IBBvsFXHETF Comparison
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iShares Biotechnology ETF (IBB) and First Trust Health Care AlphaDEX Fund ETF (FXH) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. IBB is less expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.61% for FXH. IBB is up 0.16% year-to-date (YTD) with -$327M in YTD flows. FXH performs worse with 0.02% YTD performance, and -$61M in YTD flows. Run a side-by-side ETF comparison of IBB and FXH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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IBB vs FXH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBB FXH | +5.31%+8.51% | -4.45%-2.07% | +0.16%+0.02% | +35.85%+15.45% | +31.87%+6.64% | +8.56%-0.20% |
| Flows | IBB FXH | -$138M-$5M | -$331M-$67M | -$327M-$61M | +$772M-$123M | -$1.59B-$719M | -$2.08B-$505M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBB FXH | +22.34%+17.05% | +21.20%+16.21% | +19.78%+15.23% | +22.09%+16.67% |
| Max drawdown | IBB FXH | -9.27%-9.86% | -9.61%-12.07% | -24.82%-17.89% | -39.75%-29.40% |
| Max drawdown duration | IBB FXH | 90d57d | 95d110d | 377d331d | 1611d1694d |
Trading data
IBB | FXH | |
Last sale 4/29/2026 at 1:30 PM | $165.38 | $111.91 |
| Previous close 04/28/2026 | $167.81 | $112.31 |
| Consolidated volume 04/28/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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IBB | FXH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/29/2026 at 1:30 PM
Live
Closed
IBB | FXH | |
|---|---|---|
| Last price | $165.38 | $111.91 |
| 1D performance | -1.45% | -0.36% |
| AuM | $8.03 B | $874.42 M |
| E/R | 0.44% | 0.61% |
Characteristics
IBB | FXH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | iShares | First Trust |
| Benchmark | ICE Biotechnology Index | StrataQuant Health Care Index |
| N° of holdings | 179 | 71 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | February 5, 2001 | May 8, 2007 |
| ESG | No | No |
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Exposure
Countries
IBB
USA
95.97%
Other
4.03%
FXH
USA
95.47%
Other
4.53%
Sectors
IBB
Health Care
85.68%
Other
14.32%
FXH
Health Care
93.76%
Other
6.24%
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Diversification
IBB
Total weight of top 15 holdings out of 15
55.88%
FXH
Total weight of top 15 holdings out of 15
35.37%
Top 15 holdings
Data as of March 31, 2026
IBB
GILEAD SCIENCES
7.75%
AMGEN-T
7.51%
VERTEX PHARMACEUTICALS
7.44%
REGENERON PHARMACEUTICALS
7.21%
ALNYLAM PHARMACEUTICALS
3.99%
INSMED
3.20%
US04016X1019
3.07%
BIOGEN INC
2.46%
NATERA
2.41%
UTD THERAPEUT
2.30%
US07725L1026
1.93%
INCYTE
1.70%
MODERNA INC
1.68%
ILLUMINA
1.68%
REVOLUTION MEDICINES INC
1.54%
FXH
ACADIA HEALTHCARE COMPANY
3.83%
APELLIS PHARMACEUTICALS
2.95%
PFIZER
2.63%
BIOGEN INC
2.40%
CARDINAL HEALTH
2.37%
HCA HEALTHCARE
2.33%
INCYTE
2.19%
IONIS PHARMACEUTICALS INC
2.18%
INSMED
2.17%
UTD THERAPEUT
2.15%
MERCK & CO INC
2.11%
LILLY
2.04%
NATERA
2.04%
MEDPACE HOLDINGS INC
2.00%
AMGEN-T
1.98%
Frequently asked questions about IBB and FXH
How have the IBB and FXH ETFs performed in 2026?
As of April 27, 2026, IBB is up 0.16% year-to-date (YTD), while FXH has returned 0.02%. That puts IBB better performer ahead so far this year.
Which ETF is attracting more investor money: IBB or FXH?
Year-to-date, the IBB ETF saw -$327M in flows, compared to -$61M for FXH.
Which ETF is more volatile: IBB or FXH?
Over the past year, IBB had a volatility of 21.2%, while FXH experienced 16.21%.
Which ETF is bigger: IBB or FXH?
As of April 27, 2026, IBB holds $8.03 B in assets under management (AUM), while FXH manages $874.42 M.
What sectors do the IBB and FXH ETFs invest in?
IBB leans toward sectors like Health Care. Meanwhile, FXH focuses on Health Care.
What are the top holdings of the IBB ETF and FXH ETF?
IBB top holdings include GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS. FXH holds in its top three: ACADIA HEALTHCARE COMPANY, APELLIS PHARMACEUTICALS and PFIZER.
Which ETF is more diversified: IBB or FXH?
IBB holds 249 securities with 55.88% of its assets in the top 15. FXH has 75 securities and a top 15 weight of 35.37%.
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