XPHvsXHEETF Comparison
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State Street SPDR S&P Pharmaceuticals ETF (XPH) and State Street SPDR S&P Health Care Equipment ETF (XHE) belong to the same industry segment: US Health Care. XPH's top 1 sector exposures are Healthcare. In contrast, XHE's top sector exposures are Healthcare and Finance. Both XPH and XHE have the same Total Expense Ratio (TER) of 0.35%. XPH is up 14.29% year-to-date (YTD) with +$186M in YTD flows. XHE performs worse with 5.71% YTD performance, and -$9M in YTD flows. Run a side-by-side ETF comparison of XPH and XHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XPH vs XHE performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XPH XHE | -4.31%+1.69% | -6.56%+6.51% | +14.29%+5.71% | +30.94%+13.97% | +86.70%+39.19% | +44.35%-24.85% |
| Flows | XPH XHE | -$80M-$40M | +$11M-$10M | +$186M-$9M | +$206M-$12M | +$160M-$223M | +$157M-$399M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XPH XHE | +22.82%+20.36% | +23.36%+22.70% | +20.82%+21.88% | +21.10%+24.86% |
| Max drawdown | XPH XHE | -16.58%-9.09% | -16.58%-18.20% | -23.45%-24.35% | -30.87%-49.37% |
| Max drawdown duration | XPH XHE | 69d69d | 69d207d | 322d565d | 1452d1819d |
Trading data
XPH | XHE | |
Last sale 10/27/2026 at 7:59 PM | $63.96 | $93.12 |
| Previous close 10/27/2026 | $62.90 | $93.09 |
| Consolidated volume 10/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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XPH | XHE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 10/27/2026 at 7:59 PM
Live
Closed
XPH | XHE | |
|---|---|---|
| Last price | $63.96 | $93.12 |
| 1D performance | +1.69% | +0.03% |
| AuM | $447.54 M | $153.71 M |
| E/R | 0.35% | 0.35% |
Characteristics
XPH | XHE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | State Street Investment Management | State Street Investment Management |
| Benchmark | S&P Pharmaceuticals Select Industry Index | S&P Health Care Equipment Select Industry Index |
| N° of holdings | 62 | 67 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 19, 2006 | January 26, 2011 |
| ESG | No | No |
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Exposure
Countries
XPH
USA
89.77%
Other
10.23%
XHE
USA
93.57%
Other
6.43%
Sectors
XPH
Healthcare
93.27%
Other
6.73%
XHE
Healthcare
97.47%
Other
2.53%
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Diversification
XPH
Total weight of top 15 holdings out of 15
34.13%
XHE
Total weight of top 15 holdings out of 15
30.96%
Top 15 holdings
Data as of August 31, 2026
XPH
Amylyx Pharmaceuticals, Inc.
3.65%
Crinetics Pharmaceuticals, Inc.
3.60%
MBX Biosciences, Inc.
2.89%
Omeros Corp.
2.68%
Enliven Therapeutics, Inc.
2.28%
Nuvation Bio, Inc.
2.12%
Corcept Therapeutics, Inc.
2.11%
Eton Pharmaceuticals, Inc.
2.08%
Perrigo Co. Plc
1.91%
Edgewise Therapeutics, Inc.
1.85%
Nektar Therapeutics
1.83%
Merck & Co., Inc.
1.81%
Trevi Therapeutics, Inc.
1.80%
Tarsus Pharmaceuticals, Inc.
1.76%
Bristol Myers Squibb Co.
1.75%
XHE
AtriCure, Inc.
2.59%
Strive, Inc. (United States)
2.47%
Inspire Medical Systems, Inc.
2.19%
Glaukos Corp.
2.16%
Butterfly Network, Inc.
2.15%
CONMED Corp.
2.02%
Integer Holdings Corp.
2.02%
Tandem Diabetes Care, Inc.
2.00%
Merit Medical Systems, Inc.
1.99%
Artivion, Inc.
1.94%
Haemonetics Corp.
1.93%
UFP Technologies, Inc.
1.89%
Baxter International, Inc.
1.88%
Becton, Dickinson & Co.
1.87%
Neogen Corp.
1.86%
Frequently asked questions about XPH and XHE
How have the XPH and XHE ETFs performed in 2026?
As of October 27, 2026, XPH is up 14.29% year-to-date (YTD), while XHE has returned 5.71%. That puts XPH better performer ahead so far this year.
Which ETF is attracting more investor money: XPH or XHE?
Year-to-date, the XPH ETF saw +$186M in flows, compared to -$9M for XHE.
Which ETF is more volatile: XPH or XHE?
Over the past year, XPH had a volatility of 23.36%, while XHE experienced 22.7%.
Which ETF is bigger: XPH or XHE?
As of October 27, 2026, XPH holds $447.54 M in assets under management (AUM), while XHE manages $153.71 M.
What sectors do the XPH and XHE ETFs invest in?
XPH leans toward sectors like Healthcare. Meanwhile, XHE focuses on Healthcare.
What are the top holdings of the XPH ETF and XHE ETF?
XPH top holdings include Amylyx Pharmaceuticals, Inc., Crinetics Pharmaceuticals, Inc. and MBX Biosciences, Inc.. XHE holds in its top three: AtriCure, Inc., Strive, Inc. (United States) and Inspire Medical Systems, Inc..
Which ETF is more diversified: XPH or XHE?
XPH holds 62 securities with 34.13% of its assets in the top 15. XHE has 67 securities and a top 15 weight of 30.96%.
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