PPHvsMEDXETF Comparison
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VanEck Pharmaceutical ETF (PPH) belongs to the Uncategorized Equities segment. Horizon Kinetics Medical ETF (MEDX) is part of the Tomorrow's Treatments segment. Both ETFs have the same top 3 sector exposures: and Healthcare. PPH is less expensive with a Total Expense Ratio (TER) of 0.36%, versus 0.85% for MEDX. PPH is up 8.75% year-to-date (YTD) with -$377M in YTD flows. MEDX performs worse with 6.77% YTD performance, and -$3M in YTD flows. Run a side-by-side ETF comparison of PPH and MEDX below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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PPH vs MEDX performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | PPH MEDX | +5.25%+1.04% | +10.99%+10.61% | +8.75%+6.77% | +26.11%+27.70% | +45.51%+26.13% | +65.20%n/a |
| Flows | PPH MEDX | +$15M-$883K | -$106M-$2M | -$377M-$3M | +$257M-$3M | +$353M-$4M | +$396M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | PPH MEDX | +20.60%+20.98% | +18.27%+18.56% | +15.75%+17.30% | +15.33%n/a |
| Max drawdown | PPH MEDX | -4.39%-7.93% | -10.78%-10.65% | -17.98%-23.05% | -20.19%n/a |
| Max drawdown duration | PPH MEDX | 17d17d | 122d115d | 434d393d | 484dn/a |
Trading data
PPH | MEDX | |
Last sale 7/27/2026 at 1:30 PM | $111.31 | $35.58 |
| Previous close 07/24/2026 | $110.63 | $35.49 |
| Consolidated volume 07/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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MEDX
is actively managed and doesn’t replicate an indexPPH | MEDX | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/27/2026 at 1:30 PM
Live
Closed
PPH | MEDX | |
|---|---|---|
| Last price | $111.31 | $35.58 |
| 1D performance | +0.61% | +0.25% |
| AuM | $960.98 M | $17.57 M |
| E/R | 0.36% | 0.85% |
Characteristics
PPH | MEDX | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | VanEck | Horizon Kinetics LLC |
| Benchmark | MVIS US Listed Pharmaceutical 25 Index | - |
| N° of holdings | 25 | 30 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 20, 2011 | January 27, 2023 |
| ESG | No | No |
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Exposure
Countries
PPH
USA
61.03%
United Kingdom
11.84%
Switzerland
10.63%
Other
16.49%
MEDX
USA
68.17%
Switzerland
10.22%
United Kingdom
8.49%
Other
13.12%
Sectors
PPH
Healthcare
100%
MEDX
Healthcare
92.67%
Other
7.33%
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Diversification
PPH
Total weight of top 15 holdings out of 15
90.85%
MEDX
Total weight of top 15 holdings out of 15
81.88%
Top 15 holdings
Data as of June 30, 2026
PPH
Eli Lilly & Co.
20.64%
Novartis AG
10.63%
Merck & Co., Inc.
9.86%
Novo Nordisk A/S
5.38%
AbbVie, Inc.
4.60%
Pfizer Inc.
4.54%
Bristol Myers Squibb Co.
4.52%
GSK Plc
4.43%
Johnson & Johnson
4.41%
AstraZeneca PLC
4.34%
McKesson Corp.
4.06%
Sanofi
4.06%
Cencora, Inc.
3.32%
Haleon Plc
3.08%
Teva Pharmaceutical Industries Ltd.
2.99%
MEDX
Eli Lilly & Co.
18.51%
AbbVie, Inc.
8.87%
Novartis AG
6.80%
Alkermes Plc
5.79%
Johnson & Johnson
5.58%
AstraZeneca PLC
4.93%
Ionis Pharmaceuticals, Inc.
4.62%
Bristol Myers Squibb Co.
4.40%
Merck & Co., Inc.
3.94%
Amgen, Inc.
3.86%
Alnylam Pharmaceuticals, Inc.
3.30%
Biogen, Inc.
3.07%
Pfizer Inc.
2.87%
GSK Plc
2.70%
CRISPR Therapeutics AG
2.64%
Frequently asked questions about PPH and MEDX
How have the PPH and MEDX ETFs performed in 2026?
As of July 24, 2026, PPH is up 8.75% year-to-date (YTD), while MEDX has returned 6.77%. That puts PPH better performer ahead so far this year.
Which ETF is attracting more investor money: PPH or MEDX?
Year-to-date, the PPH ETF saw -$377M in flows, compared to -$3M for MEDX.
Which ETF is more volatile: PPH or MEDX?
Over the past year, PPH had a volatility of 18.27%, while MEDX experienced 18.56%.
Which ETF is bigger: PPH or MEDX?
As of July 24, 2026, PPH holds $960.98 M in assets under management (AUM), while MEDX manages $17.57 M.
What sectors do the PPH and MEDX ETFs invest in?
PPH leans toward sectors like Healthcare. Meanwhile, MEDX focuses on Healthcare.
What are the top holdings of the PPH ETF and MEDX ETF?
PPH top holdings include Eli Lilly & Co., Novartis AG and Merck & Co., Inc.. MEDX holds in its top three: Eli Lilly & Co., AbbVie, Inc. and Novartis AG.
Which ETF is more diversified: PPH or MEDX?
PPH holds 25 securities with 90.85% of its assets in the top 15. MEDX has 30 securities and a top 15 weight of 81.88%.
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