IBBvsIBBQETF Comparison
VS
iShares Biotechnology ETF (IBB) and Invesco Nasdaq Biotechnology ETF (IBBQ) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. IBB is more expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.19% for IBBQ. IBB is down -1.05% year-to-date (YTD) with -$511M in YTD flows. IBBQ performs better with 1.62% YTD performance, and +$290K in YTD flows. Run a side-by-side ETF comparison of IBB and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
Find out how industry players manage ETF portfolios. Discover our library of Model portfolios
IBB vs IBBQ performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/08/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBB IBBQ | -1.76%-2.28% | -2.48%-1.78% | -1.05%+1.62% | +31.10%+36.18% | +30.39%+41.73% | +6.87%+17.80% |
| Flows | IBB IBBQ | -$107M- | -$447M-$8M | -$511M+$290K | +$792M+$15M | -$1.52B+$33M | -$2.45B+$59M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBB IBBQ | +23.84%+23.94% | +20.10%+20.06% | +20.12%+19.94% | +22.17%+21.86% |
| Max drawdown | IBB IBBQ | -7.21%-6.92% | -9.61%-8.38% | -24.82%-23.78% | -39.75%-38.09% |
| Max drawdown duration | IBB IBBQ | 50d50d | 137d48d | 377d375d | 1611d1543d |
Trading data
IBB | IBBQ | |
Last sale 6/9/2026 at 1:30 PM | $169.36 | $29.25 |
| Previous close 06/08/2026 | $166.92 | $28.77 |
| Consolidated volume 06/08/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
Create an account to view replication metrics
Join for free
IBB | IBBQ | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
Advertisement
Main metrics
Last update 6/9/2026 at 1:30 PM
Live
Closed
IBB | IBBQ | |
|---|---|---|
| Last price | $169.36 | $29.25 |
| 1D performance | +1.46% | +1.67% |
| AuM | $7.74 B | $65.09 M |
| E/R | 0.44% | 0.19% |
Advertisement
Exposure
Countries
IBB
USA
94.92%
Other
5.08%
IBBQ
USA
91.42%
Other
8.58%
Sectors
IBB
Health Care
84.68%
Other
15.32%
IBBQ
Health Care
84.62%
Other
15.38%
Advertisement
Diversification
IBB
Total weight of top 15 holdings out of 15
55.04%
IBBQ
Total weight of top 15 holdings out of 15
49.38%
Top 15 holdings
Data as of April 30, 2026
IBB
AMGEN-T
7.46%
GILEAD SCIENCES
7.35%
VERTEX PHARMACEUTICALS
7.20%
REGENERON PHARMACEUTICALS
6.67%
ALNYLAM PHARMACEUTICALS
3.77%
US04016X1019
3.32%
INSMED
2.69%
BIOGEN INC
2.57%
NATERA
2.51%
REVOLUTION MEDICINES INC
2.30%
UTD THERAPEUT
2.24%
US07725L1026
1.94%
ILLUMINA
1.74%
INCYTE
1.74%
MODERNA INC
1.54%
IBBQ
AMGEN-T
7.26%
GILEAD SCIENCES
7.11%
VERTEX PHARMACEUTICALS
7.11%
REGENERON PHARMACEUTICALS
6.23%
ALNYLAM PHARMACEUTICALS
3.30%
INSMED
2.36%
BIOGEN INC
2.14%
REVOLUTION MEDICINES INC
2.10%
UTD THERAPEUT
2.00%
US04016X1019
1.79%
ROYALTY PHARMA
1.71%
ROIVANT SCIENCES LTD
1.60%
ILLUMINA
1.58%
MODERNA INC
1.55%
INCYTE
1.53%
Frequently asked questions about IBB and IBBQ
How have the IBB and IBBQ ETFs performed in 2026?
As of June 8, 2026, IBB is down -1.05% year-to-date (YTD), while IBBQ has returned 1.62%. That puts IBBQ better performer ahead so far this year.
Which ETF is attracting more investor money: IBB or IBBQ?
Year-to-date, the IBB ETF saw -$511M in flows, compared to +$290K for IBBQ.
Which ETF is more volatile: IBB or IBBQ?
Over the past year, IBB had a volatility of 20.1%, while IBBQ experienced 20.06%.
Which ETF is bigger: IBB or IBBQ?
As of June 8, 2026, IBB holds $7.74 B in assets under management (AUM), while IBBQ manages $65.09 M.
What sectors do the IBB and IBBQ ETFs invest in?
IBB leans toward sectors like Health Care. Meanwhile, IBBQ focuses on Health Care.
What are the top holdings of the IBB ETF and IBBQ ETF?
IBB top holdings include AMGEN-T, GILEAD SCIENCES and VERTEX PHARMACEUTICALS. IBBQ holds in its top three: AMGEN-T, GILEAD SCIENCES and VERTEX PHARMACEUTICALS.
Which ETF is more diversified: IBB or IBBQ?
IBB holds 246 securities with 55.04% of its assets in the top 15. IBBQ has 255 securities and a top 15 weight of 49.38%.
Advertisement
Latest news about IBB & IBBQ
Small-Cap Biotech ETFs: High-Risk, High-Reward Opportunities
September 18, 2025
IBB
Are Biotechnology ETFs In the Midst of a Comeback?
August 20, 2025
IBB
Investing in the Aging Population: A Look at Bonds and Pharma ETFs
March 27, 2023
IBB
Health is Wealth: A look at the Healthcare Sector
January 24, 2023
IBB
Advertisement
Biotech ETFs – Investing in Health Innovation
July 21, 2022
IBB
Biotech ETFs – Investing in Health Innovation
July 21, 2022
IBB
Advertisement
