XPHvsXHEETF Comparison
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State Street SPDR S&P Pharmaceuticals ETF (XPH) and State Street SPDR S&P Health Care Equipment ETF (XHE) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. Both XPH and XHE have the same Total Expense Ratio (TER) of 0.35%. XPH is up 2.61% year-to-date (YTD) with +$116M in YTD flows. XHE performs worse with -6.1% YTD performance, and -$6M in YTD flows. Run a side-by-side ETF comparison of XPH and XHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XPH vs XHE performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XPH XHE | +9.68%+4.44% | +2.44%-6.33% | +2.61%-6.10% | +44.99%+4.10% | +40.83%-16.38% | +22.16%-34.81% |
| Flows | XPH XHE | +$25M+$345K | +$82M-$4M | +$116M-$6M | +$141M-$35M | +$48M-$282M | +$64M-$404M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XPH XHE | +24.78%+23.06% | +21.12%+21.27% | +19.49%+21.32% | +20.45%+24.31% |
| Max drawdown | XPH XHE | -11.78%-14.31% | -11.78%-18.20% | -23.45%-32.60% | -31.59%-49.90% |
| Max drawdown duration | XPH XHE | 50d57d | 50d106d | 322d1096d | 1566d1695d |
Trading data
XPH | XHE | |
Last sale 4/24/2026 at 1:30 PM | $57.40 | $82.71 |
| Previous close 04/23/2026 | $57.20 | $82.26 |
| Consolidated volume 04/23/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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XPH | XHE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/24/2026 at 1:30 PM
Live
Closed
XPH | XHE | |
|---|---|---|
| Last price | $57.40 | $82.71 |
| 1D performance | +0.35% | +0.55% |
| AuM | $353.54 M | $138.61 M |
| E/R | 0.35% | 0.35% |
Characteristics
XPH | XHE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | State Street Investment Management | State Street Investment Management |
| Benchmark | S&P Pharmaceuticals Select Industry Index | S&P Health Care Equipment Select Industry Index |
| N° of holdings | 48 | 61 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 19, 2006 | January 26, 2011 |
| ESG | No | No |
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Exposure
Countries
XPH
USA
87.77%
Other
12.23%
XHE
USA
92.19%
Other
7.81%
Sectors
XPH
Health Care
82.36%
Other
17.64%
XHE
Health Care
89.87%
Other
10.13%
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Diversification
XPH
Total weight of top 15 holdings out of 15
30.65%
XHE
Total weight of top 15 holdings out of 15
26.74%
Top 15 holdings
Data as of March 31, 2026
XPH
US29337E1029
2.45%
CORCEPT THERAPEUTICS
2.29%
TERNS PHARMACEUTICALS
2.16%
PERRIGO CO PLC
2.10%
AXSOME THERA CMN STK
2.03%
INNOVIVA INC
1.99%
MERCK & CO INC
1.98%
PFIZER
1.97%
ROYALTY PHARMA
1.97%
ELANCO ANIMAL HEALTH INC
1.96%
JAZZ PHARMACEUTICALS
1.96%
ESPERION THERAPEUTICS
1.95%
EDGEWISE THERAPEUTICS
1.95%
US55287L1017
1.95%
BRISTOL-MYERS SQUIBB
1.94%
XHE
TELEFLEX
1.86%
STAAR SURGICAL
1.84%
BUTTERFLY NETWORK INC
1.84%
US58507V1070
1.83%
GLAUKOS
1.82%
INTEGER HOLDINGS
1.79%
AXOGEN
1.79%
LIVANOVA
1.78%
MASIMO
1.76%
LEMAITRE VASCULAR
1.75%
ARTIVION INC
1.75%
HOLOGIC
1.74%
STERIS
1.74%
GLOBUS MEDICAL
1.72%
IRHYTHM TECHNOLOGIES
1.72%
Frequently asked questions about XPH and XHE
How have the XPH and XHE ETFs performed in 2026?
As of April 24, 2026, XPH is up 2.61% year-to-date (YTD), while XHE has lost -6.1%. That puts XPH better performer ahead so far this year.
Which ETF is attracting more investor money: XPH or XHE?
Year-to-date, the XPH ETF saw +$116M in flows, compared to -$6M for XHE.
Which ETF is more volatile: XPH or XHE?
Over the past year, XPH had a volatility of 21.12%, while XHE experienced 21.27%.
Which ETF is bigger: XPH or XHE?
As of April 24, 2026, XPH holds $353.54 M in assets under management (AUM), while XHE manages $138.61 M.
What sectors do the XPH and XHE ETFs invest in?
XPH leans toward sectors like Health Care. Meanwhile, XHE focuses on Health Care.
What are the top holdings of the XPH ETF and XHE ETF?
XPH top holdings include US29337E1029, CORCEPT THERAPEUTICS and TERNS PHARMACEUTICALS. XHE holds in its top three: TELEFLEX, STAAR SURGICAL and BUTTERFLY NETWORK INC.
Which ETF is more diversified: XPH or XHE?
XPH holds 57 securities with 30.65% of its assets in the top 15. XHE has 67 securities and a top 15 weight of 26.74%.
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