MDEVvsHRTSETF Comparison
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First Trust Indxx Medical Devices ETF (MDEV) belongs to the Healthcare Technology segment. Tema GLP-1, Obesity & Cardiometabolic ETF (HRTS) is part of the Tomorrow's Treatments segment. Both ETFs have the same top 3 sector exposures: and Healthcare. MDEV is less expensive with a Total Expense Ratio (TER) of 0.7%, versus 0.99% for HRTS. MDEV is down -3.05% year-to-date (YTD) with +$994K in YTD flows. HRTS performs better with 4.32% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of MDEV and HRTS below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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MDEV vs HRTS performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/30/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | MDEV HRTS | +6.20%+1.63% | +9.77%+9.49% | -3.05%+4.32% | -0.45%+31.36% | -2.20%n/a | -23.17%n/a |
| Flows | MDEV HRTS | +$994K- | +$994K-$70K | +$994K-$2M | +$994K-$6M | +$767K- | -$23M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | MDEV HRTS | +17.24%+17.44% | +16.50%+16.04% | +16.33%n/a | +19.16%n/a |
| Max drawdown | MDEV HRTS | -3.88%-4.69% | -18.07%-10.68% | -21.75%n/a | -42.16%n/a |
| Max drawdown duration | MDEV HRTS | 11d23d | 205d170d | 205dn/a | 1787dn/a |
Trading data
MDEV | HRTS | |
Last sale 7/31/2026 at 1:30 PM | $20.24 | $36.43 |
| Previous close 07/30/2026 | $20.16 | $36.90 |
| Consolidated volume 07/30/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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HRTS
is actively managed and doesn’t replicate an indexMDEV | HRTS | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/31/2026 at 1:30 PM
Live
Closed
MDEV | HRTS | |
|---|---|---|
| Last price | $20.24 | $36.43 |
| 1D performance | +0.39% | -1.26% |
| AuM | $3.06 M | $54.92 M |
| E/R | 0.7% | 0.99% |
Characteristics
MDEV | HRTS | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | First Trust | Tema |
| Benchmark | Indxx Global Medical Equipment Index | - |
| N° of holdings | 47 | 43 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 23, 2021 | November 21, 2023 |
| ESG | No | No |
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Exposure
Countries
MDEV
USA
55.63%
Japan
7.86%
Other
36.51%
HRTS
USA
76.55%
Switzerland
7.26%
Other
16.19%
Sectors
MDEV
Healthcare
95.26%
Other
4.74%
HRTS
Healthcare
99.57%
Other
0.43%
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Diversification
MDEV
Total weight of top 15 holdings out of 15
35.95%
HRTS
Total weight of top 15 holdings out of 15
64.29%
Top 15 holdings
Data as of June 30, 2026
MDEV
West Pharmaceutical Services, Inc.
2.88%
Demant A/S
2.76%
LivaNova Plc
2.67%
Baxter International, Inc.
2.57%
Revvity, Inc.
2.55%
WuXi AppTec Co., Ltd.
2.41%
Waters Corp.
2.40%
Edwards Lifesciences Corp.
2.40%
Agilent Technologies, Inc.
2.36%
Teleflex, Inc.
2.23%
DexCom, Inc.
2.18%
Bio-Rad Laboratories, Inc.
2.16%
Sonova Holding AG
2.13%
Align Technology, Inc.
2.13%
Sysmex Corp.
2.12%
HRTS
Eli Lilly & Co.
11.91%
UnitedHealth Group, Inc.
5.58%
Novo Nordisk A/S
5.25%
Merck & Co., Inc.
4.11%
Roche Holding AG
3.96%
Thermo Fisher Scientific, Inc.
3.91%
AstraZeneca PLC
3.85%
Johnson & Johnson
3.84%
Revolution Medicines, Inc.
3.64%
Cytokinetics, Inc.
3.40%
Novartis AG
3.30%
Gilead Sciences, Inc.
3.09%
Vertex Pharmaceuticals, Inc.
3.04%
Abbott Laboratories
2.71%
Danaher Corp.
2.70%
Frequently asked questions about MDEV and HRTS
How have the MDEV and HRTS ETFs performed in 2026?
As of July 30, 2026, MDEV is down -3.05% year-to-date (YTD), while HRTS has returned 4.32%. That puts HRTS better performer ahead so far this year.
Which ETF is attracting more investor money: MDEV or HRTS?
Year-to-date, the MDEV ETF saw +$994K in flows, compared to -$2M for HRTS.
Which ETF is more volatile: MDEV or HRTS?
Over the past year, MDEV had a volatility of 16.5%, while HRTS experienced 16.04%.
Which ETF is bigger: MDEV or HRTS?
As of July 30, 2026, MDEV holds $3.06 M in assets under management (AUM), while HRTS manages $54.92 M.
What sectors do the MDEV and HRTS ETFs invest in?
MDEV leans toward sectors like Healthcare. Meanwhile, HRTS focuses on Healthcare.
What are the top holdings of the MDEV ETF and HRTS ETF?
MDEV top holdings include West Pharmaceutical Services, Inc., Demant A/S and LivaNova Plc. HRTS holds in its top three: Eli Lilly & Co., UnitedHealth Group, Inc. and Novo Nordisk A/S.
Which ETF is more diversified: MDEV or HRTS?
MDEV holds 47 securities with 35.95% of its assets in the top 15. HRTS has 43 securities and a top 15 weight of 64.29%.
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Latest news about MDEV & HRTS
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