TMEDvsIHEETF Comparison
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T. Rowe Price Health Care ETF (TMED) and iShares U.S. Pharmaceuticals ETF (IHE) belong to the same industry segment: US Health Care. TMED's top 3 sector exposures are Healthcare, Consumer Non-Cyclicals and Non-Corporate. In contrast, IHE's top sector exposures are Healthcare and Non-Corporate. TMED is more expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.37% for IHE. TMED is up 16.23% year-to-date (YTD) with +$15M in YTD flows. IHE performs better with 21.99% YTD performance, and +$500M in YTD flows. Run a side-by-side ETF comparison of TMED and IHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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TMED vs IHE performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/22/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | TMED IHE | -0.47%+1.25% | +2.02%+0.82% | +16.23%+21.99% | +21.78%+39.12% | n/a+87.20% | n/a+79.04% |
| Flows | TMED IHE | +$2M-$129M | +$10M+$77M | +$15M+$500M | +$16M+$664M | -+$758M | -+$754M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | TMED IHE | +19.33%+18.62% | +18.68%+18.66% | n/a+17.25% | n/a+16.78% |
| Max drawdown | TMED IHE | -10.10%-9.67% | -11.09%-9.67% | n/a-16.04% | n/a-16.12% |
| Max drawdown duration | TMED IHE | 64d65d | 125d65d | n/a210d | n/a669d |
Trading data
TMED | IHE | |
Last sale 10/23/2026 at 1:30 PM | $34.08 | $102.51 |
| Previous close 10/22/2026 | $34.49 | $104.78 |
| Consolidated volume 10/22/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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TMED
is actively managed and doesn’t replicate an indexTMED | IHE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 10/23/2026 at 1:30 PM
Live
Closed
TMED | IHE | |
|---|---|---|
| Last price | $34.08 | $102.51 |
| 1D performance | -1.20% | -2.17% |
| AuM | $34.50 M | $1.54 B |
| E/R | 0.44% | 0.37% |
Characteristics
TMED | IHE | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | T. Rowe Price | iShares |
| Benchmark | - | Dow Jones U.S. Select Pharmaceuticals Index |
| N° of holdings | 106 | 57 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 11, 2025 | May 1, 2006 |
| ESG | No | No |
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Exposure
Countries
TMED
USA
92.86%
Other
7.14%
IHE
USA
95.75%
Other
4.25%
Sectors
TMED
Healthcare
98.26%
Other
1.74%
IHE
Healthcare
99.75%
Other
0.25%
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Diversification
TMED
Total weight of top 15 holdings out of 15
56.93%
IHE
Total weight of top 15 holdings out of 15
84.42%
Top 15 holdings
Data as of August 31, 2026
TMED
Eli Lilly & Co.
13.87%
UnitedHealth Group, Inc.
5.32%
Alnylam Pharmaceuticals, Inc.
5.20%
Thermo Fisher Scientific, Inc.
3.74%
Cencora, Inc.
3.65%
Insulet Corp.
3.23%
Gilead Sciences, Inc.
2.99%
Agilent Technologies, Inc.
2.85%
Elanco Animal Health, Inc.
2.63%
Dyne Therapeutics, Inc.
2.47%
Boston Scientific Corp.
2.25%
Stryker Corp.
2.21%
Danaher Corp.
2.20%
Waters Corp.
2.17%
West Pharmaceutical Services, Inc.
2.16%
IHE
Johnson & Johnson
22.45%
Eli Lilly & Co.
20.50%
Merck & Co., Inc.
5.00%
Bristol Myers Squibb Co.
4.84%
Royalty Pharma Plc
4.54%
Pfizer Inc.
4.48%
Viatris, Inc.
4.19%
Zoetis, Inc.
3.82%
Jazz Pharmaceuticals Plc
3.43%
Elanco Animal Health, Inc.
2.61%
Corcept Therapeutics, Inc.
2.36%
Crinetics Pharmaceuticals, Inc.
1.95%
Axsome Therapeutics, Inc.
1.87%
Ligand Pharmaceuticals, Inc.
1.24%
Definium Therapeutics, Inc.
1.12%
Frequently asked questions about TMED and IHE
How have the TMED and IHE ETFs performed in 2026?
As of October 22, 2026, TMED is up 16.23% year-to-date (YTD), while IHE has returned 21.99%. That puts IHE better performer ahead so far this year.
Which ETF is attracting more investor money: TMED or IHE?
Year-to-date, the TMED ETF saw +$15M in flows, compared to +$500M for IHE.
Which ETF is more volatile: TMED or IHE?
Over the past year, TMED had a volatility of 18.68%, while IHE experienced 18.66%.
Which ETF is bigger: TMED or IHE?
As of October 22, 2026, TMED holds $34.50 M in assets under management (AUM), while IHE manages $1.54 B.
What sectors do the TMED and IHE ETFs invest in?
TMED leans toward sectors like Healthcare. Meanwhile, IHE focuses on Healthcare.
What are the top holdings of the TMED ETF and IHE ETF?
TMED top holdings include Eli Lilly & Co., UnitedHealth Group, Inc. and Alnylam Pharmaceuticals, Inc.. IHE holds in its top three: Johnson & Johnson, Eli Lilly & Co. and Merck & Co., Inc..
Which ETF is more diversified: TMED or IHE?
TMED holds 106 securities with 56.93% of its assets in the top 15. IHE has 57 securities and a top 15 weight of 84.42%.
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Latest news about TMED & IHE
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