XPHvsARKGETF Comparison
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State Street SPDR S&P Pharmaceuticals ETF (XPH) belongs to the US Health Care segment. ARK Genomic Revolution ETF (ARKG) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. XPH is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.75% for ARKG. XPH is up 2.61% year-to-date (YTD) with +$116M in YTD flows. ARKG performs better with 5.94% YTD performance, and -$42M in YTD flows. Run a side-by-side ETF comparison of XPH and ARKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XPH vs ARKG performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XPH ARKG | +9.68%+16.14% | +2.44%-9.58% | +2.61%+5.94% | +44.99%+45.11% | +40.83%+2.55% | +22.16%-64.83% |
| Flows | XPH ARKG | +$25M-$12M | +$82M-$109M | +$116M-$42M | +$141M-$136M | +$48M-$620M | +$64M-$3.03B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XPH ARKG | +24.78%+43.01% | +21.12%+41.42% | +19.49%+42.56% | +20.45%+45.34% |
| Max drawdown | XPH ARKG | -11.78%-27.52% | -11.78%-27.52% | -23.45%-51.98% | -31.59%-80.16% |
| Max drawdown duration | XPH ARKG | 50d90d | 50d90d | 322d1008d | 1566d1758d |
Trading data
XPH | ARKG | |
Last sale 4/24/2026 at 1:30 PM | $57.40 | $29.54 |
| Previous close 04/23/2026 | $57.20 | $29.80 |
| Consolidated volume 04/23/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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ARKG
is actively managed and doesn’t replicate an indexXPH | ARKG | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
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Main metrics
Last update 4/24/2026 at 1:30 PM
Live
Closed
XPH | ARKG | |
|---|---|---|
| Last price | $57.40 | $29.54 |
| 1D performance | +0.35% | -0.87% |
| AuM | $353.54 M | $1.20 B |
| E/R | 0.35% | 0.75% |
Characteristics
XPH | ARKG | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | State Street Investment Management | Ark Investment |
| Benchmark | S&P Pharmaceuticals Select Industry Index | - |
| N° of holdings | 48 | 27 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 19, 2006 | April 2, 2019 |
| ESG | No | No |
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Exposure
Countries
XPH
USA
87.77%
Other
12.23%
ARKG
USA
70.4%
Switzerland
9.23%
Other
20.37%
Sectors
XPH
Health Care
82.36%
Other
17.64%
ARKG
Health Care
78.38%
Other
21.62%
Diversification
XPH
Total weight of top 15 holdings out of 15
30.65%
ARKG
Total weight of top 15 holdings out of 15
62.5%
Top 15 holdings
Data as of March 31, 2026
XPH
US29337E1029
2.45%
CORCEPT THERAPEUTICS
2.29%
TERNS PHARMACEUTICALS
2.16%
PERRIGO CO PLC
2.10%
AXSOME THERA CMN STK
2.03%
INNOVIVA INC
1.99%
MERCK & CO INC
1.98%
PFIZER
1.97%
ROYALTY PHARMA
1.97%
ELANCO ANIMAL HEALTH INC
1.96%
JAZZ PHARMACEUTICALS
1.96%
ESPERION THERAPEUTICS
1.95%
EDGEWISE THERAPEUTICS
1.95%
US55287L1017
1.95%
BRISTOL-MYERS SQUIBB
1.94%
ARKG
CRISPR THERAPEUTICS
9.23%
10X GENOMICS INC
6.30%
BEAM THERAPEUTICS
4.86%
PERSONALIS INC
4.69%
NATERA
4.48%
ILLUMINA
4.45%
GUARDANT HEALTH INC
4.21%
INTELLIA THERAPEUTICS INC
3.58%
CAREDX INC/D
3.56%
RECURSION PHARMACEUTICALS
3.54%
ABSCI
3.27%
VERACYTE INC/D
2.98%
ADAPTIVE BIOTECHNOLOGIES
2.71%
NURIX THERAPEUTICS
2.45%
SEMA4 HOLDINGS CORP
2.19%
Frequently asked questions about XPH and ARKG
How have the XPH and ARKG ETFs performed in 2026?
As of April 24, 2026, XPH is up 2.61% year-to-date (YTD), while ARKG has returned 5.94%. That puts ARKG better performer ahead so far this year.
Which ETF is attracting more investor money: XPH or ARKG?
Year-to-date, the XPH ETF saw +$116M in flows, compared to -$42M for ARKG.
Which ETF is more volatile: XPH or ARKG?
Over the past year, XPH had a volatility of 21.12%, while ARKG experienced 41.42%.
Which ETF is bigger: XPH or ARKG?
As of April 24, 2026, XPH holds $353.54 M in assets under management (AUM), while ARKG manages $1.20 B.
What sectors do the XPH and ARKG ETFs invest in?
XPH leans toward sectors like Health Care. Meanwhile, ARKG focuses on Health Care.
What are the top holdings of the XPH ETF and ARKG ETF?
XPH top holdings include US29337E1029, CORCEPT THERAPEUTICS and TERNS PHARMACEUTICALS. ARKG holds in its top three: CRISPR THERAPEUTICS, 10X GENOMICS INC and BEAM THERAPEUTICS.
Which ETF is more diversified: XPH or ARKG?
XPH holds 57 securities with 30.65% of its assets in the top 15. ARKG has 27 securities and a top 15 weight of 62.5%.
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