IBBvsFBTETF Comparison
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iShares Biotechnology ETF (IBB) and First Trust NYSE Arca Biotechnology Index Fund ETF (FBT) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. IBB is less expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.54% for FBT. IBB is up 0.16% year-to-date (YTD) with -$327M in YTD flows. FBT performs worse with -0.95% YTD performance, and +$1.07B in YTD flows. Run a side-by-side ETF comparison of IBB and FBT below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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IBB vs FBT performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBB FBT | +5.31%+7.20% | -4.45%-7.12% | +0.16%-0.95% | +35.85%+26.96% | +31.87%+35.51% | +8.56%+23.43% |
| Flows | IBB FBT | -$138M- | -$331M+$57M | -$327M+$1.07B | +$772M+$1.08B | -$1.59B+$617M | -$2.08B+$297M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBB FBT | +22.34%+23.35% | +21.20%+21.73% | +19.78%+20.18% | +22.09%+21.87% |
| Max drawdown | IBB FBT | -9.27%-13.36% | -9.61%-14.27% | -24.82%-19.92% | -39.75%-29.98% |
| Max drawdown duration | IBB FBT | 90d90d | 95d95d | 377d237d | 1611d1243d |
Trading data
IBB | FBT | |
Last sale 4/29/2026 at 7:22 PM | $165.27 | $200.59 |
| Previous close 04/28/2026 | $167.81 | $203.28 |
| Consolidated volume 04/28/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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IBB | FBT | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/29/2026 at 7:22 PM
Live
Closed
IBB | FBT | |
|---|---|---|
| Last price | $165.27 | $200.59 |
| 1D performance | -1.51% | -1.32% |
| AuM | $8.03 B | $2.30 B |
| E/R | 0.44% | 0.54% |
Characteristics
IBB | FBT | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | iShares | First Trust |
| Benchmark | ICE Biotechnology Index | NYSE Arca Biotechnology Index |
| N° of holdings | 179 | 28 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | February 5, 2001 | June 19, 2006 |
| ESG | No | No |
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Exposure
Countries
IBB
USA
95.97%
Other
4.03%
FBT
USA
95.76%
Other
4.24%
Sectors
IBB
Health Care
85.68%
Other
14.32%
FBT
Health Care
90.59%
Other
9.41%
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Diversification
IBB
Total weight of top 15 holdings out of 15
55.88%
FBT
Total weight of top 15 holdings out of 15
56.66%
Top 15 holdings
Data as of March 31, 2026
IBB
GILEAD SCIENCES
7.75%
AMGEN-T
7.51%
VERTEX PHARMACEUTICALS
7.44%
REGENERON PHARMACEUTICALS
7.21%
ALNYLAM PHARMACEUTICALS
3.99%
INSMED
3.20%
US04016X1019
3.07%
BIOGEN INC
2.46%
NATERA
2.41%
UTD THERAPEUT
2.30%
US07725L1026
1.93%
INCYTE
1.70%
MODERNA INC
1.68%
ILLUMINA
1.68%
REVOLUTION MEDICINES INC
1.54%
FBT
MODERNA INC
5.14%
ALKERMES
4.16%
UTD THERAPEUT
4.15%
GILEAD SCIENCES
4.08%
CORCEPT THERAPEUTICS
3.94%
AXSOME THERA CMN STK
3.91%
AMGEN-T
3.81%
EXELIXIS
3.52%
KRYSTAL BIOTECH INC
3.49%
BIOGEN INC
3.45%
NEUROCRINE BIOSCIENCES
3.44%
REGENERON PHARMACEUTICALS
3.44%
BIOMARIN PHARMACEUTICAL
3.42%
VERTEX PHARMACEUTICALS
3.39%
US04016X1019
3.32%
Frequently asked questions about IBB and FBT
How have the IBB and FBT ETFs performed in 2026?
As of April 27, 2026, IBB is up 0.16% year-to-date (YTD), while FBT has lost -0.95%. That puts IBB better performer ahead so far this year.
Which ETF is attracting more investor money: IBB or FBT?
Year-to-date, the IBB ETF saw -$327M in flows, compared to +$1.07B for FBT.
Which ETF is more volatile: IBB or FBT?
Over the past year, IBB had a volatility of 21.2%, while FBT experienced 21.73%.
Which ETF is bigger: IBB or FBT?
As of April 27, 2026, IBB holds $8.03 B in assets under management (AUM), while FBT manages $2.30 B.
What sectors do the IBB and FBT ETFs invest in?
IBB leans toward sectors like Health Care. Meanwhile, FBT focuses on Health Care.
What are the top holdings of the IBB ETF and FBT ETF?
IBB top holdings include GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS. FBT holds in its top three: MODERNA INC, ALKERMES and UTD THERAPEUT.
Which ETF is more diversified: IBB or FBT?
IBB holds 249 securities with 55.88% of its assets in the top 15. FBT has 30 securities and a top 15 weight of 56.66%.
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