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XPHvsXHEETF Comparison

ETF 1
XPH

SPDR S&P Pharmaceuticals ETF

This fund is part of
US Health Care
-0.31%
Full XPH fund page
VS
ETF 2
XHE

SPDR S&P Health Care Equipment ETF

This fund is part of
US Health Care
-0.31%
Full XHE fund page

SPDR S&P Pharmaceuticals ETF (XPH) and SPDR S&P Health Care Equipment ETF (XHE) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. Both XPH and XHE have the same Total Expense Ratio (TER) of 0.35%. XPH is down -1.12% year-to-date (YTD) with +$88M in YTD flows. XHE performs worse with -6.79% YTD performance, and -$4M in YTD flows. Run a side-by-side ETF comparison of XPH and XHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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XPH vs XHE performance and flow charts

Performance

-6.0-4.0-2.00.02.04.0%Feb 11Feb 19Feb 26Mar 5

Cumulative Flows

05,000,00010,000,00015,000,000Feb 11Feb 19Feb 26Mar 5

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Historic performance and flows
Data as of 03/11/2026
1M3MYTD1Y3Y5Y
Perf.
XPH
XHE
-3.45%-4.63%
-1.36%-8.38%
-1.12%-6.79%
+29.22%-1.88%
+42.98%-7.27%
+9.16%-31.62%
Flows
XPH
XHE
+$12M-
+$95M-$7M
+$88M-$4M
+$111M-$44M
+$48M-$295M
+$36M-$430M
Volatility and drawdown
3M1Y3Y5Y
Volatility
XPH
XHE
+20.33%+18.94%
+23.08%+23.53%
+19.01%+21.07%
+20.26%+24.17%
Max drawdown
XPH
XHE
-5.97%-12.38%
-17.10%-14.34%
-23.45%-32.63%
-33.10%-49.90%
Max drawdown duration
XPH
XHE
14d62d
140d241d
322d1053d
1706d1651d
Trading data

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XPH
XHE
Last sale
3/12/2026 at 1:34 PM
$54.05
$82.04
Previous close
03/11/2026
$55.49
$81.73
Consolidated volume
03/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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XPH
XHE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/12/2026 at 1:34 PM
Live
Closed
XPH
XHE
Last price
$54.05
$82.04
1D performance
-2.60%
+0.38%
AuM$313.37 M$139.64 M
E/R0.35%0.35%
Characteristics
XPH
XHE
Management strategyPassivePassive
ProviderSPDRSPDR
BenchmarkS&P Pharmaceuticals Select Industry IndexS&P Health Care Equipment Select Industry Index
N° of holdings4961
Asset classEquitiesEquities
Trailing 12m distribution yield
Join
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Inception dateJune 19, 2006January 26, 2011
ESGNoNo
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Exposure

Countries

XPH
USA
85.59%
Other
14.41%
XHE
USA
92.71%
Other
7.29%

Sectors

XPH
Health Care
81.97%
Other
18.03%
XHE
Health Care
93.87%
Other
6.13%
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Diversification

XPH

Total weight of top 15 holdings out of 15

32.4%
XHE

Total weight of top 15 holdings out of 15

30.47%

Top 15 holdings

Data as of January 31, 2026
XPH
LIQUIDIA CORPORATION
2.45%
US55287L1017
2.41%
AXSOME THERA CMN STK
2.33%
ORGANON & CO
2.25%
EDGEWISE THERAPEUTICS
2.24%
ELANCO ANIMAL HEALTH INC
2.13%
MERCK & CO INC
2.13%
VIATRIS INC
2.13%
AMNEAL PHARMACEUTICALS INC
2.12%
JOHNSON&JOHNSON
2.08%
ROYALTY PHARMA
2.06%
AMYLYX PHARMACEUTICALS
2.04%
BRISTOL-MYERS SQUIBB
2.03%
XERIS BIOPHARMA HOLDINGS INC
2.00%
ZOETIS INC
2.00%
XHE
NEOGEN
2.63%
INTEGER HOLDINGS
2.17%
PENUMBRA
2.12%
UFP TECHNOLOGY
2.11%
AXOGEN
2.09%
OMNICELL
1.98%
LANTHEUS HOLDINGS
1.98%
BAXTER INTL
1.98%
GLAUKOS
1.97%
DEXCOM
1.94%
DENTSPLY SIRONA
1.92%
BUTTERFLY NETWORK INC
1.92%
ENVISTA HOLDINGS CORP
1.91%
STRYKER
1.88%
GLOBUS MEDICAL
1.86%
Frequently asked questions about XPH and XHE

How have the XPH and XHE ETFs performed in 2026?

As of March 11, 2026, XPH is down -1.12% year-to-date (YTD), while XHE has lost -6.79%. That puts XPH better performer ahead so far this year.

Which ETF is attracting more investor money: XPH or XHE?

Year-to-date, the XPH ETF saw +$88M in flows, compared to -$4M for XHE.

Which ETF is more volatile: XPH or XHE?

Over the past year, XPH had a volatility of 23.08%, while XHE experienced 23.53%.

Which ETF is bigger: XPH or XHE?

As of March 11, 2026, XPH holds $313.37 M in assets under management (AUM), while XHE manages $139.64 M.

What sectors do the XPH and XHE ETFs invest in?

XPH leans toward sectors like Health Care. Meanwhile, XHE focuses on Health Care.

What are the top holdings of the XPH ETF and XHE ETF?

XPH top holdings include LIQUIDIA CORPORATION, US55287L1017 and AXSOME THERA CMN STK. XHE holds in its top three: NEOGEN, INTEGER HOLDINGS and PENUMBRA.

Which ETF is more diversified: XPH or XHE?

XPH holds 57 securities with 32.4% of its assets in the top 15. XHE has 64 securities and a top 15 weight of 30.47%.

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