OZEMvsTHNRETF Comparison
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Roundhill GLP-1 & Weight Loss ETF (OZEM) and Amplify Weight Loss Drug & Treatment ETF (THNR) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Healthcare. Both OZEM and THNR have the same Total Expense Ratio (TER) of 0.59%. OZEM is down -5.02% year-to-date (YTD) with +$22M in YTD flows. THNR performs better with 1.97% YTD performance, and +$2M in YTD flows. Run a side-by-side ETF comparison of OZEM and THNR below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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OZEM vs THNR performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | OZEM THNR | -0.73%-0.57% | +5.00%+7.01% | -5.02%+1.97% | +23.49%+10.18% | n/an/a | n/an/a |
| Flows | OZEM THNR | +$10M+$769K | +$9M+$769K | +$22M+$2M | +$22M+$2M | -- | -- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | OZEM THNR | +21.47%+19.14% | +22.73%+17.87% | n/an/a | n/an/a |
| Max drawdown | OZEM THNR | -6.63%-5.17% | -19.51%-12.38% | n/an/a | n/an/a |
| Max drawdown duration | OZEM THNR | 51d20d | 182d160d | n/an/a | n/an/a |
Trading data
OZEM | THNR | |
Last sale 7/28/2026 at 1:30 PM | $32.81 | $26.09 |
| Previous close 07/27/2026 | $32.55 | $25.75 |
| Consolidated volume 07/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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OZEM
is actively managed and doesn’t replicate an indexOZEM | THNR | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/28/2026 at 1:30 PM
Live
Closed
OZEM | THNR | |
|---|---|---|
| Last price | $32.81 | $26.09 |
| 1D performance | +0.80% | +1.29% |
| AuM | $62.51 M | $5.14 M |
| E/R | 0.59% | 0.59% |
Characteristics
OZEM | THNR | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Roundhill Investments | Amplify ETFs |
| Benchmark | - | VettaFi Weight Loss Drug & Treatment Index |
| N° of holdings | 24 | 20 |
| Asset class | - | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | May 21, 2024 | May 21, 2024 |
| ESG | No | No |
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Exposure
Countries
OZEM
USA
44.42%
Denmark
19.13%
China
16.37%
Other
20.08%
THNR
USA
58.22%
Denmark
13.37%
China
11.24%
Other
17.17%
Sectors
OZEM
Healthcare
99.56%
Other
0.44%
THNR
Healthcare
99.22%
Other
0.78%
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Diversification
OZEM
Total weight of top 15 holdings out of 15
82.24%
THNR
Total weight of top 15 holdings out of 15
85.06%
Top 15 holdings
Data as of June 30, 2026
OZEM
Novo Nordisk A/S
13.29%
Eli Lilly & Co.
13.07%
Pfizer Inc.
6.58%
Kailera Therapeutics, Inc.
6.00%
Viking Therapeutics, Inc.
5.84%
CSPC Pharmaceutical Group Ltd.
5.22%
Chugai Pharmaceutical Co., Ltd.
4.53%
Ascletis Pharma, Inc.
3.95%
Zealand Pharma A/S
3.93%
Amgen, Inc.
3.89%
AstraZeneca PLC
3.89%
Hanmi Pharmaceutical Co., Ltd.
3.33%
Roche Holding AG
3.12%
Structure Therapeutics, Inc.
2.89%
MBX Biosciences, Inc.
2.71%
THNR
Novo Nordisk A/S
9.91%
Eli Lilly & Co.
9.45%
Scholar Rock Holding Corp.
5.76%
Hims & Hers Health, Inc.
5.53%
Viking Therapeutics, Inc.
5.43%
AbbVie, Inc.
5.30%
Regeneron Pharmaceuticals, Inc.
5.01%
Merck & Co., Inc.
5.01%
AstraZeneca PLC
5.00%
Arrowhead Pharmaceuticals, Inc.
4.99%
Roche Holding AG
4.95%
Amgen, Inc.
4.90%
Innovent Biologics, Inc.
4.78%
Chugai Pharmaceutical Co., Ltd.
4.55%
Pfizer Inc.
4.49%
Frequently asked questions about OZEM and THNR
How have the OZEM and THNR ETFs performed in 2026?
As of July 27, 2026, OZEM is down -5.02% year-to-date (YTD), while THNR has returned 1.97%. That puts THNR better performer ahead so far this year.
Which ETF is attracting more investor money: OZEM or THNR?
Year-to-date, the OZEM ETF saw +$22M in flows, compared to +$2M for THNR.
Which ETF is more volatile: OZEM or THNR?
Over the past year, OZEM had a volatility of 22.73%, while THNR experienced 17.87%.
Which ETF is bigger: OZEM or THNR?
As of July 27, 2026, OZEM holds $62.51 M in assets under management (AUM), while THNR manages $5.14 M.
What sectors do the OZEM and THNR ETFs invest in?
OZEM leans toward sectors like Healthcare. Meanwhile, THNR focuses on Healthcare.
What are the top holdings of the OZEM ETF and THNR ETF?
OZEM top holdings include Novo Nordisk A/S, Eli Lilly & Co. and Pfizer Inc.. THNR holds in its top three: Novo Nordisk A/S, Eli Lilly & Co. and Scholar Rock Holding Corp..
Which ETF is more diversified: OZEM or THNR?
OZEM holds 24 securities with 82.24% of its assets in the top 15. THNR has 20 securities and a top 15 weight of 85.06%.
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Latest news about OZEM & THNR
A Deep Dive into the New Amplify Weight Loss Drug & Treatment ETF (THNR)
June 7, 2024
OZEM
THNR
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