HRTSvsIHEETF Comparison
VS
Tema GLP-1, Obesity & Cardiometabolic ETF (HRTS) belongs to the Tomorrow's Treatments segment. iShares U.S. Pharmaceuticals ETF (IHE) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. HRTS is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.38% for IHE. HRTS is down -7.09% year-to-date (YTD) with -$2M in YTD flows. IHE performs better with 0.36% YTD performance, and +$68M in YTD flows. Run a side-by-side ETF comparison of HRTS and IHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
Find out how industry players manage ETF portfolios. Discover our library of Model portfolios
HRTS vs IHE performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/29/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | HRTS IHE | +0.22%+0.73% | -7.83%-1.40% | -7.09%+0.36% | +15.13%+27.46% | n/a+46.45% | n/a+54.17% |
| Flows | HRTS IHE | -$1M-$61M | -$4M-$33M | -$2M+$68M | -$12M+$199M | -+$299M | -+$332M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | HRTS IHE | +16.39%+18.53% | +16.33%+17.93% | n/a+16.13% | n/a+16.00% |
| Max drawdown | HRTS IHE | -9.68%-8.48% | -10.68%-9.18% | n/a-16.04% | n/a-16.12% |
| Max drawdown duration | HRTS IHE | 59d59d | 112d82d | n/a210d | n/a669d |
Trading data
HRTS | IHE | |
Last sale 4/29/2026 at 6:04 PM | $32.74 | $87.54 |
| Previous close 04/29/2026 | $33.15 | $84.82 |
| Consolidated volume 04/29/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
Create an account to view replication metrics
Join for free
HRTS
is actively managed and doesn’t replicate an indexHRTS | IHE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
Advertisement
Main metrics
Last update 4/29/2026 at 6:04 PM
Live
Closed
HRTS | IHE | |
|---|---|---|
| Last price | $32.74 | $87.54 |
| 1D performance | -1.22% | +3.21% |
| AuM | $48.91 M | $915.85 M |
| E/R | 0.99% | 0.38% |
Advertisement
Exposure
Countries
HRTS
USA
82.47%
Other
17.53%
IHE
USA
90.65%
Other
9.35%
Sectors
HRTS
Health Care
87.86%
Other
12.14%
IHE
Health Care
95.58%
Other
4.42%
Diversification
HRTS
Total weight of top 15 holdings out of 15
61.52%
IHE
Total weight of top 15 holdings out of 15
84.72%
Top 15 holdings
Data as of March 31, 2026
HRTS
LILLY
9.70%
JOHNSON&JOHNSON
4.97%
US7711951043
4.94%
ASTRAZENECA
4.91%
MERCK & CO INC
4.46%
THERMO FISHER SCIENTIFIC
4.06%
UNITEDHEALTH GRP
3.79%
GILEAD SCIENCES
3.66%
NOVARTIS
3.52%
VERTEX PHARMACEUTICALS
3.30%
ABBOTT LABS
3.26%
ABBVIE
3.00%
BRIDGEBIO PHARMA
2.85%
DANAHER
2.81%
BRISTOL-MYERS SQUIBB
2.29%
IHE
JOHNSON&JOHNSON
23.02%
LILLY
21.05%
MERCK & CO INC
4.74%
PFIZER
4.71%
ROYALTY PHARMA
4.70%
BRISTOL-MYERS SQUIBB
4.63%
ZOETIS INC
4.52%
VIATRIS INC
4.35%
ELANCO ANIMAL HEALTH INC
3.32%
JAZZ PHARMACEUTICALS
3.21%
AXSOME THERA CMN STK
2.00%
TERNS PHARMACEUTICALS
1.27%
LIGAND PHARMACEUTICALS
1.10%
US45579U1097
1.06%
CORCEPT THERAPEUTICS
1.05%
Frequently asked questions about HRTS and IHE
How have the HRTS and IHE ETFs performed in 2026?
As of April 29, 2026, HRTS is down -7.09% year-to-date (YTD), while IHE has returned 0.36%. That puts IHE better performer ahead so far this year.
Which ETF is attracting more investor money: HRTS or IHE?
Year-to-date, the HRTS ETF saw -$2M in flows, compared to +$68M for IHE.
Which ETF is more volatile: HRTS or IHE?
Over the past year, HRTS had a volatility of 16.33%, while IHE experienced 17.93%.
Which ETF is bigger: HRTS or IHE?
As of April 29, 2026, HRTS holds $48.91 M in assets under management (AUM), while IHE manages $915.85 M.
What sectors do the HRTS and IHE ETFs invest in?
HRTS leans toward sectors like Health Care. Meanwhile, IHE focuses on Health Care.
What are the top holdings of the HRTS ETF and IHE ETF?
HRTS top holdings include LILLY, JOHNSON&JOHNSON and US7711951043. IHE holds in its top three: JOHNSON&JOHNSON, LILLY and MERCK & CO INC.
Which ETF is more diversified: HRTS or IHE?
HRTS holds 44 securities with 61.52% of its assets in the top 15. IHE has 57 securities and a top 15 weight of 84.72%.
Advertisement
Latest news about HRTS & IHE
Obesity and Weight-Loss Drugs: A New Thematic ETF Segment?
April 18, 2024
HRTS
Analyzing the Potential ETF Winners & Losers from The Weight-Loss Drug Craze
November 20, 2023
IHE
Healthcare Stocks Rebound
August 14, 2023
IHE
Advertisement
Health is Wealth: A look at the Healthcare Sector
January 24, 2023
IHE
Health is Wealth: A look at the Healthcare Sector
January 24, 2023
IHE
Advertisement
