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XPHvsARKGETF Comparison

ETF 1
XPH

SPDR S&P Pharmaceuticals ETF

This fund is part of
US Health Care
-0.3%
Full XPH fund page
VS
ETF 2
ARKG

ARK Genomic Revolution ETF

This fund is part of
BioTech & Genomics
-0.12%
Full ARKG fund page

SPDR S&P Pharmaceuticals ETF (XPH) belongs to the US Health Care segment. ARK Genomic Revolution ETF (ARKG) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. XPH is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.75% for ARKG. XPH is down -1.12% year-to-date (YTD) with +$88M in YTD flows. ARKG performs worse with -4.22% YTD performance, and -$14M in YTD flows. Run a side-by-side ETF comparison of XPH and ARKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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XPH vs ARKG performance and flow charts

Performance

-4.0-2.00.02.04.06.0%Feb 10Feb 18Feb 25Mar 4Mar 11

Cumulative Flows

-50 M0 M50 MFeb 10Feb 18Feb 25Mar 4Mar 11

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Historic performance and flows
Data as of 03/11/2026
1M3MYTD1Y3Y5Y
Perf.
XPH
ARKG
-3.45%-3.97%
-1.36%-10.24%
-1.12%-4.22%
+29.22%+27.40%
+42.98%+1.75%
+9.16%-68.08%
Flows
XPH
ARKG
+$12M-$69M
+$95M-$81M
+$88M-$14M
+$111M-$206M
+$48M-$635M
+$36M-$2.75B
Volatility and drawdown
3M1Y3Y5Y
Volatility
XPH
ARKG
+20.33%+39.15%
+23.08%+44.66%
+19.01%+42.31%
+20.26%+45.26%
Max drawdown
XPH
ARKG
-5.97%-19.50%
-17.10%-23.94%
-23.45%-51.98%
-33.10%-80.33%
Max drawdown duration
XPH
ARKG
14d47d
140d77d
322d965d
1706d1821d
Trading data

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XPH
ARKG
Last sale
3/11/2026 at 7:59 PM
$55.48
$27.00
Previous close
03/11/2026
$55.67
$27.93
Consolidated volume
03/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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ARKG
is actively managed and doesn’t replicate an index

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XPH
ARKG
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/11/2026 at 7:59 PM
Live
Closed
XPH
ARKG
Last price
$55.48
$27.00
1D performance
-0.34%
-3.33%
AuM$313.37 M$1.11 B
E/R0.35%0.75%
Characteristics
XPH
ARKG
Management strategyPassiveActive
ProviderSPDRArk Investment
BenchmarkS&P Pharmaceuticals Select Industry Index-
N° of holdings4930
Asset classEquities-
Trailing 12m distribution yield
Join
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Inception dateJune 19, 2006April 2, 2019
ESGNoNo
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Exposure

Countries

XPH
USA
85.59%
Other
14.41%
ARKG
USA
73.95%
Switzerland
8.01%
Other
18.04%

Sectors

XPH
Health Care
81.97%
Other
18.03%
ARKG
Health Care
80.46%
Other
19.54%
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Diversification

XPH

Total weight of top 15 holdings out of 15

32.4%
ARKG

Total weight of top 15 holdings out of 15

63.79%

Top 15 holdings

Data as of January 31, 2026
XPH
LIQUIDIA CORPORATION
2.45%
US55287L1017
2.41%
AXSOME THERA CMN STK
2.33%
ORGANON & CO
2.25%
EDGEWISE THERAPEUTICS
2.24%
ELANCO ANIMAL HEALTH INC
2.13%
MERCK & CO INC
2.13%
VIATRIS INC
2.13%
AMNEAL PHARMACEUTICALS INC
2.12%
JOHNSON&JOHNSON
2.08%
ROYALTY PHARMA
2.06%
AMYLYX PHARMACEUTICALS
2.04%
BRISTOL-MYERS SQUIBB
2.03%
XERIS BIOPHARMA HOLDINGS INC
2.00%
ZOETIS INC
2.00%
ARKG
CRISPR THERAPEUTICS
8.01%
PERSONALIS INC
6.15%
GUARDANT HEALTH INC
6.00%
10X GENOMICS INC
5.23%
BEAM THERAPEUTICS
4.81%
ILLUMINA
4.53%
NATERA
4.31%
RECURSION PHARMACEUTICALS
4.01%
CAREDX INC/D
3.44%
VERACYTE INC/D
3.29%
ADAPTIVE BIOTECHNOLOGIES
3.13%
INTELLIA THERAPEUTICS INC
3.10%
ABSCI
2.83%
IONIS PHARMACEUTICALS INC
2.62%
SCHRODINGER
2.33%
Frequently asked questions about XPH and ARKG

How have the XPH and ARKG ETFs performed in 2026?

As of March 11, 2026, XPH is down -1.12% year-to-date (YTD), while ARKG has lost -4.22%. That puts XPH better performer ahead so far this year.

Which ETF is attracting more investor money: XPH or ARKG?

Year-to-date, the XPH ETF saw +$88M in flows, compared to -$14M for ARKG.

Which ETF is more volatile: XPH or ARKG?

Over the past year, XPH had a volatility of 23.08%, while ARKG experienced 44.66%.

Which ETF is bigger: XPH or ARKG?

As of March 11, 2026, XPH holds $313.37 M in assets under management (AUM), while ARKG manages $1.11 B.

What sectors do the XPH and ARKG ETFs invest in?

XPH leans toward sectors like Health Care. Meanwhile, ARKG focuses on Health Care.

What are the top holdings of the XPH ETF and ARKG ETF?

XPH top holdings include LIQUIDIA CORPORATION, US55287L1017 and AXSOME THERA CMN STK. ARKG holds in its top three: CRISPR THERAPEUTICS, PERSONALIS INC and GUARDANT HEALTH INC.

Which ETF is more diversified: XPH or ARKG?

XPH holds 57 securities with 32.4% of its assets in the top 15. ARKG has 30 securities and a top 15 weight of 63.79%.

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