MEDXvsHRTSETF Comparison
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Horizon Kinetics Medical ETF (MEDX) and Tema GLP-1, Obesity & Cardiometabolic ETF (HRTS) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Healthcare. MEDX is less expensive with a Total Expense Ratio (TER) of 0.85%, versus 0.99% for HRTS. MEDX is up 8.22% year-to-date (YTD) with -$3M in YTD flows. HRTS performs worse with 5.78% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of MEDX and HRTS below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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MEDX vs HRTS performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/28/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | MEDX HRTS | -3.03%+1.97% | +12.56%+12.66% | +8.22%+5.78% | +31.02%+30.47% | +28.80%n/a | n/an/a |
| Flows | MEDX HRTS | -$883K- | -$2M-$70K | -$3M-$2M | -$3M-$6M | -$4M- | -- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | MEDX HRTS | +21.02%+18.07% | +18.55%+16.11% | +17.31%n/a | n/an/a |
| Max drawdown | MEDX HRTS | -7.93%-4.69% | -10.65%-10.68% | -23.05%n/a | n/an/a |
| Max drawdown duration | MEDX HRTS | 21d21d | 115d170d | 393dn/a | n/an/a |
Trading data
MEDX | HRTS | |
Last sale 7/29/2026 at 1:30 PM | $35.80 | $37.24 |
| Previous close 07/28/2026 | $36.03 | $37.39 |
| Consolidated volume 07/28/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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Main metrics
Last update 7/29/2026 at 1:30 PM
Live
Closed
MEDX | HRTS | |
|---|---|---|
| Last price | $35.80 | $37.24 |
| 1D performance | -0.63% | -0.39% |
| AuM | $17.80 M | $55.69 M |
| E/R | 0.85% | 0.99% |
Characteristics
MEDX | HRTS | |
|---|---|---|
| Management strategy | Active | Active |
| Provider | Horizon Kinetics LLC | Tema |
| Benchmark | - | - |
| N° of holdings | 30 | 43 |
| Asset class | - | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 27, 2023 | November 21, 2023 |
| ESG | No | No |
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Exposure
Countries
MEDX
USA
68.17%
Switzerland
10.22%
United Kingdom
8.49%
Other
13.12%
HRTS
USA
76.55%
Switzerland
7.26%
Other
16.19%
Sectors
MEDX
Healthcare
92.67%
Other
7.33%
HRTS
Healthcare
99.57%
Other
0.43%
Diversification
MEDX
Total weight of top 15 holdings out of 15
81.88%
HRTS
Total weight of top 15 holdings out of 15
64.29%
Top 15 holdings
Data as of June 30, 2026
MEDX
Eli Lilly & Co.
18.51%
AbbVie, Inc.
8.87%
Novartis AG
6.80%
Alkermes Plc
5.79%
Johnson & Johnson
5.58%
AstraZeneca PLC
4.93%
Ionis Pharmaceuticals, Inc.
4.62%
Bristol Myers Squibb Co.
4.40%
Merck & Co., Inc.
3.94%
Amgen, Inc.
3.86%
Alnylam Pharmaceuticals, Inc.
3.30%
Biogen, Inc.
3.07%
Pfizer Inc.
2.87%
GSK Plc
2.70%
CRISPR Therapeutics AG
2.64%
HRTS
Eli Lilly & Co.
11.91%
UnitedHealth Group, Inc.
5.58%
Novo Nordisk A/S
5.25%
Merck & Co., Inc.
4.11%
Roche Holding AG
3.96%
Thermo Fisher Scientific, Inc.
3.91%
AstraZeneca PLC
3.85%
Johnson & Johnson
3.84%
Revolution Medicines, Inc.
3.64%
Cytokinetics, Inc.
3.40%
Novartis AG
3.30%
Gilead Sciences, Inc.
3.09%
Vertex Pharmaceuticals, Inc.
3.04%
Abbott Laboratories
2.71%
Danaher Corp.
2.70%
Frequently asked questions about MEDX and HRTS
How have the MEDX and HRTS ETFs performed in 2026?
As of July 28, 2026, MEDX is up 8.22% year-to-date (YTD), while HRTS has returned 5.78%. That puts MEDX better performer ahead so far this year.
Which ETF is attracting more investor money: MEDX or HRTS?
Year-to-date, the MEDX ETF saw -$3M in flows, compared to -$2M for HRTS.
Which ETF is more volatile: MEDX or HRTS?
Over the past year, MEDX had a volatility of 18.55%, while HRTS experienced 16.11%.
Which ETF is bigger: MEDX or HRTS?
As of July 28, 2026, MEDX holds $17.80 M in assets under management (AUM), while HRTS manages $55.69 M.
What sectors do the MEDX and HRTS ETFs invest in?
MEDX leans toward sectors like Healthcare. Meanwhile, HRTS focuses on Healthcare.
What are the top holdings of the MEDX ETF and HRTS ETF?
MEDX top holdings include Eli Lilly & Co., AbbVie, Inc. and Novartis AG. HRTS holds in its top three: Eli Lilly & Co., UnitedHealth Group, Inc. and Novo Nordisk A/S.
Which ETF is more diversified: MEDX or HRTS?
MEDX holds 30 securities with 81.88% of its assets in the top 15. HRTS has 43 securities and a top 15 weight of 64.29%.
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Latest news about MEDX & HRTS
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