IBBvsGDOCETF Comparison
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iShares Biotechnology ETF (IBB) belongs to the US Health Care segment. Goldman Sachs Future Health Care Equity ETF (GDOC) is part of the Healthcare Technology segment. IBB's top 3 sector exposures are Healthcare, Non-Corporate and Non-Energy Materials. In contrast, GDOC's top sector exposures are Healthcare. IBB is less expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.75% for GDOC. IBB is up 28.25% year-to-date (YTD) with +$614M in YTD flows. GDOC performs worse with 7.08% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of IBB and GDOC below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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IBB vs GDOC performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/28/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBB GDOC | +2.64%+1.46% | +13.54%+5.33% | +28.25%+7.08% | +37.47%+11.24% | +92.71%+38.20% | +36.70%n/a |
| Flows | IBB GDOC | +$296M- | +$516M- | +$614M-$2M | +$1.83B-$2M | -$30M-$83M | -$947M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBB GDOC | +26.30%+15.38% | +22.73%+15.51% | +21.41%+14.98% | +22.59%n/a |
| Max drawdown | IBB GDOC | -7.78%-7.14% | -9.61%-15.39% | -24.82%-22.18% | -35.62%n/a |
| Max drawdown duration | IBB GDOC | 70d70d | 151d221d | 377d449d | 1468dn/a |
Trading data
IBB | GDOC | |
Last sale 10/28/2026 at 1:30 PM | $216.35 | $38.15 |
| Previous close 10/28/2026 | $212.20 | $37.86 |
| Consolidated volume 10/28/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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GDOC
is actively managed and doesn’t replicate an indexIBB | GDOC | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 10/28/2026 at 1:30 PM
Live
Closed
IBB | GDOC | |
|---|---|---|
| Last price | $216.35 | $38.15 |
| 1D performance | +1.96% | +0.75% |
| AuM | $11.27 B | $20.03 M |
| E/R | 0.44% | 0.75% |
Characteristics
IBB | GDOC | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | iShares | Goldman Sachs |
| Benchmark | NYSE Biotechnology Index | - |
| N° of holdings | 241 | 37 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | February 5, 2001 | November 11, 2021 |
| ESG | No | No |
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Exposure
Countries
IBB
USA
86.02%
Other
13.98%
GDOC
USA
80.11%
Other
19.89%
Sectors
IBB
Healthcare
99.9%
Other
0.1%
GDOC
Healthcare
97.08%
Other
2.92%
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Diversification
IBB
Total weight of top 15 holdings out of 15
56.64%
GDOC
Total weight of top 15 holdings out of 15
71.2%
Top 15 holdings
Data as of August 31, 2026
IBB
Amgen, Inc.
8.45%
Vertex Pharmaceuticals, Inc.
8.05%
Gilead Sciences, Inc.
7.21%
Regeneron Pharmaceuticals, Inc.
5.72%
argenx SE
3.80%
Moderna, Inc.
3.62%
Natera, Inc.
3.12%
Revolution Medicines, Inc.
2.78%
Illumina, Inc.
2.29%
Alnylam Pharmaceuticals, Inc.
2.27%
Biogen, Inc.
2.25%
BeOne Medicines Ltd.
2.03%
Insmed, Inc.
1.85%
Incyte Corp.
1.73%
United Therapeutics Corp.
1.49%
GDOC
Eli Lilly & Co.
12.25%
Johnson & Johnson
8.25%
Merck & Co., Inc.
7.53%
UnitedHealth Group, Inc.
5.82%
Guardant Health, Inc.
4.22%
Vertex Pharmaceuticals, Inc.
4.12%
argenx SE
4.11%
DexCom, Inc.
3.69%
Thermo Fisher Scientific, Inc.
3.52%
Agilent Technologies, Inc.
3.47%
Edwards Lifesciences Corp.
3.40%
Intuitive Surgical, Inc.
2.82%
Lonza Group AG
2.80%
Cencora, Inc.
2.65%
Roivant Sciences Ltd.
2.57%
Frequently asked questions about IBB and GDOC
How have the IBB and GDOC ETFs performed in 2026?
As of October 28, 2026, IBB is up 28.25% year-to-date (YTD), while GDOC has returned 7.08%. That puts IBB better performer ahead so far this year.
Which ETF is attracting more investor money: IBB or GDOC?
Year-to-date, the IBB ETF saw +$614M in flows, compared to -$2M for GDOC.
Which ETF is more volatile: IBB or GDOC?
Over the past year, IBB had a volatility of 22.73%, while GDOC experienced 15.51%.
Which ETF is bigger: IBB or GDOC?
As of October 28, 2026, IBB holds $11.27 B in assets under management (AUM), while GDOC manages $20.03 M.
What sectors do the IBB and GDOC ETFs invest in?
IBB leans toward sectors like Healthcare. Meanwhile, GDOC focuses on Healthcare.
What are the top holdings of the IBB ETF and GDOC ETF?
IBB top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc.. GDOC holds in its top three: Eli Lilly & Co., Johnson & Johnson and Merck & Co., Inc..
Which ETF is more diversified: IBB or GDOC?
IBB holds 241 securities with 56.64% of its assets in the top 15. GDOC has 37 securities and a top 15 weight of 71.2%.
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