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EKGvsIBBETF Comparison

ETF 1
EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of
Healthcare Technology
-0%
VS
ETF 2
IBB

iShares Biotechnology ETF

This fund is part of
US Health Care
+0.07%

First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) belongs to the Healthcare Technology segment. iShares Biotechnology ETF (IBB) is part of the US Health Care segment. EKG's top 1 sector exposures are Healthcare. In contrast, IBB's top sector exposures are Healthcare, Non-Corporate and Non-Energy Materials. EKG is more expensive with a Total Expense Ratio (TER) of 0.65%, versus 0.44% for IBB. EKG is up 17.24% year-to-date (YTD) with +$963K in YTD flows. IBB performs better with 20.05% YTD performance, and +$444M in YTD flows. Run a side-by-side ETF comparison of EKG and IBB below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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EKG vs IBB performance and flow charts

Performance

0.02.04.06.08.0%Aug 17Aug 24Aug 31Sep 8Sep 15

Cumulative Flows

-50 M0 M50 M100 M150 M200 M250 M300 MAug 17Aug 24Aug 31Sep 8Sep 15

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Historic performance and flows
Data as of 09/15/2026
1M3MYTD1Y3Y5Y
Perf.
EKG
IBB
+6.16%+0.30%
+25.66%+18.09%
+17.24%+20.05%
+28.39%+43.89%
+49.43%+63.04%
n/a+18.88%
Flows
EKG
IBB
-+$270M
+$963K+$777M
+$963K+$444M
+$963K+$1.91B
+$2M-$503M
--$1.18B
Volatility and drawdown
3M1Y3Y5Y
Volatility
EKG
IBB
+26.58%+24.16%
+23.58%+21.71%
+23.88%+21.08%
n/a+22.47%
Max drawdown
EKG
IBB
-7.45%-6.84%
-22.11%-9.61%
-24.32%-24.82%
n/a-38.96%
Max drawdown duration
EKG
IBB
28d28d
208d151d
264d377d
n/a1523d
Trading data

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EKG
IBB
Last sale
9/17/2026 at 1:30 PM
$22.88
$207.07
Previous close
09/16/2026
$22.32
$202.40
Consolidated volume
09/16/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of August 31, 2026
1-year trailing difference

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EKG
IBB
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 9/17/2026 at 1:30 PM
Live
Closed
EKG
IBB
Last price
$22.88
$207.07
1D performance
+2.52%
+2.31%
AuM$4.46 M$10.40 B
E/R0.65%0.44%
Characteristics
EKG
IBB
Management strategyPassivePassive
ProviderFirst TrustiShares
BenchmarkNasdaq Lux Health Tech IndexICE Biotechnology Index
N° of holdings37240
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateMarch 22, 2022February 5, 2001
ESGNoNo
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Exposure

Countries

EKG
USA
95.72%
Other
4.28%
IBB
USA
86.04%
Other
13.96%

Sectors

EKG
Healthcare
98.67%
Other
1.33%
IBB
Healthcare
99.83%
Other
0.17%
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Diversification

EKG

Total weight of top 15 holdings out of 15

74.55%
IBB

Total weight of top 15 holdings out of 15

54.48%

Top 15 holdings

Data as of July 31, 2026
EKG
IQVIA Holdings, Inc.
9.37%
Veeva Systems, Inc.
9.01%
DexCom, Inc.
8.04%
Guardant Health, Inc.
5.85%
ResMed, Inc.
5.83%
Illumina, Inc.
5.19%
Natera, Inc.
5.11%
Intuitive Surgical, Inc.
4.87%
Oscar Health, Inc.
3.90%
Tempus AI, Inc.
3.64%
QIAGEN NV
2.95%
Globus Medical, Inc.
2.94%
Align Technology, Inc.
2.74%
10X Genomics, Inc.
2.57%
Hims & Hers Health, Inc.
2.54%
IBB
Amgen, Inc.
8.42%
Vertex Pharmaceuticals, Inc.
7.87%
Gilead Sciences, Inc.
7.14%
Regeneron Pharmaceuticals, Inc.
5.84%
argenx SE
3.55%
Natera, Inc.
2.88%
Revolution Medicines, Inc.
2.87%
Illumina, Inc.
2.42%
Biogen, Inc.
2.38%
Alnylam Pharmaceuticals, Inc.
2.14%
BeOne Medicines Ltd.
2.01%
Incyte Corp.
1.91%
Insmed, Inc.
1.71%
United Therapeutics Corp.
1.69%
Moderna, Inc.
1.65%
Frequently asked questions about EKG and IBB

How have the EKG and IBB ETFs performed in 2026?

As of September 15, 2026, EKG is up 17.24% year-to-date (YTD), while IBB has returned 20.05%. That puts IBB better performer ahead so far this year.

Which ETF is attracting more investor money: EKG or IBB?

Year-to-date, the EKG ETF saw +$963K in flows, compared to +$444M for IBB.

Which ETF is more volatile: EKG or IBB?

Over the past year, EKG had a volatility of 23.58%, while IBB experienced 21.71%.

Which ETF is bigger: EKG or IBB?

As of September 15, 2026, EKG holds $4.46 M in assets under management (AUM), while IBB manages $10.40 B.

What sectors do the EKG and IBB ETFs invest in?

EKG leans toward sectors like Healthcare. Meanwhile, IBB focuses on Healthcare.

What are the top holdings of the EKG ETF and IBB ETF?

EKG top holdings include IQVIA Holdings, Inc., Veeva Systems, Inc. and DexCom, Inc.. IBB holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..

Which ETF is more diversified: EKG or IBB?

EKG holds 37 securities with 74.55% of its assets in the top 15. IBB has 241 securities and a top 15 weight of 54.48%.

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