GNOMvsIBBETF Comparison
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Global X Genomics & Biotechnology ETF - USD (GNOM) belongs to the BioTech & Genomics segment. iShares Biotechnology ETF (IBB) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. GNOM is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.44% for IBB. GNOM is up 0.74% year-to-date (YTD) with -$602K in YTD flows. IBB performs worse with 0.69% YTD performance, and -$200M in YTD flows. Run a side-by-side ETF comparison of GNOM and IBB below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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GNOM vs IBB performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | GNOM IBB | +7.67%+5.04% | -7.03%-3.38% | +0.74%+0.69% | +41.51%+37.00% | -6.56%+28.67% | -50.60%+8.66% |
| Flows | GNOM IBB | -$829K+$241M | +$1M-$196M | -$602K-$200M | -$14M+$775M | -$120M-$1.51B | +$1M-$1.91B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | GNOM IBB | +28.47%+22.36% | +27.16%+21.19% | +28.79%+19.80% | +33.22%+22.08% |
| Max drawdown | GNOM IBB | -16.08%-9.27% | -18.16%-9.61% | -46.50%-24.82% | -72.17%-39.75% |
| Max drawdown duration | GNOM IBB | 88d87d | 92d92d | 1075d377d | 1758d1611d |
Trading data
GNOM | IBB | |
Last sale 4/27/2026 at 1:30 PM | $45.43 | $169.02 |
| Previous close 04/24/2026 | $45.97 | $169.78 |
| Consolidated volume 04/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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GNOM | IBB | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/27/2026 at 1:30 PM
Live
Closed
GNOM | IBB | |
|---|---|---|
| Last price | $45.43 | $169.02 |
| 1D performance | -1.17% | -0.45% |
| AuM | $51.60 M | $8.19 B |
| E/R | 0.5% | 0.44% |
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Exposure
Countries
GNOM
USA
87.57%
Other
12.43%
IBB
USA
95.97%
Other
4.03%
Sectors
GNOM
Health Care
88.49%
Other
11.51%
IBB
Health Care
85.68%
Other
14.32%
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Diversification
GNOM
Total weight of top 15 holdings out of 15
66.21%
IBB
Total weight of top 15 holdings out of 15
55.88%
Top 15 holdings
Data as of March 31, 2026
GNOM
MODERNA INC
8.48%
ARROWHEAD PHARMACEUTICALS INC
6.21%
US74006W2070
6.13%
ILLUMINA
5.52%
GUARDANT HEALTH INC
5.18%
VERTEX PHARMACEUTICALS
4.61%
BIOMARIN PHARMACEUTICAL
4.59%
NATERA
4.21%
BIO-TECHNE CORP
3.64%
BIONTECH SE ADR
3.58%
CRISPR THERAPEUTICS
3.08%
BRISTOL-MYERS SQUIBB
3.05%
ALNYLAM PHARMACEUTICALS
2.85%
TWIST BIOSCIENCE CORP
2.54%
ASTRAZENECA
2.53%
IBB
GILEAD SCIENCES
7.75%
AMGEN-T
7.51%
VERTEX PHARMACEUTICALS
7.44%
REGENERON PHARMACEUTICALS
7.21%
ALNYLAM PHARMACEUTICALS
3.99%
INSMED
3.20%
US04016X1019
3.07%
BIOGEN INC
2.46%
NATERA
2.41%
UTD THERAPEUT
2.30%
US07725L1026
1.93%
INCYTE
1.70%
MODERNA INC
1.68%
ILLUMINA
1.68%
REVOLUTION MEDICINES INC
1.54%
Frequently asked questions about GNOM and IBB
How have the GNOM and IBB ETFs performed in 2026?
As of April 24, 2026, GNOM is up 0.74% year-to-date (YTD), while IBB has returned 0.69%. That puts GNOM better performer ahead so far this year.
Which ETF is attracting more investor money: GNOM or IBB?
Year-to-date, the GNOM ETF saw -$602K in flows, compared to -$200M for IBB.
Which ETF is more volatile: GNOM or IBB?
Over the past year, GNOM had a volatility of 27.16%, while IBB experienced 21.19%.
Which ETF is bigger: GNOM or IBB?
As of April 24, 2026, GNOM holds $51.60 M in assets under management (AUM), while IBB manages $8.19 B.
What sectors do the GNOM and IBB ETFs invest in?
GNOM leans toward sectors like Health Care. Meanwhile, IBB focuses on Health Care.
What are the top holdings of the GNOM ETF and IBB ETF?
GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. IBB holds in its top three: GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS.
Which ETF is more diversified: GNOM or IBB?
GNOM holds 47 securities with 66.21% of its assets in the top 15. IBB has 249 securities and a top 15 weight of 55.88%.
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Latest news about GNOM & IBB
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Biotech ETFs – Investing in Health Innovation
July 21, 2022
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Biotech ETFs – Investing in Health Innovation
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