MDEVvsIHEETF Comparison
VS
First Trust Indxx Medical Devices ETF (MDEV) belongs to the Healthcare Technology segment. iShares U.S. Pharmaceuticals ETF (IHE) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. MDEV is more expensive with a Total Expense Ratio (TER) of 0.7%, versus 0.38% for IHE. MDEV is down -10.49% year-to-date (YTD) with - in YTD flows. IHE performs better with 12.18% YTD performance, and +$30M in YTD flows. Run a side-by-side ETF comparison of MDEV and IHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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MDEV vs IHE performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | MDEV IHE | +3.24%+7.66% | -0.93%+9.75% | -10.49%+12.18% | -8.49%+42.29% | -7.39%+69.67% | n/a+64.77% |
| Flows | MDEV IHE | -+$38M | --$98M | -+$30M | +$0K+$164M | -$228K+$261M | -+$294M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | MDEV IHE | +17.80%+19.63% | +16.00%+17.30% | +16.05%+16.52% | n/a+16.23% |
| Max drawdown | MDEV IHE | -10.88%-4.47% | -18.07%-8.48% | -22.64%-16.04% | n/a-16.12% |
| Max drawdown duration | MDEV IHE | 54d15d | 157d81d | 223d210d | n/a669d |
Trading data
MDEV | IHE | |
Last sale 6/15/2026 at 1:30 PM | $18.77 | $93.73 |
| Previous close 06/12/2026 | $18.81 | $94.75 |
| Consolidated volume 06/12/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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MDEV | IHE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/15/2026 at 1:30 PM
Live
Closed
MDEV | IHE | |
|---|---|---|
| Last price | $18.77 | $93.73 |
| 1D performance | -0.23% | -1.08% |
| AuM | $1.88 M | $981.06 M |
| E/R | 0.7% | 0.38% |
Characteristics
MDEV | IHE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | iShares |
| Benchmark | Indxx Global Medical Equipment Index | Dow Jones U.S. Select Pharmaceuticals Index |
| N° of holdings | 46 | 45 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 23, 2021 | May 1, 2006 |
| ESG | No | No |
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Exposure
Countries
MDEV
USA
54.78%
Japan
7.99%
Other
37.22%
IHE
USA
90.2%
Other
9.8%
Sectors
MDEV
Health Care
89.65%
Other
10.35%
IHE
Health Care
95.09%
Other
4.91%
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Diversification
MDEV
Total weight of top 15 holdings out of 15
32.06%
IHE
Total weight of top 15 holdings out of 15
83.6%
Top 15 holdings
Data as of April 30, 2026
MDEV
TELEFLEX
2.37%
WEST PHARM SVCS
2.35%
WUXI APPTEC CO LTD
2.23%
EDWARDS LIFESCIENCES
2.18%
BAXTER INTL
2.16%
INTUITIVE SURGICAL
2.15%
ALIGN TECHNOLOGY
2.12%
DEMANT
2.08%
GLOBUS MEDICAL
2.07%
OLYMPUS
2.07%
MASIMO
2.06%
BIO RAD LABORATORIES
2.06%
AGILENT TECHNOLOGIES
2.06%
SYSMEX
2.05%
CARL ZEISS MEDITEC
2.05%
IHE
JOHNSON&JOHNSON
21.40%
LILLY
21.14%
ROYALTY PHARMA
4.85%
VIATRIS INC
4.75%
BRISTOL-MYERS SQUIBB
4.57%
PFIZER
4.42%
ZOETIS INC
4.34%
MERCK & CO INC
4.25%
JAZZ PHARMACEUTICALS
3.40%
ELANCO ANIMAL HEALTH INC
3.07%
AXSOME THERA CMN STK
2.43%
US45579U1097
1.27%
TERNS PHARMACEUTICALS
1.26%
LIGAND PHARMACEUTICALS
1.25%
CORCEPT THERAPEUTICS
1.20%
Frequently asked questions about MDEV and IHE
How have the MDEV and IHE ETFs performed in 2026?
As of June 12, 2026, MDEV is down -10.49% year-to-date (YTD), while IHE has returned 12.18%. That puts IHE better performer ahead so far this year.
Which ETF is attracting more investor money: MDEV or IHE?
Year-to-date, the MDEV ETF saw - in flows, compared to +$30M for IHE.
Which ETF is more volatile: MDEV or IHE?
Over the past year, MDEV had a volatility of 16%, while IHE experienced 17.3%.
Which ETF is bigger: MDEV or IHE?
As of June 12, 2026, MDEV holds $1.88 M in assets under management (AUM), while IHE manages $981.06 M.
What sectors do the MDEV and IHE ETFs invest in?
MDEV leans toward sectors like Health Care. Meanwhile, IHE focuses on Health Care.
What are the top holdings of the MDEV ETF and IHE ETF?
MDEV top holdings include TELEFLEX, WEST PHARM SVCS and WUXI APPTEC CO LTD. IHE holds in its top three: JOHNSON&JOHNSON, LILLY and ROYALTY PHARMA.
Which ETF is more diversified: MDEV or IHE?
MDEV holds 47 securities with 32.06% of its assets in the top 15. IHE has 57 securities and a top 15 weight of 83.6%.
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