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IHEvsXLVIETF Comparison
The Health Care Select Sector SPDR Premium Income Fund
iShares U.S. Pharmaceuticals ETF (IHE) belongs to the US Health Care segment. The Health Care Select Sector SPDR Premium Income Fund (XLVI) is part of the Options Strategies segment. Both ETFs have the same top 3 sector exposures: and Health Care. IHE is more expensive with a Total Expense Ratio (TER) of 0.38%, versus 0.35% for XLVI. IHE is up 4.3% year-to-date (YTD) with +$129M in YTD flows. XLVI performs worse with 0.28% YTD performance, and +$2M in YTD flows. Run a side-by-side ETF comparison of IHE and XLVI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
IHE vs XLVI performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IHE XLVI | -1.82%-1.07% | +5.93%+1.89% | +4.30%+0.28% | +28.47%n/a | +63.32%n/a | +61.21%n/a |
| Flows | IHE XLVI | +$9M+$788K | +$154M+$3M | +$129M+$2M | +$248M- | +$359M- | +$393M- |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IHE XLVI | +15.86%+10.15% | +20.40%n/a | +15.94%n/a | +15.80%n/a |
| Max drawdown | IHE XLVI | -4.49%-3.26% | -14.18%n/a | -16.04%n/a | -16.12%n/a |
| Max drawdown duration | IHE XLVI | 10d10d | 150dn/a | 210dn/a | 669dn/a |
IHE | XLVI | |
Last sale 3/12/2026 at 1:30 PM | $86.66 | $25.54 |
| Previous close 03/11/2026 | $88.40 | $25.92 |
| Consolidated volume 03/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Create an account to view replication metrics
IHE | XLVI | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
IHE | XLVI | |
|---|---|---|
| Last price | $86.66 | $25.54 |
| 1D performance | -1.97% | -1.47% |
| AuM | $1.02 B | $13.24 M |
| E/R | 0.38% | 0.35% |
Countries
Sectors
Diversification
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
Top 15 holdings
How have the IHE and XLVI ETFs performed in 2026?
As of March 11, 2026, IHE is up 4.3% year-to-date (YTD), while XLVI has returned 0.28%. That puts IHE better performer ahead so far this year.
Which ETF is attracting more investor money: IHE or XLVI?
Year-to-date, the IHE ETF saw +$129M in flows, compared to +$2M for XLVI.
Which ETF is bigger: IHE or XLVI?
As of March 11, 2026, IHE holds $1.02 B in assets under management (AUM), while XLVI manages $13.24 M.
What sectors do the IHE and XLVI ETFs invest in?
IHE leans toward sectors like Health Care. Meanwhile, XLVI focuses on Health Care.
What are the top holdings of the IHE ETF and XLVI ETF?
IHE top holdings include JOHNSON&JOHNSON, LILLY and MERCK & CO INC. XLVI holds in its top three: LILLY, JOHNSON&JOHNSON and ABBVIE.
Which ETF is more diversified: IHE or XLVI?
IHE holds 56 securities with 84.8% of its assets in the top 15. XLVI has 60 securities and a top 15 weight of 69.69%.
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