PTHvsXPHETF Comparison
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Invesco DWA Healthcare Momentum ETF (PTH) and State Street SPDR S&P Pharmaceuticals ETF (XPH) belong to the same industry segment: US Health Care. PTH's top 2 sector exposures are Healthcare and Consumer Non-Cyclicals. In contrast, XPH's top sector exposures are Healthcare. PTH is more expensive with a Total Expense Ratio (TER) of 0.72%, versus 0.35% for XPH. PTH is up 17.67% year-to-date (YTD) with +$145M in YTD flows. XPH performs worse with 12.1% YTD performance, and +$186M in YTD flows. Run a side-by-side ETF comparison of PTH and XPH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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PTH vs XPH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/23/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | PTH XPH | -3.42%-5.42% | -1.48%-8.29% | +17.67%+12.10% | +28.89%+29.83% | +104.86%+79.04% | +12.93%+38.62% |
| Flows | PTH XPH | +$9M-$80M | +$57M+$14M | +$145M+$186M | +$155M+$206M | +$98M+$160M | -$114M+$157M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | PTH XPH | +28.93%+22.68% | +26.81%+23.32% | +26.12%+20.82% | +25.90%+21.10% |
| Max drawdown | PTH XPH | -12.72%-16.58% | -12.72%-16.58% | -27.71%-23.45% | -47.24%-30.87% |
| Max drawdown duration | PTH XPH | 65d65d | 65d65d | 353d322d | 1688d1452d |
Trading data
PTH | XPH | |
Last sale 10/23/2026 at 1:30 PM | $58.52 | $62.70 |
| Previous close 10/22/2026 | $58.91 | $64.28 |
| Consolidated volume 10/22/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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PTH | XPH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 10/23/2026 at 1:30 PM
Live
Closed
PTH | XPH | |
|---|---|---|
| Last price | $58.52 | $62.70 |
| 1D performance | -0.66% | -2.46% |
| AuM | $285.48 M | $438.96 M |
| E/R | 0.72% | 0.35% |
Characteristics
PTH | XPH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | Invesco | State Street Investment Management |
| Benchmark | Dorsey Wright Healthcare Technical Leaders Index | S&P Pharmaceuticals Select Industry Index |
| N° of holdings | 54 | 62 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | October 12, 2006 | June 19, 2006 |
| ESG | No | No |
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Exposure
Countries
PTH
USA
90%
Other
10%
XPH
USA
89.77%
Other
10.23%
Sectors
PTH
Healthcare
99.31%
Other
0.69%
XPH
Healthcare
93.27%
Other
6.73%
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Diversification
PTH
Total weight of top 15 holdings out of 15
49.11%
XPH
Total weight of top 15 holdings out of 15
34.13%
Top 15 holdings
Data as of August 31, 2026
PTH
Revolution Medicines, Inc.
5.32%
Roivant Sciences Ltd.
5.01%
Guardant Health, Inc.
4.73%
Moderna, Inc.
4.51%
BrightSpring Health Services, Inc.
3.76%
Axsome Therapeutics, Inc.
3.57%
Erasca, Inc.
2.89%
10X Genomics, Inc.
2.85%
Oruka Therapeutics, Inc.
2.50%
Replimune Group, Inc.
2.46%
Twist Bioscience Corp.
2.43%
Travere Therapeutics, Inc.
2.38%
Axogen, Inc.
2.31%
Liquidia Corp.
2.29%
Relay Therapeutics, Inc.
2.12%
XPH
Amylyx Pharmaceuticals, Inc.
3.65%
Crinetics Pharmaceuticals, Inc.
3.60%
MBX Biosciences, Inc.
2.89%
Omeros Corp.
2.68%
Enliven Therapeutics, Inc.
2.28%
Nuvation Bio, Inc.
2.12%
Corcept Therapeutics, Inc.
2.11%
Eton Pharmaceuticals, Inc.
2.08%
Perrigo Co. Plc
1.91%
Edgewise Therapeutics, Inc.
1.85%
Nektar Therapeutics
1.83%
Merck & Co., Inc.
1.81%
Trevi Therapeutics, Inc.
1.80%
Tarsus Pharmaceuticals, Inc.
1.76%
Bristol Myers Squibb Co.
1.75%
Frequently asked questions about PTH and XPH
How have the PTH and XPH ETFs performed in 2026?
As of October 23, 2026, PTH is up 17.67% year-to-date (YTD), while XPH has returned 12.1%. That puts PTH better performer ahead so far this year.
Which ETF is attracting more investor money: PTH or XPH?
Year-to-date, the PTH ETF saw +$145M in flows, compared to +$186M for XPH.
Which ETF is more volatile: PTH or XPH?
Over the past year, PTH had a volatility of 26.81%, while XPH experienced 23.32%.
Which ETF is bigger: PTH or XPH?
As of October 23, 2026, PTH holds $285.48 M in assets under management (AUM), while XPH manages $438.96 M.
What sectors do the PTH and XPH ETFs invest in?
PTH leans toward sectors like Healthcare. Meanwhile, XPH focuses on Healthcare.
What are the top holdings of the PTH ETF and XPH ETF?
PTH top holdings include Revolution Medicines, Inc., Roivant Sciences Ltd. and Guardant Health, Inc.. XPH holds in its top three: Amylyx Pharmaceuticals, Inc., Crinetics Pharmaceuticals, Inc. and MBX Biosciences, Inc..
Which ETF is more diversified: PTH or XPH?
PTH holds 54 securities with 49.11% of its assets in the top 15. XPH has 62 securities and a top 15 weight of 34.13%.
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Latest news about PTH & XPH
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XPH
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November 20, 2023
XPH
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September 23, 2022
PTH
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