IBBvsIBBQETF Comparison
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iShares Biotechnology ETF (IBB) and Invesco Nasdaq Biotechnology ETF (IBBQ) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. IBB is more expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.19% for IBBQ. IBB is up 0.88% year-to-date (YTD) with -$205M in YTD flows. IBBQ performs better with 3.06% YTD performance, and +$6M in YTD flows. Run a side-by-side ETF comparison of IBB and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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IBB vs IBBQ performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/01/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBB IBBQ | -2.15%-2.22% | +0.73%+3.07% | +0.88%+3.06% | +37.01%+43.04% | +32.25%+44.71% | +13.73%n/a |
| Flows | IBB IBBQ | -$320M-$2M | -$205M+$6M | -$205M+$6M | +$622M+$18M | -$1.58B+$39M | -$2.13B- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBB IBBQ | +23.89%+23.74% | +23.96%+23.55% | +19.74%+19.56% | +22.09%n/a |
| Max drawdown | IBB IBBQ | -9.61%-8.38% | -11.66%-11.33% | -24.82%-23.78% | -39.75%n/a |
| Max drawdown duration | IBB IBBQ | 69d36d | 64d27d | 377d375d | 1611dn/a |
Trading data
IBB | IBBQ | |
Last sale 4/2/2026 at 6:41 PM | $168.80 | $28.83 |
| Previous close 04/01/2026 | $170.13 | $29.21 |
| Consolidated volume 04/01/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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IBB | IBBQ | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/2/2026 at 6:41 PM
Live
Closed
IBB | IBBQ | |
|---|---|---|
| Last price | $168.80 | $28.83 |
| 1D performance | -0.78% | -1.30% |
| AuM | $8.20 B | $71.27 M |
| E/R | 0.44% | 0.19% |
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Exposure
Countries
IBB
USA
96.06%
Other
3.94%
IBBQ
USA
93.25%
Other
6.75%
Sectors
IBB
Health Care
86.04%
Other
13.96%
IBBQ
Health Care
86.48%
Other
13.52%
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Diversification
IBB
Total weight of top 15 holdings out of 15
57.44%
IBBQ
Total weight of top 15 holdings out of 15
53.51%
Top 15 holdings
Data as of February 28, 2026
IBB
GILEAD SCIENCES
9.16%
VERTEX PHARMACEUTICALS
8.88%
AMGEN-T
8.81%
REGENERON PHARMACEUTICALS
6.68%
ALNYLAM PHARMACEUTICALS
3.68%
INSMED
2.70%
US04016X1019
2.68%
NATERA
2.43%
BIOGEN INC
2.36%
US07725L1026
2.00%
UTD THERAPEUT
1.79%
INCYTE
1.67%
ILLUMINA
1.62%
MODERNA INC
1.54%
REVOLUTION MEDICINES INC
1.45%
IBBQ
GILEAD SCIENCES
9.37%
VERTEX PHARMACEUTICALS
9.08%
AMGEN-T
9.00%
REGENERON PHARMACEUTICALS
6.00%
ALNYLAM PHARMACEUTICALS
3.30%
INSMED
2.41%
BIOGEN INC
2.08%
US04016X1019
1.70%
UTD THERAPEUT
1.64%
MODERNA INC
1.52%
ROIVANT SCIENCES LTD
1.50%
REVOLUTION MEDICINES INC
1.49%
INCYTE
1.48%
ILLUMINA
1.47%
ROYALTY PHARMA
1.46%
Frequently asked questions about IBB and IBBQ
How have the IBB and IBBQ ETFs performed in 2026?
As of April 1, 2026, IBB is up 0.88% year-to-date (YTD), while IBBQ has returned 3.06%. That puts IBBQ better performer ahead so far this year.
Which ETF is attracting more investor money: IBB or IBBQ?
Year-to-date, the IBB ETF saw -$205M in flows, compared to +$6M for IBBQ.
Which ETF is more volatile: IBB or IBBQ?
Over the past year, IBB had a volatility of 23.96%, while IBBQ experienced 23.55%.
Which ETF is bigger: IBB or IBBQ?
As of April 1, 2026, IBB holds $8.20 B in assets under management (AUM), while IBBQ manages $71.27 M.
What sectors do the IBB and IBBQ ETFs invest in?
IBB leans toward sectors like Health Care. Meanwhile, IBBQ focuses on Health Care.
What are the top holdings of the IBB ETF and IBBQ ETF?
IBB top holdings include GILEAD SCIENCES, VERTEX PHARMACEUTICALS and AMGEN-T. IBBQ holds in its top three: GILEAD SCIENCES, VERTEX PHARMACEUTICALS and AMGEN-T.
Which ETF is more diversified: IBB or IBBQ?
IBB holds 253 securities with 57.44% of its assets in the top 15. IBBQ has 260 securities and a top 15 weight of 53.51%.
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