OZEMvsBBPETF Comparison
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Roundhill GLP-1 & Weight Loss ETF (OZEM) and Virtus LifeSci Biotech Products ETF (BBP) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Healthcare. OZEM is more expensive with a Total Expense Ratio (TER) of 0.59%, versus 0.34% for BBP. OZEM is down -4.17% year-to-date (YTD) with +$22M in YTD flows. BBP performs better with 22.38% YTD performance, and +$40M in YTD flows. Run a side-by-side ETF comparison of OZEM and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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OZEM vs BBP performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/28/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | OZEM BBP | +0.15%+1.64% | +6.60%+16.89% | -4.17%+22.38% | +24.59%+57.67% | n/a+76.64% | n/a+89.75% |
| Flows | OZEM BBP | +$10M+$10M | +$9M+$28M | +$22M+$40M | +$22M+$52M | -+$55M | -+$48M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | OZEM BBP | +21.48%+26.30% | +22.70%+23.98% | n/a+24.26% | n/a+26.44% |
| Max drawdown | OZEM BBP | -6.63%-7.49% | -19.51%-9.59% | n/a-25.54% | n/a-37.61% |
| Max drawdown duration | OZEM BBP | 51d44d | 183d48d | n/a292d | n/a586d |
Trading data
OZEM | BBP | |
Last sale 7/29/2026 at 1:30 PM | $32.66 | $96.70 |
| Previous close 07/28/2026 | $32.81 | $97.69 |
| Consolidated volume 07/28/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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OZEM
is actively managed and doesn’t replicate an indexOZEM | BBP | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
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Main metrics
Last update 7/29/2026 at 1:30 PM
Live
Closed
OZEM | BBP | |
|---|---|---|
| Last price | $32.66 | $96.70 |
| 1D performance | -0.46% | -1.02% |
| AuM | $63.07 M | $97.61 M |
| E/R | 0.59% | 0.34% |
Characteristics
OZEM | BBP | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Roundhill Investments | VIRTUS Investment Partners |
| Benchmark | - | LifeSci Biotechnology Products Index |
| N° of holdings | 24 | 66 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | May 21, 2024 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
OZEM
USA
44.42%
Denmark
19.13%
China
16.37%
Other
20.08%
BBP
USA
89.11%
Other
10.89%
Sectors
OZEM
Healthcare
99.56%
Other
0.44%
BBP
Healthcare
89.47%
Other
10.53%
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Diversification
OZEM
Total weight of top 15 holdings out of 15
82.24%
BBP
Total weight of top 15 holdings out of 15
87.15%
Top 15 holdings
Data as of June 30, 2026
OZEM
Novo Nordisk A/S
13.29%
Eli Lilly & Co.
13.07%
Pfizer Inc.
6.58%
Kailera Therapeutics, Inc.
6.00%
Viking Therapeutics, Inc.
5.84%
CSPC Pharmaceutical Group Ltd.
5.22%
Chugai Pharmaceutical Co., Ltd.
4.53%
Ascletis Pharma, Inc.
3.95%
Zealand Pharma A/S
3.93%
AstraZeneca PLC
3.89%
Amgen, Inc.
3.89%
Hanmi Pharmaceutical Co., Ltd.
3.33%
Roche Holding AG
3.12%
Structure Therapeutics, Inc.
2.89%
MBX Biosciences, Inc.
2.71%
BBP
Verastem, Inc.
44.58%
Legend Biotech Corp.
41.98%
Gilead Sciences, Inc.
0.05%
Incyte Corp.
0.05%
Zymeworks, Inc.
0.05%
Zai Lab Ltd.
0.05%
PTC Therapeutics, Inc.
0.05%
BioCryst Pharmaceuticals, Inc.
0.05%
Ionis Pharmaceuticals, Inc.
0.05%
Protagonist Therapeutics, Inc.
0.05%
Sarepta Therapeutics, Inc.
0.05%
Rhythm Pharmaceuticals, Inc.
0.05%
Kura Oncology, Inc.
0.05%
Arcutis Biotherapeutics, Inc.
0.05%
Geron Corp.
0.05%
Frequently asked questions about OZEM and BBP
How have the OZEM and BBP ETFs performed in 2026?
As of July 28, 2026, OZEM is down -4.17% year-to-date (YTD), while BBP has returned 22.38%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: OZEM or BBP?
Year-to-date, the OZEM ETF saw +$22M in flows, compared to +$40M for BBP.
Which ETF is more volatile: OZEM or BBP?
Over the past year, OZEM had a volatility of 22.7%, while BBP experienced 23.98%.
Which ETF is bigger: OZEM or BBP?
As of July 28, 2026, OZEM holds $63.07 M in assets under management (AUM), while BBP manages $97.61 M.
What sectors do the OZEM and BBP ETFs invest in?
OZEM leans toward sectors like Healthcare. Meanwhile, BBP focuses on Healthcare.
What are the top holdings of the OZEM ETF and BBP ETF?
OZEM top holdings include Novo Nordisk A/S, Eli Lilly & Co. and Pfizer Inc.. BBP holds in its top three: Verastem, Inc., Legend Biotech Corp. and Gilead Sciences, Inc..
Which ETF is more diversified: OZEM or BBP?
OZEM holds 24 securities with 82.24% of its assets in the top 15. BBP has 66 securities and a top 15 weight of 87.15%.
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Latest news about OZEM & BBP
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