XPHvsPSCHETF Comparison
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State Street SPDR S&P Pharmaceuticals ETF (XPH) and Invesco S&P SmallCap Health Care ETF (PSCH) belong to the same industry segment: US Health Care. Both ETFs have the same top 1 sector exposures: Healthcare. XPH is more expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.29% for PSCH. XPH is up 14.29% year-to-date (YTD) with +$186M in YTD flows. PSCH performs better with 24.19% YTD performance, and -$1M in YTD flows. Run a side-by-side ETF comparison of XPH and PSCH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XPH vs PSCH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XPH PSCH | -4.31%+2.63% | -6.56%+3.48% | +14.29%+24.19% | +30.94%+27.93% | +86.70%+57.69% | +44.35%-7.08% |
| Flows | XPH PSCH | -$80M-$11M | +$11M+$9M | +$186M-$1M | +$206M-$921K | +$160M-$102M | +$157M-$210M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XPH PSCH | +22.82%+16.95% | +23.36%+19.44% | +20.82%+21.78% | +21.10%+22.92% |
| Max drawdown | XPH PSCH | -16.58%-8.61% | -16.58%-15.36% | -23.45%-22.80% | -30.87%-45.76% |
| Max drawdown duration | XPH PSCH | 69d69d | 69d168d | 322d488d | 1452d1814d |
Trading data
XPH | PSCH | |
Last sale 10/28/2026 at 1:30 PM | $64.55 | $55.06 |
| Previous close 10/27/2026 | $63.96 | $54.75 |
| Consolidated volume 10/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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XPH | PSCH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
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Main metrics
Last update 10/28/2026 at 1:30 PM
Live
Closed
XPH | PSCH | |
|---|---|---|
| Last price | $64.55 | $55.06 |
| 1D performance | +0.92% | +0.57% |
| AuM | $447.54 M | $176.30 M |
| E/R | 0.35% | 0.29% |
Characteristics
XPH | PSCH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | State Street Investment Management | Invesco |
| Benchmark | S&P Pharmaceuticals Select Industry Index | S&P SmallCap 600 Capped Health Care Index |
| N° of holdings | 62 | 69 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 19, 2006 | April 7, 2010 |
| ESG | No | No |
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Exposure
Countries
XPH
USA
89.77%
Other
10.23%
PSCH
USA
94.93%
Other
5.07%
Sectors
XPH
Healthcare
93.27%
Other
6.73%
PSCH
Healthcare
100%
Other
0%
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Diversification
XPH
Total weight of top 15 holdings out of 15
34.13%
PSCH
Total weight of top 15 holdings out of 15
48.62%
Top 15 holdings
Data as of August 31, 2026
XPH
Amylyx Pharmaceuticals, Inc.
3.65%
Crinetics Pharmaceuticals, Inc.
3.60%
MBX Biosciences, Inc.
2.89%
Omeros Corp.
2.68%
Enliven Therapeutics, Inc.
2.28%
Nuvation Bio, Inc.
2.12%
Corcept Therapeutics, Inc.
2.11%
Eton Pharmaceuticals, Inc.
2.08%
Perrigo Co. Plc
1.91%
Edgewise Therapeutics, Inc.
1.85%
Nektar Therapeutics
1.83%
Merck & Co., Inc.
1.81%
Trevi Therapeutics, Inc.
1.80%
Tarsus Pharmaceuticals, Inc.
1.76%
Bristol Myers Squibb Co.
1.75%
PSCH
Corcept Therapeutics, Inc.
5.61%
Glaukos Corp.
5.37%
Protagonist Therapeutics, Inc.
4.54%
Alkermes Plc
4.09%
TG Therapeutics, Inc.
3.69%
Teleflex, Inc.
3.06%
PTC Therapeutics, Inc.
2.99%
Ligand Pharmaceuticals, Inc.
2.87%
Merit Medical Systems, Inc.
2.68%
RadNet, Inc.
2.68%
Liquidia Corp.
2.47%
ICU Medical, Inc.
2.20%
Indivior Pharmaceuticals, Inc.
2.16%
Integer Holdings Corp.
2.14%
Concentra Group Holdings Parent, Inc.
2.07%
Frequently asked questions about XPH and PSCH
How have the XPH and PSCH ETFs performed in 2026?
As of October 27, 2026, XPH is up 14.29% year-to-date (YTD), while PSCH has returned 24.19%. That puts PSCH better performer ahead so far this year.
Which ETF is attracting more investor money: XPH or PSCH?
Year-to-date, the XPH ETF saw +$186M in flows, compared to -$1M for PSCH.
Which ETF is more volatile: XPH or PSCH?
Over the past year, XPH had a volatility of 23.36%, while PSCH experienced 19.44%.
Which ETF is bigger: XPH or PSCH?
As of October 27, 2026, XPH holds $447.54 M in assets under management (AUM), while PSCH manages $176.30 M.
What sectors do the XPH and PSCH ETFs invest in?
XPH leans toward sectors like Healthcare. Meanwhile, PSCH focuses on Healthcare.
What are the top holdings of the XPH ETF and PSCH ETF?
XPH top holdings include Amylyx Pharmaceuticals, Inc., Crinetics Pharmaceuticals, Inc. and MBX Biosciences, Inc.. PSCH holds in its top three: Corcept Therapeutics, Inc., Glaukos Corp. and Protagonist Therapeutics, Inc..
Which ETF is more diversified: XPH or PSCH?
XPH holds 62 securities with 34.13% of its assets in the top 15. PSCH has 69 securities and a top 15 weight of 48.62%.
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