MEDXvsHRTSETF Comparison
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Horizon Kinetics Medical ETF (MEDX) and Tema GLP-1, Obesity & Cardiometabolic ETF (HRTS) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Health Care. MEDX is less expensive with a Total Expense Ratio (TER) of 0.85%, versus 0.99% for HRTS. MEDX is down -4.65% year-to-date (YTD) with -$799K in YTD flows. HRTS performs worse with -7.09% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of MEDX and HRTS below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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MEDX vs HRTS performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/29/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | MEDX HRTS | -2.05%+0.22% | -5.54%-7.83% | -4.65%-7.09% | +20.10%+15.13% | +12.19%n/a | n/an/a |
| Flows | MEDX HRTS | --$1M | -$799K-$4M | -$799K-$2M | -$2M-$12M | -$3M- | -- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | MEDX HRTS | +19.26%+16.39% | +18.69%+16.33% | +16.63%n/a | n/an/a |
| Max drawdown | MEDX HRTS | -10.65%-9.68% | -10.65%-10.68% | -23.05%n/a | n/an/a |
| Max drawdown duration | MEDX HRTS | 59d59d | 59d112d | 393dn/a | n/an/a |
Trading data
MEDX | HRTS | |
Last sale 4/29/2026 at 2:36 PM | $31.56 | $32.74 |
| Previous close 04/29/2026 | $31.94 | $33.15 |
| Consolidated volume 04/29/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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Main metrics
Last update 4/29/2026 at 2:36 PM
Live
Closed
MEDX | HRTS | |
|---|---|---|
| Last price | $31.56 | $32.74 |
| 1D performance | -1.20% | -1.22% |
| AuM | $17.27 M | $48.91 M |
| E/R | 0.85% | 0.99% |
Characteristics
MEDX | HRTS | |
|---|---|---|
| Management strategy | Active | Active |
| Provider | Horizon Kinetics LLC | Tema |
| Benchmark | - | - |
| N° of holdings | 25 | 38 |
| Asset class | - | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 27, 2023 | November 21, 2023 |
| ESG | No | No |
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Exposure
Countries
MEDX
USA
79.24%
Other
20.76%
HRTS
USA
82.47%
Other
17.53%
Sectors
MEDX
Health Care
79%
Other
21%
HRTS
Health Care
87.86%
Other
12.14%
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Diversification
MEDX
Total weight of top 15 holdings out of 15
82.03%
HRTS
Total weight of top 15 holdings out of 15
61.52%
Top 15 holdings
Data as of March 31, 2026
MEDX
LILLY
15.47%
ABBVIE
8.50%
US66987V1098
7.50%
JOHNSON&JOHNSON
6.05%
ASTRAZENECA
5.78%
BRISTOL-MYERS SQUIBB
5.20%
IONIS PHARMACEUTICALS INC
4.70%
AMGEN-T
4.28%
MERCK & CO INC
4.12%
ALNYLAM PHARMACEUTICALS
4.07%
PFIZER
3.74%
ALKERMES
3.61%
US37733W2044
3.17%
BIOGEN INC
3.04%
REGENERON PHARMACEUTICALS
2.80%
HRTS
LILLY
9.70%
JOHNSON&JOHNSON
4.97%
US7711951043
4.94%
ASTRAZENECA
4.91%
MERCK & CO INC
4.46%
THERMO FISHER SCIENTIFIC
4.06%
UNITEDHEALTH GRP
3.79%
GILEAD SCIENCES
3.66%
NOVARTIS
3.52%
VERTEX PHARMACEUTICALS
3.30%
ABBOTT LABS
3.26%
ABBVIE
3.00%
BRIDGEBIO PHARMA
2.85%
DANAHER
2.81%
BRISTOL-MYERS SQUIBB
2.29%
Frequently asked questions about MEDX and HRTS
How have the MEDX and HRTS ETFs performed in 2026?
As of April 29, 2026, MEDX is down -4.65% year-to-date (YTD), while HRTS has lost -7.09%. That puts MEDX better performer ahead so far this year.
Which ETF is attracting more investor money: MEDX or HRTS?
Year-to-date, the MEDX ETF saw -$799K in flows, compared to -$2M for HRTS.
Which ETF is more volatile: MEDX or HRTS?
Over the past year, MEDX had a volatility of 18.69%, while HRTS experienced 16.33%.
Which ETF is bigger: MEDX or HRTS?
As of April 29, 2026, MEDX holds $17.27 M in assets under management (AUM), while HRTS manages $48.91 M.
What sectors do the MEDX and HRTS ETFs invest in?
MEDX leans toward sectors like Health Care. Meanwhile, HRTS focuses on Health Care.
What are the top holdings of the MEDX ETF and HRTS ETF?
MEDX top holdings include LILLY, ABBVIE and US66987V1098. HRTS holds in its top three: LILLY, JOHNSON&JOHNSON and US7711951043.
Which ETF is more diversified: MEDX or HRTS?
MEDX holds 29 securities with 82.03% of its assets in the top 15. HRTS has 44 securities and a top 15 weight of 61.52%.
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Latest news about MEDX & HRTS
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