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CANCvsSBIOETF Comparison

ETF 1
CANC

Tema Oncology ETF

This fund is part of
Tomorrow's Treatments
-0.34%
VS
ETF 2
SBIO

ALPS Medical Breakthroughs ETF

This fund is part of
Tomorrow's Treatments
-0.34%

Tema Oncology ETF (CANC) and ALPS Medical Breakthroughs ETF (SBIO) belong to the same industry segment: Tomorrow's Treatments. CANC's top 3 sector exposures are and Health Care. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.5% for SBIO. CANC is up 10.62% year-to-date (YTD) with +$50M in YTD flows. SBIO performs worse with 6.34% YTD performance, and +$19M in YTD flows. Run a side-by-side ETF comparison of CANC and SBIO below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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CANC vs SBIO performance and flow charts

Performance

05101520%Mar 24Mar 31Apr 8Apr 15Apr 22

Cumulative Flows

-5 M0 M5 M10 MMar 24Mar 31Apr 8Apr 15Apr 22

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 04/24/2026
1M3MYTD1Y3Y5Y
Perf.
CANC
SBIO
+10.08%+12.66%
+5.34%+3.68%
+10.62%+6.34%
+55.67%+90.50%
n/a+86.93%
n/a+11.39%
Flows
CANC
SBIO
+$5M+$13M
+$29M+$16M
+$50M+$19M
+$70M+$13M
--$5M
--$60M
Volatility and drawdown
3M1Y3Y5Y
Volatility
CANC
SBIO
+23.62%+33.23%
+23.46%+29.78%
n/a+29.96%
n/a+33.52%
Max drawdown
CANC
SBIO
-7.99%-9.27%
-10.53%-11.04%
n/a-42.12%
n/a-53.58%
Max drawdown duration
CANC
SBIO
43d64d
32d75d
n/a331d
n/a1672d
Trading data

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CANC
SBIO
Last sale
4/27/2026 at 1:30 PM
$37.78
$54.26
Previous close
04/24/2026
$38.36
$54.41
Consolidated volume
04/24/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of March 31, 2026
1-year trailing difference

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CANC
is actively managed and doesn’t replicate an index

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CANC
SBIO
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 4/27/2026 at 1:30 PM
Live
Closed
CANC
SBIO
Last price
$37.78
$54.26
1D performance
-1.52%
-0.28%
AuM$179.70 M$153.60 M
E/R0.99%0.5%
Characteristics
CANC
SBIO
Management strategyActivePassive
ProviderTemaALPS
Benchmark-S-Network Medical Breakthroughs Index
N° of holdings44-
Asset class-Equities
Trailing 12m distribution yield
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Inception dateAugust 15, 2023December 30, 2014
ESGNoNo
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Exposure

Countries

CANC
USA
85.51%
Other
14.49%
SBIO
Data will be available soon

Sectors

CANC
Health Care
78.17%
Other
21.83%
SBIO
Data will be available soon
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Diversification

CANC

Total weight of top 15 holdings out of 15

56.1%
SBIO
Data will be available soon

Top 15 holdings

Data as of March 31, 2026
CANC
REVOLUTION MEDICINES INC
4.95%
ASTRAZENECA
4.60%
NOVARTIS
4.45%
US7711951043
4.26%
LILLY
4.20%
BRIDGEBIO PHARMA
3.94%
COGENT BIOSCIENCES
3.88%
BRISTOL-MYERS SQUIBB
3.74%
MERCK & CO INC
3.62%
IMMUNOME
3.30%
JOHNSON&JOHNSON
3.23%
NUVALENT
3.20%
CELCUITY INC
3.07%
US3723032062
2.95%
ABBVIE
2.71%
SBIO
Data will be available soon
Frequently asked questions about CANC and SBIO

How have the CANC and SBIO ETFs performed in 2026?

As of April 24, 2026, CANC is up 10.62% year-to-date (YTD), while SBIO has returned 6.34%. That puts CANC better performer ahead so far this year.

Which ETF is attracting more investor money: CANC or SBIO?

Year-to-date, the CANC ETF saw +$50M in flows, compared to +$19M for SBIO.

Which ETF is more volatile: CANC or SBIO?

Over the past year, CANC had a volatility of 23.46%, while SBIO experienced 29.78%.

Which ETF is bigger: CANC or SBIO?

As of April 24, 2026, CANC holds $179.70 M in assets under management (AUM), while SBIO manages $153.60 M.

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Latest news about CANC & SBIO
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