LFSCvsXPHETF Comparison
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F/m Emerald Life Sciences Innovation ETF (LFSC) belongs to the Life Sciences segment. State Street SPDR S&P Pharmaceuticals ETF (XPH) is part of the US Health Care segment. LFSC's top 3 sector exposures are Health Care and Sovereign. In contrast, XPH's top sector exposures are Health Care LFSC is more expensive with a Total Expense Ratio (TER) of 0.79%, versus 0.35% for XPH. LFSC is up 8.38% year-to-date (YTD) with +$5M in YTD flows. XPH performs worse with 6.83% YTD performance, and +$110M in YTD flows. Run a side-by-side ETF comparison of LFSC and XPH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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LFSC vs XPH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/11/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | LFSC XPH | +3.25%+2.68% | +13.25%+8.04% | +8.38%+6.83% | +60.86%+43.48% | n/a+52.11% | n/a+20.56% |
| Flows | LFSC XPH | +$352K-$8M | -$1M+$17M | +$5M+$110M | +$15M+$133M | -+$51M | -+$63M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | LFSC XPH | +30.50%+25.99% | +26.55%+21.47% | n/a+19.90% | n/a+20.72% |
| Max drawdown | LFSC XPH | -6.53%-8.13% | -16.25%-11.78% | n/a-23.45% | n/a-31.59% |
| Max drawdown duration | LFSC XPH | 20d36d | 168d50d | n/a322d | n/a1566d |
Trading data
LFSC | XPH | |
Last sale 6/11/2026 at 7:14 PM | $39.91 | $60.47 |
| Previous close 06/11/2026 | $38.58 | $59.77 |
| Consolidated volume 06/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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LFSC
is actively managed and doesn’t replicate an indexLFSC | XPH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/11/2026 at 7:14 PM
Live
Closed
LFSC | XPH | |
|---|---|---|
| Last price | $39.91 | $60.47 |
| 1D performance | +3.45% | +1.17% |
| AuM | $106.22 M | $362.12 M |
| E/R | 0.79% | 0.35% |
Characteristics
LFSC | XPH | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Emerald Group | State Street Investment Management |
| Benchmark | - | S&P Pharmaceuticals Select Industry Index |
| N° of holdings | 33 | 48 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | October 31, 2024 | June 19, 2006 |
| ESG | No | No |
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Exposure
Countries
LFSC
USA
91.24%
Other
8.76%
XPH
USA
89.49%
Other
10.51%
Sectors
LFSC
Health Care
73.79%
Other
26.21%
XPH
Health Care
82.05%
Other
17.95%
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Diversification
LFSC
Total weight of top 15 holdings out of 15
69.25%
XPH
Total weight of top 15 holdings out of 15
33.31%
Top 15 holdings
Data as of April 30, 2026
LFSC
COGENT BIOSCIENCES
8.24%
TRAVERE THERAPEUTICS INC
6.94%
US00773J2024
6.56%
LIVANOVA
6.39%
MIRUM PHARMACEUTICALS INC
4.69%
UTD THERAPEUT
4.43%
US6402683063
4.39%
KALVISTA PHARMACEUTICALS INC
4.33%
GUARDANT HEALTH INC
3.94%
BRIDGEBIO PHARMA
3.81%
TRANSMEDICS GROUP
3.78%
SAVARA INC
3.34%
TREVI THERAPEUTICS
3.29%
US9229671048
2.75%
AXSOME THERA CMN STK
2.37%
XPH
ORGANON & CO
3.72%
CORCEPT THERAPEUTICS
2.48%
US29337E1029
2.41%
AXSOME THERA CMN STK
2.34%
OMEROS
2.20%
PERRIGO CO PLC
2.17%
US6402683063
2.08%
TREVI THERAPEUTICS
2.07%
TERNS PHARMACEUTICALS
2.03%
US45579U1097
2.01%
PACIRA BIOSCIENCES INC
2.00%
HARROW HEALTH
1.97%
JAZZ PHARMACEUTICALS
1.97%
HARMONY BIOSCIENCES HLDG
1.95%
ROYALTY PHARMA
1.93%
Frequently asked questions about LFSC and XPH
How have the LFSC and XPH ETFs performed in 2026?
As of June 11, 2026, LFSC is up 8.38% year-to-date (YTD), while XPH has returned 6.83%. That puts LFSC better performer ahead so far this year.
Which ETF is attracting more investor money: LFSC or XPH?
Year-to-date, the LFSC ETF saw +$5M in flows, compared to +$110M for XPH.
Which ETF is more volatile: LFSC or XPH?
Over the past year, LFSC had a volatility of 26.55%, while XPH experienced 21.47%.
Which ETF is bigger: LFSC or XPH?
As of June 11, 2026, LFSC holds $106.22 M in assets under management (AUM), while XPH manages $362.12 M.
What sectors do the LFSC and XPH ETFs invest in?
LFSC leans toward sectors like Health Care. Meanwhile, XPH focuses on Health Care.
What are the top holdings of the LFSC ETF and XPH ETF?
LFSC top holdings include COGENT BIOSCIENCES, TRAVERE THERAPEUTICS INC and US00773J2024. XPH holds in its top three: ORGANON & CO, CORCEPT THERAPEUTICS and US29337E1029.
Which ETF is more diversified: LFSC or XPH?
LFSC holds 46 securities with 69.25% of its assets in the top 15. XPH has 58 securities and a top 15 weight of 33.31%.
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