QQQSvsBBCETF Comparison
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Invesco NASDAQ Future Gen 200 ETF (QQQS) belongs to the US Small Cap segment. Virtus LifeSci Biotech Clinical Trials ETF (BBC) is part of the Tomorrow's Treatments segment. QQQS's top 3 sector exposures are Healthcare, Technology and Consumer Cyclicals. In contrast, BBC's top sector exposures are Healthcare. QQQS is less expensive with a Total Expense Ratio (TER) of 0.2%, versus 0.65% for BBC. QQQS is up 24.94% year-to-date (YTD) with +$11M in YTD flows. BBC performs worse with 24.86% YTD performance, and +$5M in YTD flows. Run a side-by-side ETF comparison of QQQS and BBC below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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QQQS vs BBC performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/16/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | QQQS BBC | -5.07%-9.12% | +2.54%+12.12% | +24.94%+24.86% | +37.98%+102.94% | +83.83%+141.05% | n/a+3.72% |
| Flows | QQQS BBC | +$4M- | +$5M+$83K | +$11M+$5M | +$13M+$12M | +$14M+$16M | -+$8M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | QQQS BBC | +21.47%+33.55% | +26.98%+36.27% | +29.01%+37.28% | n/a+39.65% |
| Max drawdown | QQQS BBC | -7.41%-13.66% | -13.66%-14.64% | -34.40%-54.25% | n/a-70.43% |
| Max drawdown duration | QQQS BBC | 41d28d | 81d60d | 253d340d | n/a1666d |
Trading data
QQQS | BBC | |
Last sale 9/17/2026 at 2:56 PM | $43.38 | $49.40 |
| Previous close 09/16/2026 | $42.54 | $48.19 |
| Consolidated volume 09/16/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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QQQS | BBC | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/17/2026 at 2:56 PM
Live
Closed
QQQS | BBC | |
|---|---|---|
| Last price | $43.38 | $49.40 |
| 1D performance | +1.97% | +2.50% |
| AuM | $25.93 M | $45.89 M |
| E/R | 0.2% | 0.65% |
Characteristics
QQQS | BBC | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | Invesco | VIRTUS Investment Partners |
| Benchmark | Nasdaq Innovators Completion Cap Index | LifeSci Biotechnology Clinical Trials Index |
| N° of holdings | 200 | 127 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | October 13, 2022 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
QQQS
USA
85.52%
Other
14.48%
BBC
USA
86.49%
Other
13.51%
Sectors
QQQS
Healthcare
59.03%
Technology
19.7%
Other
21.27%
BBC
Healthcare
95.06%
Other
4.94%
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Diversification
QQQS
Total weight of top 15 holdings out of 15
11.64%
BBC
Total weight of top 15 holdings out of 15
15.32%
Top 15 holdings
Data as of July 31, 2026
QQQS
Agenus, Inc.
1.01%
Cybin, Inc.
0.93%
Xencor, Inc.
0.88%
10X Genomics, Inc.
0.87%
Newell Brands, Inc.
0.81%
AtriCure, Inc.
0.79%
MillerKnoll, Inc.
0.75%
Dentsply Sirona, Inc.
0.72%
Groupon, Inc.
0.72%
Q32 Bio, Inc.
0.71%
Orthofix Medical, Inc.
0.70%
SI-BONE, Inc.
0.70%
Progress Software Corp.
0.69%
TriSalus Life Sciences, Inc.
0.68%
Merit Medical Systems, Inc.
0.68%
BBC
First Tracks Biotherapeutics, Inc.
1.57%
Monopar Therapeutics, Inc.
1.22%
MBX Biosciences, Inc.
1.14%
Zenas BioPharma, Inc.
1.09%
Xencor, Inc.
1.06%
Apogee Therapeutics, Inc.
1.00%
REGENXBIO, Inc.
0.96%
Oric Pharmaceuticals, Inc.
0.96%
Dyne Therapeutics, Inc.
0.93%
uniQure NV
0.91%
SELLAS Life Sciences Group, Inc.
0.91%
Nurix Therapeutics, Inc.
0.91%
Vor Biopharma, Inc.
0.89%
Erasca, Inc.
0.89%
Amylyx Pharmaceuticals, Inc.
0.88%
Frequently asked questions about QQQS and BBC
How have the QQQS and BBC ETFs performed in 2026?
As of September 16, 2026, QQQS is up 24.94% year-to-date (YTD), while BBC has returned 24.86%. That puts QQQS better performer ahead so far this year.
Which ETF is attracting more investor money: QQQS or BBC?
Year-to-date, the QQQS ETF saw +$11M in flows, compared to +$5M for BBC.
Which ETF is more volatile: QQQS or BBC?
Over the past year, QQQS had a volatility of 26.98%, while BBC experienced 36.27%.
Which ETF is bigger: QQQS or BBC?
As of September 16, 2026, QQQS holds $25.93 M in assets under management (AUM), while BBC manages $45.89 M.
What sectors do the QQQS and BBC ETFs invest in?
QQQS leans toward sectors like Healthcare and Technology. Meanwhile, BBC focuses on Healthcare.
What are the top holdings of the QQQS ETF and BBC ETF?
QQQS top holdings include Agenus, Inc., Cybin, Inc. and Xencor, Inc.. BBC holds in its top three: First Tracks Biotherapeutics, Inc., Monopar Therapeutics, Inc. and MBX Biosciences, Inc..
Which ETF is more diversified: QQQS or BBC?
QQQS holds 200 securities with 11.64% of its assets in the top 15. BBC has 127 securities and a top 15 weight of 15.32%.
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Latest news about QQQS & BBC
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