IBBvsGNOMETF Comparison
VS
iShares Biotechnology ETF (IBB) belongs to the US Health Care segment. Global X Genomics & Biotechnology ETF - USD (GNOM) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. IBB is less expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.5% for GNOM. IBB is down -1.92% year-to-date (YTD) with -$327M in YTD flows. GNOM performs worse with -3.59% YTD performance, and -$602K in YTD flows. Run a side-by-side ETF comparison of IBB and GNOM below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
Find out how industry players manage ETF portfolios. Discover our library of Model portfolios
IBB vs GNOM performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/29/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBB GNOM | +2.22%+5.91% | -5.02%-9.39% | -1.92%-3.59% | +32.88%+37.04% | +26.75%-9.93% | +8.28%-51.34% |
| Flows | IBB GNOM | -$130M-$829K | -$358M+$1M | -$327M-$602K | +$716M-$14M | -$1.52B-$106M | -$2.23B+$100K |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBB GNOM | +22.30%+28.63% | +21.23%+27.27% | +19.79%+28.80% | +22.09%+33.22% |
| Max drawdown | IBB GNOM | -8.43%-14.55% | -9.61%-18.16% | -24.82%-46.50% | -39.75%-72.17% |
| Max drawdown duration | IBB GNOM | 43d90d | 97d97d | 377d1080d | 1611d1763d |
Trading data
IBB | GNOM | |
Last sale 5/1/2026 at 1:30 PM | $167.45 | $45.36 |
| Previous close 04/29/2026 | $165.38 | $43.95 |
| Consolidated volume 04/29/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of April 29, 2026
1-year trailing difference
Create an account to view replication metrics
Join for free
IBB | GNOM | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
Advertisement
Main metrics
Last update 5/1/2026 at 1:30 PM
Live
Closed
IBB | GNOM | |
|---|---|---|
| Last price | $167.45 | $45.36 |
| 1D performance | +1.25% | +3.22% |
| AuM | $7.86 B | $49.38 M |
| E/R | 0.44% | 0.5% |
Advertisement
Exposure
Countries
IBB
USA
95.97%
Other
4.03%
GNOM
USA
87.57%
Other
12.43%
Sectors
IBB
Health Care
85.68%
Other
14.32%
GNOM
Health Care
88.49%
Other
11.51%
Advertisement
Diversification
IBB
Total weight of top 15 holdings out of 15
55.88%
GNOM
Total weight of top 15 holdings out of 15
66.21%
Top 15 holdings
Data as of March 31, 2026
IBB
GILEAD SCIENCES
7.75%
AMGEN-T
7.51%
VERTEX PHARMACEUTICALS
7.44%
REGENERON PHARMACEUTICALS
7.21%
ALNYLAM PHARMACEUTICALS
3.99%
INSMED
3.20%
US04016X1019
3.07%
BIOGEN INC
2.46%
NATERA
2.41%
UTD THERAPEUT
2.30%
US07725L1026
1.93%
INCYTE
1.70%
MODERNA INC
1.68%
ILLUMINA
1.68%
REVOLUTION MEDICINES INC
1.54%
GNOM
MODERNA INC
8.48%
ARROWHEAD PHARMACEUTICALS INC
6.21%
US74006W2070
6.13%
ILLUMINA
5.52%
GUARDANT HEALTH INC
5.18%
VERTEX PHARMACEUTICALS
4.61%
BIOMARIN PHARMACEUTICAL
4.59%
NATERA
4.21%
BIO-TECHNE CORP
3.64%
BIONTECH SE ADR
3.58%
CRISPR THERAPEUTICS
3.08%
BRISTOL-MYERS SQUIBB
3.05%
ALNYLAM PHARMACEUTICALS
2.85%
TWIST BIOSCIENCE CORP
2.54%
ASTRAZENECA
2.53%
Frequently asked questions about IBB and GNOM
How have the IBB and GNOM ETFs performed in 2026?
As of April 29, 2026, IBB is down -1.92% year-to-date (YTD), while GNOM has lost -3.59%. That puts IBB better performer ahead so far this year.
Which ETF is attracting more investor money: IBB or GNOM?
Year-to-date, the IBB ETF saw -$327M in flows, compared to -$602K for GNOM.
Which ETF is more volatile: IBB or GNOM?
Over the past year, IBB had a volatility of 21.23%, while GNOM experienced 27.27%.
Which ETF is bigger: IBB or GNOM?
As of April 29, 2026, IBB holds $7.86 B in assets under management (AUM), while GNOM manages $49.38 M.
What sectors do the IBB and GNOM ETFs invest in?
IBB leans toward sectors like Health Care. Meanwhile, GNOM focuses on Health Care.
What are the top holdings of the IBB ETF and GNOM ETF?
IBB top holdings include GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS. GNOM holds in its top three: MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070.
Which ETF is more diversified: IBB or GNOM?
IBB holds 249 securities with 55.88% of its assets in the top 15. GNOM has 47 securities and a top 15 weight of 66.21%.
Advertisement
Latest news about IBB & GNOM
Small-Cap Biotech ETFs: High-Risk, High-Reward Opportunities
September 18, 2025
IBB
Are Biotechnology ETFs In the Midst of a Comeback?
August 20, 2025
IBB
Investing in the Aging Population: A Look at Bonds and Pharma ETFs
March 27, 2023
IBB
Health is Wealth: A look at the Healthcare Sector
January 24, 2023
IBB
Advertisement
Biotech ETFs – Investing in Health Innovation
July 21, 2022
IBB
Biotech ETFs – Investing in Health Innovation
July 21, 2022
IBB
Advertisement
