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IBBvsIBBQETF Comparison

ETF 1

IBB

iShares Biotechnology ETF

This fund is part of

US Health Care

-0.12%

Full IBB fund page

VS

ETF 2

IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of

US Health Care

-0.12%

Full IBBQ fund page

iShares Biotechnology ETF (IBB) and Invesco Nasdaq Biotechnology ETF (IBBQ) belong to the same industry segment: US Health Care. IBB's top 3 sector exposures are Healthcare, Non-Corporate and Non-Energy Materials. In contrast, IBBQ's top sector exposures are Healthcare and Non-Energy Materials. IBB is more expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.19% for IBBQ. IBB is up 20.29% year-to-date (YTD) with +$363M in YTD flows. IBBQ performs better with 21.59% YTD performance, and +$19M in YTD flows. Run a side-by-side ETF comparison of IBB and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IBB vs IBBQ performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 09/11/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	IBB IBBQ	+1.54%+0.96%	+19.02%+20.13%	+20.29%+21.59%	+41.46%+46.11%	+60.28%+72.17%	+20.74%+33.51%
Flows	IBB IBBQ	+$288M+$15M	+$782M+$18M	+$363M+$19M	+$1.85B+$38M	-$558M+$54M	-$1.34B+$28M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	IBB IBBQ	+24.01%+24.15%	+21.76%+21.65%	+21.05%+20.89%	+22.47%+22.08%
Max drawdown	IBB IBBQ	-6.57%-6.48%	-9.61%-8.38%	-24.82%-23.78%	-38.96%-37.23%
Max drawdown duration	IBB IBBQ	23d22d	151d48d	377d375d	1523d1485d

Trading data

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	IBB	IBBQ
Last sale 9/11/2026 at 1:30 PM	$202.93	$34.47
Previous close 09/10/2026	$202.64	$34.41
Consolidated volume 09/10/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of August 31, 2026

1-year trailing difference

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	IBB	IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 9/11/2026 at 1:30 PM

Live

Closed

	IBB	IBBQ
Last price	$202.93	$34.47
1D performance	+0.14%	+0.18%
AuM	$10.34 B	$95.70 M
E/R	0.44%	0.19%

Characteristics

	IBB	IBBQ
Management strategy	Passive	Passive
Provider	iShares	Invesco
Benchmark	ICE Biotechnology Index	NASDAQ Biotechnology Index
N° of holdings	240	249
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	February 5, 2001	June 9, 2021
ESG	No	No

More IBB data on Trackinsight

More IBBQ data on Trackinsight

Exposure

Countries

IBB

USA

86.04%

Other

13.96%

IBBQ

USA

88.05%

Other

11.95%

Sectors

IBB

Healthcare

99.83%

Other

0.17%

IBBQ

Healthcare

99.91%

Other

0.09%

Diversification

IBB

Total weight of top 15 holdings out of 15

54.48%

IBBQ

Total weight of top 15 holdings out of 15

50.47%

Top 15 holdings

Data as of July 31, 2026

IBB

Amgen, Inc.

8.42%

Vertex Pharmaceuticals, Inc.

7.87%

Gilead Sciences, Inc.

7.14%

Regeneron Pharmaceuticals, Inc.

5.84%

argenx SE

3.55%

Natera, Inc.

2.88%

Revolution Medicines, Inc.

2.87%

Illumina, Inc.

2.42%

Biogen, Inc.

2.38%

Alnylam Pharmaceuticals, Inc.

2.14%

BeOne Medicines Ltd.

2.01%

Incyte Corp.

1.91%

Insmed, Inc.

1.71%

United Therapeutics Corp.

1.69%

Moderna, Inc.

1.65%

IBBQ

Amgen, Inc.

8.55%

Vertex Pharmaceuticals, Inc.

8.03%

Gilead Sciences, Inc.

7.34%

Regeneron Pharmaceuticals, Inc.

5.08%

Revolution Medicines, Inc.

2.73%

Alnylam Pharmaceuticals, Inc.

2.71%

Biogen, Inc.

2.19%

Illumina, Inc.

2.09%

Royalty Pharma Plc

1.86%

Incyte Corp.

1.80%

argenx SE

1.73%

Roivant Sciences Ltd.

1.68%

Insmed, Inc.

1.58%

United Therapeutics Corp.

1.58%

Moderna, Inc.

1.53%

Frequently asked questions about IBB and IBBQ

How have the IBB and IBBQ ETFs performed in 2026?

As of September 11, 2026, IBB is up 20.29% year-to-date (YTD), while IBBQ has returned 21.59%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: IBB or IBBQ?

Year-to-date, the IBB ETF saw +$363M in flows, compared to +$19M for IBBQ.

Which ETF is more volatile: IBB or IBBQ?

Over the past year, IBB had a volatility of 21.76%, while IBBQ experienced 21.65%.

Which ETF is bigger: IBB or IBBQ?

As of September 11, 2026, IBB holds $10.34 B in assets under management (AUM), while IBBQ manages $95.70 M.

What sectors do the IBB and IBBQ ETFs invest in?

IBB leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.

What are the top holdings of the IBB ETF and IBBQ ETF?

IBB top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc.. IBBQ holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..

IBBvsIBBQETF Comparison

iShares Biotechnology ETF

Invesco Nasdaq Biotechnology ETF

IBB vs IBBQ performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the IBB and IBBQ ETFs performed in 2026?

As of September 11, 2026, IBB is up 20.29% year-to-date (YTD), while IBBQ has returned 21.59%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: IBB or IBBQ?

Year-to-date, the IBB ETF saw +$363M in flows, compared to +$19M for IBBQ.

Which ETF is more volatile: IBB or IBBQ?

Over the past year, IBB had a volatility of 21.76%, while IBBQ experienced 21.65%.

Which ETF is bigger: IBB or IBBQ?

As of September 11, 2026, IBB holds $10.34 B in assets under management (AUM), while IBBQ manages $95.70 M.

What sectors do the IBB and IBBQ ETFs invest in?

IBB leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.

What are the top holdings of the IBB ETF and IBBQ ETF?

IBB top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc.. IBBQ holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..

Which ETF is more diversified: IBB or IBBQ?

IBB holds 241 securities with 54.48% of its assets in the top 15. IBBQ has 249 securities and a top 15 weight of 50.47%.

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