-0.20% | +35.85%n/a | +31.87%n/a | +8.56%n/a |
| Flows | IBB TMED | -$138M-$41K | -$331M+$3M | -$327M+$3M | +$772M- | -$1.59B- | -$2.08B- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBB TMED | +22.34%+20.92% | +21.20%n/a | +19.78%n/a | +22.09%n/a |
| Max drawdown | IBB TMED | -9.27%-9.37% | -9.61%n/a | -24.82%n/a | -39.75%n/a |
| Max drawdown duration | IBB TMED | 90d46d | 95dn/a | 377dn/a | 1611dn/a |
Trading data
IBB | TMED | |
Last sale 4/29/2026 at 5:13 PM | $164.64 | $29.28 |
| Previous close 04/28/2026 | $167.81 | $29.56 |
| Consolidated volume 04/28/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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TMED
is actively managed and doesn’t replicate an indexIBB | TMED | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/29/2026 at 5:13 PM
Live
Closed
IBB | TMED | |
|---|---|---|
| Last price | $164.64 | $29.28 |
| 1D performance | -1.89% | -0.96% |
| AuM | $8.03 B | $19.25 M |
| E/R | 0.44% | 0.44% |
Characteristics
IBB | TMED | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | iShares | T. Rowe Price |
| Benchmark | ICE Biotechnology Index | - |
| N° of holdings | 179 | 76 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | February 5, 2001 | June 11, 2025 |
| ESG | No | No |
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Exposure
Countries
IBB
USA
95.97%
Other
4.03%
TMED
USA
82.66%
Other
17.34%
Sectors
IBB
Health Care
85.68%
Other
14.32%
TMED
Health Care
85.09%
Other
14.91%
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Diversification
IBB
Total weight of top 15 holdings out of 15
55.88%
TMED
Total weight of top 15 holdings out of 15
52.88%
Top 15 holdings
Data as of March 31, 2026
IBB
GILEAD SCIENCES
7.75%
AMGEN-T
7.51%
VERTEX PHARMACEUTICALS
7.44%
REGENERON PHARMACEUTICALS
7.21%
ALNYLAM PHARMACEUTICALS
3.99%
INSMED
3.20%
US04016X1019
3.07%
BIOGEN INC
2.46%
NATERA
2.41%
UTD THERAPEUT
2.30%
US07725L1026
1.93%
INCYTE
1.70%
MODERNA INC
1.68%
ILLUMINA
1.68%
REVOLUTION MEDICINES INC
1.54%
TMED
LILLY
14.48%
UNITEDHEALTH GRP
6.54%
THERMO FISHER SCIENTIFIC
4.59%
GILEAD SCIENCES
4.14%
ABBOTT LABS
3.91%
DANAHER
2.73%
MEDTRONIC PLC
2.24%
ALNYLAM PHARMACEUTICALS
2.06%
STRYKER
2.00%
DYNE THERAPEUTICS INC
1.88%
WATERS
1.75%
BECTON DICKINSON AND CO
1.71%
AGILENT TECHNOLOGIES
1.69%
ELANCO ANIMAL HEALTH INC
1.59%
HUMANA
1.57%
Frequently asked questions about IBB and TMED
How have the IBB and TMED ETFs performed in 2026?
As of April 27, 2026, IBB is up 0.16% year-to-date (YTD), while TMED has lost -0.2%. That puts IBB better performer ahead so far this year.
Which ETF is attracting more investor money: IBB or TMED?
Year-to-date, the IBB ETF saw -$327M in flows, compared to +$3M for TMED.
Which ETF is bigger: IBB or TMED?
As of April 27, 2026, IBB holds $8.03 B in assets under management (AUM), while TMED manages $19.25 M.
What sectors do the IBB and TMED ETFs invest in?
IBB leans toward sectors like Health Care. Meanwhile, TMED focuses on Health Care.
What are the top holdings of the IBB ETF and TMED ETF?
IBB top holdings include GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS. TMED holds in its top three: LILLY, UNITEDHEALTH GRP and THERMO FISHER SCIENTIFIC.
Which ETF is more diversified: IBB or TMED?
IBB holds 249 securities with 55.88% of its assets in the top 15. TMED has 82 securities and a top 15 weight of 52.88%.
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