FBTvsIBBETF Comparison
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First Trust NYSE Arca Biotechnology Index Fund ETF (FBT) and iShares Biotechnology ETF (IBB) belong to the same industry segment: US Health Care. FBT's top 1 sector exposures are Healthcare. In contrast, IBB's top sector exposures are Healthcare, Non-Corporate and Non-Energy Materials. FBT is more expensive with a Total Expense Ratio (TER) of 0.54%, versus 0.44% for IBB. FBT is up 28.39% year-to-date (YTD) with +$964M in YTD flows. IBB performs worse with 19.83% YTD performance, and +$454M in YTD flows. Run a side-by-side ETF comparison of FBT and IBB below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FBT vs IBB performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/14/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FBT IBB | +3.54%+0.12% | +16.13%+17.42% | +28.39%+19.83% | +50.51%+44.00% | +74.11%+60.97% | +56.86%+19.21% |
| Flows | FBT IBB | +$13M+$280M | -$159M+$865M | +$964M+$454M | +$1.04B+$1.92B | +$626M-$499M | +$283M-$1.22B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FBT IBB | +22.16%+24.19% | +21.76%+21.71% | +21.12%+21.09% | +22.21%+22.47% |
| Max drawdown | FBT IBB | -4.50%-6.84% | -14.27%-9.61% | -19.92%-24.82% | -29.49%-38.96% |
| Max drawdown duration | FBT IBB | 18d27d | 126d151d | 237d377d | 1138d1523d |
Trading data
FBT | IBB | |
Last sale 9/16/2026 at 6:00 PM | $266.59 | $203.37 |
| Previous close 09/15/2026 | $262.99 | $202.00 |
| Consolidated volume 09/15/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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FBT | IBB | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/16/2026 at 6:00 PM
Live
Closed
FBT | IBB | |
|---|---|---|
| Last price | $266.59 | $203.37 |
| 1D performance | +1.37% | +0.68% |
| AuM | $2.88 B | $10.39 B |
| E/R | 0.54% | 0.44% |
Characteristics
FBT | IBB | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | iShares |
| Benchmark | NYSE Arca Biotechnology Index | ICE Biotechnology Index |
| N° of holdings | 30 | 240 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 19, 2006 | February 5, 2001 |
| ESG | No | No |
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Exposure
Countries
FBT
USA
82.19%
Other
17.81%
IBB
USA
86.04%
Other
13.96%
Sectors
FBT
Healthcare
99.86%
Other
0.14%
IBB
Healthcare
99.83%
Other
0.17%
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Diversification
FBT
Total weight of top 15 holdings out of 15
55.87%
IBB
Total weight of top 15 holdings out of 15
54.48%
Top 15 holdings
Data as of July 31, 2026
FBT
Halozyme Therapeutics, Inc.
4.31%
Corcept Therapeutics, Inc.
4.08%
Repligen Corp.
3.87%
Regeneron Pharmaceuticals, Inc.
3.85%
BeOne Medicines Ltd.
3.83%
BioNTech SE
3.75%
Natera, Inc.
3.73%
Amgen, Inc.
3.70%
argenx SE
3.66%
NeoGenomics, Inc.
3.63%
Genmab A/S
3.57%
BioMarin Pharmaceutical, Inc.
3.55%
Illumina, Inc.
3.47%
Vertex Pharmaceuticals, Inc.
3.45%
Gilead Sciences, Inc.
3.42%
IBB
Amgen, Inc.
8.42%
Vertex Pharmaceuticals, Inc.
7.87%
Gilead Sciences, Inc.
7.14%
Regeneron Pharmaceuticals, Inc.
5.84%
argenx SE
3.55%
Natera, Inc.
2.88%
Revolution Medicines, Inc.
2.87%
Illumina, Inc.
2.42%
Biogen, Inc.
2.38%
Alnylam Pharmaceuticals, Inc.
2.14%
BeOne Medicines Ltd.
2.01%
Incyte Corp.
1.91%
Insmed, Inc.
1.71%
United Therapeutics Corp.
1.69%
Moderna, Inc.
1.65%
Frequently asked questions about FBT and IBB
How have the FBT and IBB ETFs performed in 2026?
As of September 14, 2026, FBT is up 28.39% year-to-date (YTD), while IBB has returned 19.83%. That puts FBT better performer ahead so far this year.
Which ETF is attracting more investor money: FBT or IBB?
Year-to-date, the FBT ETF saw +$964M in flows, compared to +$454M for IBB.
Which ETF is more volatile: FBT or IBB?
Over the past year, FBT had a volatility of 21.76%, while IBB experienced 21.71%.
Which ETF is bigger: FBT or IBB?
As of September 14, 2026, FBT holds $2.88 B in assets under management (AUM), while IBB manages $10.39 B.
What sectors do the FBT and IBB ETFs invest in?
FBT leans toward sectors like Healthcare. Meanwhile, IBB focuses on Healthcare.
What are the top holdings of the FBT ETF and IBB ETF?
FBT top holdings include Halozyme Therapeutics, Inc., Corcept Therapeutics, Inc. and Repligen Corp.. IBB holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..
Which ETF is more diversified: FBT or IBB?
FBT holds 30 securities with 55.87% of its assets in the top 15. IBB has 241 securities and a top 15 weight of 54.48%.
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