PILLvsUPROETF Comparison
Direxion Daily Pharmaceutical & Medical Bull 3X Shares ETF
Direxion Daily Pharmaceutical & Medical Bull 3X Shares ETF (PILL) and ProShares UltraPro S&P500 ETF (UPRO) belong to the same industry segment: Leveraged Equity. PILL is more expensive with a Total Expense Ratio (TER) of 1.22%, versus 0.89% for UPRO. PILL is up 14.62% year-to-date (YTD) with -$4M in YTD flows. UPRO performs better with 27.56% YTD performance, and -$499M in YTD flows. Run a side-by-side ETF comparison of PILL and UPRO below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
PILL vs UPRO performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | PILL UPRO | -18.37%-1.12% | -27.18%+8.05% | +14.62%+27.56% | +65.29%+23.43% | +178.59%+313.59% | -18.57%+124.84% |
| Flows | PILL UPRO | -$774K+$136M | -$774K-$73M | -$4M-$499M | -$3M-$473M | -$7M-$2.12B | -$17M-$1.48B |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | PILL UPRO | +67.77%+33.40% | +69.76%+38.13% | +62.47%+44.77% | +63.79%+50.96% |
| Max drawdown | PILL UPRO | -44.35%-9.86% | -44.35%-26.82% | -60.51%-49.02% | -82.09%-63.96% |
| Max drawdown duration | PILL UPRO | 68d74d | 68d94d | 375d228d | 1743d892d |
PILL | UPRO | |
Last sale 10/26/2026 at 1:30 PM | $14.01 | $147.05 |
| Previous close 10/26/2026 | $13.90 | $144.04 |
| Consolidated volume 10/26/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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PILL | UPRO | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
PILL | UPRO | |
|---|---|---|
| Last price | $14.01 | $147.05 |
| 1D performance | +0.79% | +2.09% |
| AuM | $14.73 M | $5.41 B |
| E/R | 1.22% | 0.89% |
Exposure data will be available soon
