OZEMvsCANCETF Comparison
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Roundhill GLP-1 & Weight Loss ETF (OZEM) and Tema Oncology ETF (CANC) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Healthcare. OZEM is less expensive with a Total Expense Ratio (TER) of 0.59%, versus 0.99% for CANC. OZEM is down -5.02% year-to-date (YTD) with +$22M in YTD flows. CANC performs better with 18.41% YTD performance, and +$52M in YTD flows. Run a side-by-side ETF comparison of OZEM and CANC below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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OZEM vs CANC performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | OZEM CANC | -0.73%-0.28% | +5.00%+8.61% | -5.02%+18.41% | +23.49%+53.77% | n/an/a | n/an/a |
| Flows | OZEM CANC | +$10M-$2M | +$9M+$3M | +$22M+$52M | +$22M+$76M | -- | -- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | OZEM CANC | +21.47%+23.01% | +22.73%+22.71% | n/an/a | n/an/a |
| Max drawdown | OZEM CANC | -6.63%-5.93% | -19.51%-9.20% | n/an/a | n/an/a |
| Max drawdown duration | OZEM CANC | 51d47d | 182d67d | n/an/a | n/an/a |
Trading data
OZEM | CANC | |
Last sale 7/28/2026 at 1:30 PM | $32.81 | $41.18 |
| Previous close 07/27/2026 | $32.55 | $41.10 |
| Consolidated volume 07/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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Main metrics
Last update 7/28/2026 at 1:30 PM
Live
Closed
OZEM | CANC | |
|---|---|---|
| Last price | $32.81 | $41.18 |
| 1D performance | +0.80% | +0.20% |
| AuM | $62.51 M | $195.62 M |
| E/R | 0.59% | 0.99% |
Characteristics
OZEM | CANC | |
|---|---|---|
| Management strategy | Active | Active |
| Provider | Roundhill Investments | Tema |
| Benchmark | - | - |
| N° of holdings | 24 | 56 |
| Asset class | - | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | May 21, 2024 | August 15, 2023 |
| ESG | No | No |
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Exposure
Countries
OZEM
USA
44.42%
Denmark
19.13%
China
16.37%
Other
20.08%
CANC
USA
80.59%
Switzerland
9.85%
Other
9.56%
Sectors
OZEM
Healthcare
99.56%
Other
0.44%
CANC
Healthcare
99.28%
Other
0.72%
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Diversification
OZEM
Total weight of top 15 holdings out of 15
82.24%
CANC
Total weight of top 15 holdings out of 15
55.76%
Top 15 holdings
Data as of June 30, 2026
OZEM
Novo Nordisk A/S
13.29%
Eli Lilly & Co.
13.07%
Pfizer Inc.
6.58%
Kailera Therapeutics, Inc.
6.00%
Viking Therapeutics, Inc.
5.84%
CSPC Pharmaceutical Group Ltd.
5.22%
Chugai Pharmaceutical Co., Ltd.
4.53%
Ascletis Pharma, Inc.
3.95%
Zealand Pharma A/S
3.93%
Amgen, Inc.
3.89%
AstraZeneca PLC
3.89%
Hanmi Pharmaceutical Co., Ltd.
3.33%
Roche Holding AG
3.12%
Structure Therapeutics, Inc.
2.89%
MBX Biosciences, Inc.
2.71%
CANC
Revolution Medicines, Inc.
6.32%
Eli Lilly & Co.
5.24%
Cogent Biosciences, Inc.
4.94%
Novartis AG
4.19%
Roche Holding AG
3.93%
Legend Biotech Corp.
3.70%
Merck & Co., Inc.
3.66%
Bristol Myers Squibb Co.
3.33%
AstraZeneca PLC
3.15%
Johnson & Johnson
3.09%
AbbVie, Inc.
3.08%
Immunome, Inc.
2.87%
Exelixis, Inc.
2.85%
Nuvalent, Inc.
2.73%
IDEAYA Biosciences, Inc.
2.68%
Frequently asked questions about OZEM and CANC
How have the OZEM and CANC ETFs performed in 2026?
As of July 27, 2026, OZEM is down -5.02% year-to-date (YTD), while CANC has returned 18.41%. That puts CANC better performer ahead so far this year.
Which ETF is attracting more investor money: OZEM or CANC?
Year-to-date, the OZEM ETF saw +$22M in flows, compared to +$52M for CANC.
Which ETF is more volatile: OZEM or CANC?
Over the past year, OZEM had a volatility of 22.73%, while CANC experienced 22.71%.
Which ETF is bigger: OZEM or CANC?
As of July 27, 2026, OZEM holds $62.51 M in assets under management (AUM), while CANC manages $195.62 M.
What sectors do the OZEM and CANC ETFs invest in?
OZEM leans toward sectors like Healthcare. Meanwhile, CANC focuses on Healthcare.
What are the top holdings of the OZEM ETF and CANC ETF?
OZEM top holdings include Novo Nordisk A/S, Eli Lilly & Co. and Pfizer Inc.. CANC holds in its top three: Revolution Medicines, Inc., Eli Lilly & Co. and Cogent Biosciences, Inc..
Which ETF is more diversified: OZEM or CANC?
OZEM holds 24 securities with 82.24% of its assets in the top 15. CANC has 56 securities and a top 15 weight of 55.76%.
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Latest news about OZEM & CANC
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